Results 1 to 10 of about 6,048 (140)

急性白血病体外药物敏感性测定——一种简便、迅速、切实可行的方法 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 1985
用96孔培养板培养病人骨髓白血病细胞作药物抑制氚标记脱氧胸苷(~3H-TdR)参入试验。对14例白血病患者作26次试验,结果表明13例急性白血病24次试验药物在体外对~3H-TdR参入的抑制率与临床用药疗效相当一致,阿糖胞苷和三尖杉酯碱对~3H-TdR参入细胞的抑制试验可以有效地预测疗效,本法与其他试验方法比较,具有迅速简便,切实可行等优点。慢粒急变1例作2次试验,结果与临床疗效不一致。急性白血病的治疗一向以化疗为主,不同病人或不同病期对化疗药物的敏感性均不同 ...
苏勇庄
doaj   +2 more sources

Distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock [PDF]

open access: yes, 2022
Objective To explore the distribution of blood culture pathogens and clinical characteristics in children with acute leukemia complicated with septic shock.
Liu Tinghua, Lei Jiaying, Mai Yougang
core   +1 more source

Combined use of venetoclax and azacitidine in treatment of acute myeloid leukemia complicated with disseminated Fusarium infection: a case report [PDF]

open access: yes, 2022
Acute myeloid leukemia (AML) is a malignant clonal disease originating from hematopoietic stem/progenitor cells. Chemotherapy is the main treatment. If not effectively treated after 2 courses of standard treatment, these patients can be diagnosed with ...
Guo Jun, Wei Pei, Tong Yajun, Chen Ting
core   +1 more source

Comparison between clinical evaluations and laboratory findings and the impact of biofilm on antimicrobial susceptibility in vitro in canine otitis externa

open access: yesVeterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023
Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani   +6 more
wiley   +1 more source

Non-clostridial Gas-forming Infection in Diabetes:Clinical Analysis of Two Cases [PDF]

open access: yes, 2022
Non-clostridial organism can produce pneumoderma by breaking down sugar and other substrates in necrotic tissues, and non-clostridial gas-forming infection is usually seen in diabetic patients with poor glycemic control.
WU Yuan, LYU Hongjun, YAO Xiaoli, LIU Juan
core   +1 more source

The influence of posttraumatic stress disorder treatment on anxiety sensitivity: Impact of prolonged exposure, sertraline, and their combination

open access: yesJournal of Traumatic Stress, Volume 36, Issue 1, Page 157-166, February 2023., 2023
Abstract Trauma‐informed beliefs often decrease during posttraumatic stress disorder (PTSD) treatment. This may also extend to anxiety sensitivity (AS), defined as a fear of anxiety‐related sensations and beliefs that anxiety is dangerous and/or intolerable.
Matthew T. Luciano   +11 more
wiley   +1 more source

Clindamycin resistance of skin derived Staphylococcus pseudintermedius is higher in dogs with a history of antimicrobial therapy

open access: yesVeterinary Dermatology, Volume 31, Issue 4, Page 305-e75, August 2020., 2020
Background – In the Netherlands there is a lack of data regarding resistance of Staphylococcus pseudintermedius to the systemic antimicrobial drugs used for the treatment of superficial pyoderma. Objectives – To assess antimicrobial resistance, with emphasis on resistance to clindamycin and meticillin, in clinical isolates of S.
Catharina M.M. van Damme   +3 more
wiley   +1 more source

Analysis of contamination and pathogenic characteristics of Salmonella in the processing of pre-packed cooked meat products [PDF]

open access: yes, 2023
ObjectiveTo analyze the molecular characteristics and antibiotic susceptibility of Salmonella isolates and investigate the contamination of Salmonella in pre-packed cooked meat products during food processing.MethodsAccording to the sampling requirements
LIU Weichao   +3 more
core   +1 more source

In vitro killing of canine strains of Staphylococcus pseudintermedius and Escherichia coli by cefazolin, cefovecin, doxycycline and pradofloxacin over a range of bacterial densities

open access: yesVeterinary Dermatology, Volume 31, Issue 3, Page 187-e39, June 2020., 2020
Background Bacterial densities likely fluctuate during infection and may exceed the bacterial density used in susceptibility testing. As such, investigation of bacterial killing by antibiotics over a range of varying bacterial densities may provide important differences between compounds and could impact drug selection for therapy.
Joseph M. Blondeau, Shantelle D. Fitch
wiley   +1 more source

Changes in drug resistance of Acinetobacter baumannii during the change of meropenem concentration in the environment and its mechanism [PDF]

open access: yes, 2023
Objective·To explore the mechanism of changes in resistance to meropenem (MEM), a carbapenem drug, in Acinetobacter baumannii (A. baumannii) cultured in different antibiotic concentrations.Methods·Through changing the MEM concentration and ...
PENG Li   +4 more
core   +1 more source

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