Results 21 to 30 of about 1,839 (147)
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的了解脓毒症患儿腹腔内高压（IAH）的发生率，并探讨腹腔内压力变化与脓毒症预后的关系。方法将2014年1月至2016年1月期间入住我院儿童重症监护室脓毒症患儿纳入前瞻性队列观察性研究，入组年龄>28 d至≤18岁、PICU治疗时间>24 h；排除对象：年龄≤28 d、使用神经肌肉阻滞、神经源性膀胱或膀胱手术史患儿。采用膀胱测压法监测腹腔内压力（IAP）并记录相关临床资料。采用时间依赖受试者工作特征曲线（survival ROC）确定IAP对脓毒症60 d内死亡的预测价值 ...
梁玉坚, 李易娟, 李素萍, 唐雯
doaj
Clinical features and risk factors of sepsis-induced cardiomyopathy in children with sepsis [PDF]
Objective To investigate the clinical features and risk factors of sepsis-induced cardiomyopathy in children with sepsis， aiming to provide reference for enhancing the diagnosis and treatment levels of clinicians.
GUO Enyu, FANG Yanling, GENG Huaxiao, WANG Wenjie, LI Shanshan, MENG Xianglan, ZHANG Haifang
core +1 more source
, 2018 纳米酶是具有酶催化活性的纳米材料,对比天然酶,纳米酶具有价格便宜、制备工艺简单、稳定性好、循环利用率高等优势.早期的纳米酶研究主要集中在检测方面,包括检测离子、小分子、核酸、蛋白质、癌细胞等,随着对纳米酶的深入了解,研究人员发现纳米酶在疾病治疗领域也具有巨大的应用前景.本论文将介绍纳米酶在细菌感染、炎症、癌症 ...
任劲松 +4 more
core +1 more source
The Study of the Value of High Mobility Group Protein B1 Combined with Acute Physiological Score in the Diagnosis and Prognosis of Children with Severe Pneumonia [PDF]
, 2022 BackgroundSevere pneumonia in children is a common respiratory critical illness, and accurate assessment of its prognosis is the key to reasonable clinical decision-making. High mobility group protein B1 (HMGB1) and acute physiology score (APS) have high
KANG Ping, LI Yi, TANG Yu
core +1 more source
Linchuang shenzangbing zazhi, 2015 近年来,脓毒症的发病率及病死率逐年增加,已经成为威胁儿童生命的十大死亡原因之一。目前一般认为脓毒症是全身性炎症反应、内皮细胞损伤及凝血系统激活之间相互作用的结果,可进展为严重脓毒症、脓毒性休克和多器官功能障碍综合征。儿童因为机体各组织器官及免疫系统尚未发育成熟,因而脓毒症在此阶段易发[1]。肾脏是容易受到脓毒症打击的重要靶器官 ...
邵启国, 王建刚
doaj
Effects of different therapeutic doses of CRRT on serum PGE2 and I⁃FABP levels and prognosis in patients with severe sepsis [PDF]
"Objective To analyze the effects of continuous renal replacement therapy（CRRT） dose on serum prostaglandin⁃2（PGE2）and intestinal fatty acid⁃binding protein（I⁃FABP）levels and prognosis in patients with severe sepsis，and to reveal the dynamic pattern of ...
XIAO Hui，LI Shanglin，FENG Xincheng，TONG Xia
core +2 more sources
Progress in the role of exosomes in sepsis⁃induced cardiomyopathy [PDF]
"Sepsis is a life⁃ threatening organ dysfunction triggered by a dysregulated host response to infection. Sepsis⁃ induced cardiomyopathy（SICM）is an acute cardiac condition caused by sepsis，characterized by high incidence and extremely high mortality ...
ZHENG Ye*，LI Shaoling，HAN Fei
core +2 more sources
ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用
Zhongguo shiyan zhenduanxue, 2020 目的探讨ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用。方法选取2018年2月-2019年9月我院收治的脓毒症患者76例,根据其症状表现将其分为单纯脓毒症组43例,合并急性肺损伤组21例,以及同时合并急性肺损伤、呼吸窘迫综合征组12例,分析其ICAM-1水平对于疾病诊断以及预后评估的价值。结果同时合并肺损伤与呼吸窘迫综合征组患者ICAM-1水平以及SOFA评分均高于脓毒症组以及合并肺损伤组 ...
王晓林, 李静, 黄艳丽
doaj
尿NGAL、Scr、Cys C在脓毒血症并发急性肾损伤诊断中的价值研究
Zhongguo shiyan zhenduanxue, 2021 脓毒血症常合并多种并发症,其中急性肾损伤(AKI)是一种常见的合并症[1]。当合并AKI时,患者肾小球滤过能力显著降低,含氮以及非含氮代谢产物发生蓄积[2],提高了患者的死亡率。所以,探寻一种稳定且可靠的可评估脓毒血症合并AKI患者病情以及预后状况的医学指标,对疾病的治疗具有十分重要的临床价值[3]。近年来,尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、胱抑素(Cys C)、血清肌酐(Scr)等指标用于脓毒血症合并AKI的临床诊断[4]。本研究以98例脓毒血症患者作为研究对象,探讨了尿NGAL、Scr、
佟庆, 侯燕燕, 田颖, 范志强
doaj
Associations between serum complement component 3a and sC5b⁃9 levels with the prognosis of sepsis patients [PDF]
"Objective To investigate the associations of serum complement component 3a（C3a）and soluble terminalcomplement complex C5b⁃9（sC5b⁃9）levels with the severity of sepsis and 28⁃day clinical prognosis among patients，and to provide new biomarker references ...
SU Yixing，BAO Lei，YU Jun'an，GU Zhijian
core +2 more sources