Results 51 to 60 of about 136,961 (207)

Machine Learning‐Based Predictive Modeling Maximizes the Efficacy of mTOR/p53 Co‐Targeting Therapy Against AML

open access: yesCancer Science, Volume 116, Issue 11, Page 3040-3051, November 2025.
Although mTOR inhibitors show limited clinical efficacy against AML, this study demonstrates that combining mTOR inhibition with TP53 activation enhances anti‐leukemic effects. We also developed a gene scoring system (Rapa‐11) predicting rapamycin sensitivity and showed that monocytic AMLs with wild‐type TP53 and low Rapa‐11 scores are highly ...
Jingmei Li   +11 more
wiley   +1 more source

Effect of Huolong cupping therapy in the treatment of peripheral neuropathy in patients with multiple myeloma (火龙罐疗法对多发性骨髓瘤周围神经病变的干预效果)

open access: yes中西医结合护理
Objective To investigate the effect of Huolong cupping therapy in the treatment of peripheral neuropathy in patients with multiple myeloma. Methods A total of 60 multiple myeloma patients with peripheral neuropathy were randomly divided into the ...
ZHOU Xia (周霞), CHEN Huan (陈欢)
doaj   +1 more source

インドシアニングリーンを用いた,皮下乳腺全摘出術後の乳頭乳輪の血液灌流の測定 [PDF]

open access: yes, 2005
 The aim of this study is to investigate the blood supply of the normal nipple-areola complex (NAC) and the spared nipple-areola complex after a nipple-sparing mastectomy by the analysis of the fluorescence resulting from the indocyanine green dye (ICG ...
Yves Petit Jean   +2 more
core  

The Role of Histone Methyltransferase SETDB1 in Normal and Malignant Hematopoiesis

open access: yesCancer Science, Volume 116, Issue 9, Page 2331-2339, September 2025.
In this review, we discuss the role of SETDB1 in gene regulation, including an overview of its structural features and key cofactors. We also highlight the lineage‐specific roles of SETDB1 in both normal hematopoietic processes and hematological malignancies, emphasizing its function as an immune checkpoint molecule that suppresses natural killer cell ...
Yu‐Hsuan Chang, Susumu Goyama
wiley   +1 more source

Construction and application of a non-vomiting management mode in laminar flow ward for hematopoietic stem cell transplantation patients (造血干细胞移植患者层流舱内无呕管理模式的构建及应用)

open access: yes中西医结合护理
Objective To establish a non-vomiting management model of laminar flow ward for patients undergoing hematopoietic stem cell transplantation and analyze its clinical application effect, so as to reduce the incidence of nausea and vomiting and improve the
SU JiLiang (苏继亮)   +2 more
doaj   +1 more source

Research progress on traditional Chinese medicine animal models of post‐stroke depression and pathological insights

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 8, Page 1387-1399, August 2025.
Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang   +4 more
wiley   +1 more source

A novel approach for feline sporotrichosis pathogen detection based on loop‐mediated isothermal amplification

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 474-484, August 2025.
Background – Sporotrichosis is a chronic, mycotic infection caused by fungi of the genus Sporothrix. Zoonotic sporotrichosis occurs mainly through S. brasiliensis transmission, resulting from the organism's traumatic introduction via scratches or bites, or contact with exudate from contaminated cats.
Steffanie Amadei   +6 more
wiley   +1 more source

人文关怀在血液科优质护理服务中的应用

open access: yes实用医学研究, 2019
为了研究人文关怀在血液科优质护理服务中的应用,论文选用了2018 年5 月—2019 年5 月这一时间段内血液科的患者120 例,将其分为对照组和研究组,研究组采用人文关怀下的优质护理服务,而对照组采用普通护理形式。结果显示,患者出院时,明显研究组的满意度要高于对照组,该统计研究具有统计学意义(P0.05)。由此得出,将人文关怀应用到血液科优质护理服务中可以在很大程度上提升患者的满足度,进而提升临床护理工作的质量。
朋 苗, 瑞霞 张
semanticscholar   +1 more source

Automated multivolume placental reconstruction using three‐dimensional power Doppler ultrasound and infrared camera tracking

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 5, Page 624-632, May 2025.
ABSTRACT Objectives Placental insufficiency contributes to many obstetric pathologies, but there is no bedside clinical tool to evaluate placental perfusion. We have developed a method to acquire multiple three‐dimensional (3D) power Doppler (PD) ultrasound (US) volumes of placental vasculature, with infrared camera tracking of the precise spatial ...
A. Xue   +5 more
wiley   +1 more source

Clinical study on relieving bone pain in multiple myeloma using wrist-ankle acupuncture combined with Traditional Chinese Medicine nursing techniques based on the theory of combination of therapeutic methods (基于“杂合以治”理论腕踝针结合中医护理技术缓解多发性骨髓瘤骨病疼痛的临床研究)

open access: yes中西医结合护理
Objective Based on the theory of combination of therapeutic methods, this paper aims to investigate the clinical efficacy of combining wrist-ankle acupuncture with moxibustion and Chinese herbal paste application in relieving bone pain in patients with ...
LI Chunmei (李春梅)   +2 more
doaj   +1 more source

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