Results 21 to 30 of about 1,581 (147)
Zhongguo shiyan zhenduanxue, 2019 脓毒症(Sepsis)是宿主对病原体的异常的反应而引起危及生命的器官功能障碍[1]。由于脓毒症的发病机制复杂,虽然人类对脓毒症的认识在不断进步,以抗生素为基础的治疗技术在不断的提高,但全球每年约有1900万新发的脓毒症患者[2],脓毒症的病死率仍高达25%到80%[3]。免疫抑制是脓毒症发病机制中研究最多的机制。T淋巴细胞(T lymphocytes)在脓毒症发病机制中起关键要作用[4]。本文综述T淋巴细胞在脓毒症的发病机制中的作用。
薛秋丽, 董丽华, 刘忠民
doaj
Clinical features and risk factors of sepsis-induced cardiomyopathy in children with sepsis [PDF]
Objective To investigate the clinical features and risk factors of sepsis-induced cardiomyopathy in children with sepsis， aiming to provide reference for enhancing the diagnosis and treatment levels of clinicians.
GUO Enyu, FANG Yanling, GENG Huaxiao, WANG Wenjie, LI Shanshan, MENG Xianglan, ZHANG Haifang
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The Study of the Value of High Mobility Group Protein B1 Combined with Acute Physiological Score in the Diagnosis and Prognosis of Children with Severe Pneumonia [PDF]
, 2022 BackgroundSevere pneumonia in children is a common respiratory critical illness, and accurate assessment of its prognosis is the key to reasonable clinical decision-making. High mobility group protein B1 (HMGB1) and acute physiology score (APS) have high
KANG Ping, LI Yi, TANG Yu
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Linchuang shenzangbing zazhi, 2015 近年来,脓毒症的发病率及病死率逐年增加,已经成为威胁儿童生命的十大死亡原因之一。目前一般认为脓毒症是全身性炎症反应、内皮细胞损伤及凝血系统激活之间相互作用的结果,可进展为严重脓毒症、脓毒性休克和多器官功能障碍综合征。儿童因为机体各组织器官及免疫系统尚未发育成熟,因而脓毒症在此阶段易发[1]。肾脏是容易受到脓毒症打击的重要靶器官 ...
邵启国, 王建刚
doaj
Progress in the role of exosomes in sepsis⁃induced cardiomyopathy [PDF]
"Sepsis is a life⁃ threatening organ dysfunction triggered by a dysregulated host response to infection. Sepsis⁃ induced cardiomyopathy（SICM）is an acute cardiac condition caused by sepsis，characterized by high incidence and extremely high mortality ...
ZHENG Ye*，LI Shaoling，HAN Fei
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ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用
Zhongguo shiyan zhenduanxue, 2020 目的探讨ICAM-1对脓毒症所致急性肺损伤与呼吸窘迫综合征的临床诊断和预后评估作用。方法选取2018年2月-2019年9月我院收治的脓毒症患者76例,根据其症状表现将其分为单纯脓毒症组43例,合并急性肺损伤组21例,以及同时合并急性肺损伤、呼吸窘迫综合征组12例,分析其ICAM-1水平对于疾病诊断以及预后评估的价值。结果同时合并肺损伤与呼吸窘迫综合征组患者ICAM-1水平以及SOFA评分均高于脓毒症组以及合并肺损伤组 ...
王晓林, 李静, 黄艳丽
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尿NGAL、Scr、Cys C在脓毒血症并发急性肾损伤诊断中的价值研究
Zhongguo shiyan zhenduanxue, 2021 脓毒血症常合并多种并发症,其中急性肾损伤(AKI)是一种常见的合并症[1]。当合并AKI时,患者肾小球滤过能力显著降低,含氮以及非含氮代谢产物发生蓄积[2],提高了患者的死亡率。所以,探寻一种稳定且可靠的可评估脓毒血症合并AKI患者病情以及预后状况的医学指标,对疾病的治疗具有十分重要的临床价值[3]。近年来,尿中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、胱抑素(Cys C)、血清肌酐(Scr)等指标用于脓毒血症合并AKI的临床诊断[4]。本研究以98例脓毒血症患者作为研究对象,探讨了尿NGAL、Scr、
佟庆, 侯燕燕, 田颖, 范志强
doaj
Early alarming effect of serum heparin-binding protein on prognosis and occurrence of sepsis in severely burned patients [PDF]
Objective·To study early expression levels of serum heparin-binding protein (HBP) and its potential value in early alarming for prognosis and occurrence of sepsis in patients with severe burns.Methods·Retrospective analysis was performed on medical ...
SONG Chenlu, XIANG Jun, YANG Huizhong
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, 2018 纳米酶是具有酶催化活性的纳米材料,对比天然酶,纳米酶具有价格便宜、制备工艺简单、稳定性好、循环利用率高等优势.早期的纳米酶研究主要集中在检测方面,包括检测离子、小分子、核酸、蛋白质、癌细胞等,随着对纳米酶的深入了解,研究人员发现纳米酶在疾病治疗领域也具有巨大的应用前景.本论文将介绍纳米酶在细菌感染、炎症、癌症 ...
任劲松 +4 more
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Advances in Helicobacter pylori infection involved in gastric cancer metastasis [PDF]
, 2023 Gastric cancer is a common cancer of the gastrointestinal tract, highly occurring in East and Southeast Asian. Roughly more than 50% of the population is exposed to Helicobacter pylori (H. pylori) infection worldwide. H.
CHEN Siyu +4 more
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