Relationship between Th1/ Th2 cytokines and severity of acute lung injury secondary to sepsis [PDF]
"Objective To analyze the effects of helper T cells（Th）1 and Th2 cytokines on the severity of acute lung injury（ALI）secondary to sepsis and to analyze their roles in evaluating the occurrence of ALI secondary to sepsis.Methods Clinical data of 206 ...
FU Daoliang，CHEN Dejian，REN Lei，HOU Xiaolin
core +2 more sources
An experimental study about the value of presepsin for the diagnosis of burn sepsis in early phase, prognosis and instruction of antibiotic therapy [PDF]
, 2016 研究目的 脓毒症是大面积烧(烫)伤、严重创伤、休克及各种重度感染等临床急危重症患者的严重并发症，是全身炎症反应综合征的基础上合并感染或高度可疑感染灶。脓毒症是大面积烧伤患者主要死因之一，烧伤脓毒症患者病情进展迅速，病死率极高，治疗费用惊人。因此早期预测脓毒症的发生发展，早期诊断并干预，是降低脓毒症发病率及病死率的关键。脓毒症的发生与发展伴随着大量病理生理的变化，其中就包括各种炎症生物标记物的变化。目前临床上有很多关于脓毒症早期监测以及预后的指标的研究，如广泛应用的血清学预警指标血清降钙素原（PCT）、C-
余东启
core
Diagnostic value of serum TLR9 and UCP2 for sepsis complicated with acute kidney injury [PDF]
"Objective To investigate the diagnostic value of serum Toll⁃like receptor 9（TLR9）and uncoupling protein 2（UCP2）for sepsis patients complicated with acute kidney injury（AKI），and to provide a reference for clinical diagnosis and treatment.
XU Guangyu，XU Wenbin，HUANG Fei
core +2 more sources
眼镜蛇毒因子抑制补体激活对脓毒症大鼠血清细胞因子的影响 [PDF]
, 2018 目的:观察眼镜蛇毒因子(cobra venom factor,CVF)对脓毒症大鼠外周血中肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)和白介素-10(IL-10)的影响。方法:选取清洁级雄性SD大鼠144只,按照随机数字表法将大鼠分为A组(假手术组)、B组(脓毒症组)、C组(CVF预处理组),各48只;各组按照标本采集点的不同又分为术后2、4、8、12、16、24 h六个时间点亚组,各8只。B、C组采用盲肠结扎穿孔术(CLP)制作脓毒症大鼠模型;C组大鼠在CLP术前静脉注射CVF,而A ...
康福新 +5 more
core
Progress in the treatment of sepsis⁃associated acute kidney injury [PDF]
"Sepsis⁃associated acute kidney injury（SA⁃AKI）is a common critical illness in hospitalized patients，characterized by high incidence，high mortality. The pathogenesis of SA ⁃ AKI is complex，with both direct mechanisms related to infection and indirect ...
LIANG Xinyue*，ZHOU Yun
core +2 more sources
Predictive value of bone morphogenetic protein 9 and monocyte human leukocyte antigen⁃DR in prognosis of patients with sepsis [PDF]
"Objective To investigate the associations of serum level of bone morphogenetic protein 9（BMP9）and monocyte human leukocyte antigen⁃DR（mHLA⁃DR）expression rate in peripheral blood with the prognosis of sepsis，and to evaluate their predictive value for ...
WANG Shuo*，YANG Wenxue，WANG Wei，YIN Jie，WANG Xiujuan，ZHOU Xinjian，CHEN Yuehong，WANG Ling
core +2 more sources
Research progress on the regulation of signal pathways related to lung injury in sepsis by the active components of traditional Chinese medicine [PDF]
Sepsis is a systemic inflammatory response syndrome caused by infection，with resulting organ dysfunction being the key factor in mortality. The lung is one of the organs most frequently affected by sepsis. Recent studies have shown that active components
RONG Jilintai*，SU He，ZHANG Ruifen，ZHANG Hairong，JIA Tingting，GUO Sihan，ZHAO Jian，LI Xiao，ZHONG Xin
core +2 more sources
Zhongguo shiyan zhenduanxue, 2019 脓毒症(Sepsis)是宿主对病原体的异常的反应而引起危及生命的器官功能障碍[1]。由于脓毒症的发病机制复杂,虽然人类对脓毒症的认识在不断进步,以抗生素为基础的治疗技术在不断的提高,但全球每年约有1900万新发的脓毒症患者[2],脓毒症的病死率仍高达25%到80%[3]。免疫抑制是脓毒症发病机制中研究最多的机制。T淋巴细胞(T lymphocytes)在脓毒症发病机制中起关键要作用[4]。本文综述T淋巴细胞在脓毒症的发病机制中的作用。
薛秋丽, 董丽华, 刘忠民
doaj
Early alarming effect of serum heparin-binding protein on prognosis and occurrence of sepsis in severely burned patients [PDF]
Objective·To study early expression levels of serum heparin-binding protein (HBP) and its potential value in early alarming for prognosis and occurrence of sepsis in patients with severe burns.Methods·Retrospective analysis was performed on medical ...
SONG Chenlu, XIANG Jun, YANG Huizhong
core +1 more source
Zhongguo shiyan zhenduanxue, 2013 脓毒症（sepsis）是指由细菌或其他病原体感染引起的全身炎症反应综合征。据报道,可引起脓毒症的病原体包括细菌、病毒、真菌、寄生虫等。在临床上,脓毒症是由于机体过度炎症反应或者炎症失控的结果,而非由于感染的病原体或毒素直接作用所致,但在很多情况下,在病原体得到清除后,脓毒症仍可能继续发展,甚至导致脓毒性休克。目前对于脓毒症的诊断仍缺乏金标准 ...
金晔, 王炜
doaj