Relationship between Th1/ Th2 cytokines and severity of acute lung injury secondary to sepsis [PDF]
"Objective To analyze the effects of helper T cells（Th）1 and Th2 cytokines on the severity of acute lung injury（ALI）secondary to sepsis and to analyze their roles in evaluating the occurrence of ALI secondary to sepsis.Methods Clinical data of 206 ...
FU Daoliang，CHEN Dejian，REN Lei，HOU Xiaolin
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An experimental study about the value of presepsin for the diagnosis of burn sepsis in early phase, prognosis and instruction of antibiotic therapy [PDF]
, 2016 研究目的 脓毒症是大面积烧(烫)伤、严重创伤、休克及各种重度感染等临床急危重症患者的严重并发症，是全身炎症反应综合征的基础上合并感染或高度可疑感染灶。脓毒症是大面积烧伤患者主要死因之一，烧伤脓毒症患者病情进展迅速，病死率极高，治疗费用惊人。因此早期预测脓毒症的发生发展，早期诊断并干预，是降低脓毒症发病率及病死率的关键。脓毒症的发生与发展伴随着大量病理生理的变化，其中就包括各种炎症生物标记物的变化。目前临床上有很多关于脓毒症早期监测以及预后的指标的研究，如广泛应用的血清学预警指标血清降钙素原（PCT）、C-
余东启
core
Research progress on the pathogenesis of acute lung injury in sepsis [PDF]
Sepsis is a systemic inflammatory response syndrome caused by severe infection leading to host dysfunction，often involving multiple organs and causing functional failure.
WANG Qin，YU Xu，LI Qingying，LU Yibin
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眼镜蛇毒因子抑制补体激活对脓毒症大鼠血清细胞因子的影响 [PDF]
, 2018 目的:观察眼镜蛇毒因子(cobra venom factor,CVF)对脓毒症大鼠外周血中肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)和白介素-10(IL-10)的影响。方法:选取清洁级雄性SD大鼠144只,按照随机数字表法将大鼠分为A组(假手术组)、B组(脓毒症组)、C组(CVF预处理组),各48只;各组按照标本采集点的不同又分为术后2、4、8、12、16、24 h六个时间点亚组,各8只。B、C组采用盲肠结扎穿孔术(CLP)制作脓毒症大鼠模型;C组大鼠在CLP术前静脉注射CVF,而A ...
康福新 +5 more
core
Predictive value of serum cartilage glycoprotein⁃39 and mitochondrial uncoupling protein 2 for prognosis of drug⁃resistant Klebsiella pneumoniae sepsis [PDF]
"Objective To analyze the association of serum levels of cartilage glycoprotein⁃39（YKL⁃40），and mitochondrial uncoupling protein 2（UCP2）with the occurrence and prognosis of drug⁃resistant Klebsiella pneumoniae（KP）sepsis. Methods Prospectively，100 patients
ZHOU Pengpeng，XIA Honglin，LIU Yuling，LI Mei，HAO Weimin
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Predictive value of bone morphogenetic protein 9 and monocyte human leukocyte antigen⁃DR in prognosis of patients with sepsis [PDF]
"Objective To investigate the associations of serum level of bone morphogenetic protein 9（BMP9）and monocyte human leukocyte antigen⁃DR（mHLA⁃DR）expression rate in peripheral blood with the prognosis of sepsis，and to evaluate their predictive value for ...
WANG Shuo*，YANG Wenxue，WANG Wei，YIN Jie，WANG Xiujuan，ZHOU Xinjian，CHEN Yuehong，WANG Ling
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Research progress on the regulation of signal pathways related to lung injury in sepsis by the active components of traditional Chinese medicine [PDF]
Sepsis is a systemic inflammatory response syndrome caused by infection，with resulting organ dysfunction being the key factor in mortality. The lung is one of the organs most frequently affected by sepsis. Recent studies have shown that active components
RONG Jilintai*，SU He，ZHANG Ruifen，ZHANG Hairong，JIA Tingting，GUO Sihan，ZHAO Jian，LI Xiao，ZHONG Xin
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Zhongguo shiyan zhenduanxue, 2013 脓毒症（sepsis）是指由细菌或其他病原体感染引起的全身炎症反应综合征。据报道,可引起脓毒症的病原体包括细菌、病毒、真菌、寄生虫等。在临床上,脓毒症是由于机体过度炎症反应或者炎症失控的结果,而非由于感染的病原体或毒素直接作用所致,但在很多情况下,在病原体得到清除后,脓毒症仍可能继续发展,甚至导致脓毒性休克。目前对于脓毒症的诊断仍缺乏金标准 ...
金晔, 王炜
doaj
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的了解脓毒症患儿腹腔内高压（IAH）的发生率，并探讨腹腔内压力变化与脓毒症预后的关系。方法将2014年1月至2016年1月期间入住我院儿童重症监护室脓毒症患儿纳入前瞻性队列观察性研究，入组年龄>28 d至≤18岁、PICU治疗时间>24 h；排除对象：年龄≤28 d、使用神经肌肉阻滞、神经源性膀胱或膀胱手术史患儿。采用膀胱测压法监测腹腔内压力（IAP）并记录相关临床资料。采用时间依赖受试者工作特征曲线（survival ROC）确定IAP对脓毒症60 d内死亡的预测价值 ...
梁玉坚, 李易娟, 李素萍, 唐雯
doaj
Progress in the treatment of sepsis⁃associated acute kidney injury [PDF]
"Sepsis⁃associated acute kidney injury（SA⁃AKI）is a common critical illness in hospitalized patients，characterized by high incidence，high mortality. The pathogenesis of SA ⁃ AKI is complex，with both direct mechanisms related to infection and indirect ...
LIANG Xinyue*，ZHOU Yun
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