Results 1 to 10 of about 6,050 (147)
Autoimmune polyendocrine syndrome type 2 complicated with hyperthyroidism crisis and diabetic acute complications： a case report and literature review [PDF]
, 2023 Objective To enhance clinicians’ diagnosis and treatment capability for autoimmune polyendocrine syndrome type 2 （APS-2），and reduce missed diagnosis and misdiagnosis.
Jian Li, Wu Qinan, Zhao Qiquan, LYU Xinlu
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Diagnostic thinking of renal capillary endothelial cell hyperplasia [PDF]
, 2023 The diseases pathologically manifested with endothelial cell hyperplasia can present with multiple clinical manifestations， which correspond to different types of clinical diseases.
Lü Guangna, Yan Yu
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Zhongguo shiyan zhenduanxue, 2022 1型糖尿病（T1DM）是一种以高血糖为主要直接表现的自身免疫性疾病。我国发病率增加明显，疾病负担重，患者身心健康及生活质量均受到严重影响，治疗现状急需改进，故倍受关注[1]。且因内分泌系统疾病与疾病自身免疫过程的密切相互作用，使得T1DM患者更易合并其他自身免疫性疾病，进而有更大可能被诊断为自身免疫性多内分泌腺病综合征（APS）。
董佳婧, 刘殿媛, 王清
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Zhongguo shiyan zhenduanxue, 2021 桥本甲状腺炎(HT)是最常见的自身免疫性甲状腺疾病(AITD),主要表现为甲状腺功能减退,病因与自身免疫功能紊乱相关,部分患者可合并其他自身免疫性疾病,如自身免疫性肾病、系统性红斑狼疮、干燥综合征、类风湿关节炎等。当AITD伴有蛋白尿时称为AITD肾病,其病理类型多为膜性肾病,伴IgA肾病(IgAN)报道不多,本文报道1例桥本甲状腺炎伴IgA肾病的病例,以期为临床实践提供参考。
陈奕颖, 付少杰, 黄文洁, 陈志
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Ethical Reflection on Standardized Management of Intestinal Microbiota Transplantation [PDF]
, 2017 肠道微生态系统是人体健康所必需的重要且复杂的生物系统。肠道微生态系统的紊乱参与人体多种疾病的发生发展过程。而肠菌移植技术可有效调节肠道菌群，修复失衡的肠道微生态，为当今多种胃肠道及胃肠以外疾病的治疗带来新的突破。然而，目前尚缺乏完整的、系统性的肠菌移植技术管理规范。就肠菌移植技术规范化管理所涉及的内容进行探讨，并从医学伦理学角度思考规范化管理中所涉及的伦理问题，以期推动肠菌移植技术的临床应用。Intestinal microecology is an important and complex ...
任建林 +4 more
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Development of interleukin-21 as a therapeutic drug [PDF]
, 2017 白细胞介素21; (IL-21)是一种具有多效免疫调节活性的细胞因子,参与先天性免疫反应和适应性免疫反应的多个环节,与自身免疫性疾病、肿瘤、病毒感染等疾病的发病过; 程相关。研究表明,在动物模型中通过增强或抑制IL-21的生物学功能对多种疾病具有治疗意义,多项以重组人IL-21为受试药物的临床试验已经开展。本; 文就IL-21的生物学功能,以及IL-21作为生化药物在临床治疗中的研究进展和应用前景进行阐述。Interleukin-21 (IL-21) is a cytokine with broad ...
刘狄彤 +5 more
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Establishment and evaluation of nomogram for differential diagnosis of systemic lupus erythematosus based on laboratory indications [PDF]
Objective·To establish a nomogram for the differential diagnosis of early systemic lupus erythematosus (SLE) and other autoimmune diseases based on laboratory indications, and to evaluate its efficacy.Methods·A total of 535 SLE patients admitted to the ...
CHEN Liubao +4 more
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, 2017 抗中性粒细胞胞质抗体（antineutrophil cytoplasmic autoantibody,ANCA）相关性小血管炎（ANCA associated small vessel vasculiltis,AASV）是以中性粒细胞、单核细胞胞质成分为靶抗原的一组自身免疫性系统性疾病,主要包括肉芽肿性多血管炎、显微镜下多血管炎和嗜酸性肉芽肿性多血管炎。福建省自然科学基金（No ...
彭卫华, 陈凌舟
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Factors Associated with Thrombosis in Primary Immune Thrombocytopenia [PDF]
, 2022 BackgroundPatients with primary immune thrombocytopenia (ITP) , a hemorrhagic disease characterized by thrombocytopenia, have increased incidence of thrombotic events, which increases the treatment difficulty.
YANG Shuo, WANG Yong, CHEN Shuxia, ZHAO Mingfeng
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Treatment of refractory severe dry eye with 0.1% tacrolimus eyedrops [PDF]
, 2016 目的：评估0.1%他克莫司滴眼液治疗难治性重度干眼疗效。 方法：本研究招募已使用人工泪液合并激素治疗半年或半年以上，但干眼症状及体征未见明显缓解的重度干眼患者26名。所有给予0.1%他克莫司滴眼液合并人工泪液治疗，并于治疗前、治疗后1月、2月及3月观察干眼相关临床指标，包括：干眼症状评分(OcularSurfaceDiseaseIndex，OSDI)、泪膜破裂时间(Tearbreakuptime，TBUT)、泪液分泌试验(SchirmerI)、角膜荧光素钠染色评分 ...
杨舒
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