Results 31 to 40 of about 32,958 (186)

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang   +6 more
wiley   +1 more source

Whole Genome and Single‐Cell RNA Sequencing Reveals Clonal Evolution and Heterogeneity of Secondary Plasma Cell Leukemia: A Case Report

open access: yeseJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Secondary plasma cell leukemia (sPCL) is a rare, aggressive manifestation of multiple myeloma (MM). We report a 75‐year‐old Japanese man with anemia as the chief complaint and IgG‐λ MM that rapidly progressed to sPCL. Whole genome sequencing using Canopy revealed a major clone with a monoallelic TP53 mutation.
Tomotaka Suzuki   +4 more
wiley   +1 more source

Influence of Traditional Chinese Medicine emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease (中医情志护理干预对终末期肾病透析患者心理及生活质量的影响研究)

open access: yes中西医结合护理
Objective To investigate the influence of Traditional Chinese Medicine (TCM) emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease.
JIA Hengxia (贾恒霞)   +2 more
doaj   +1 more source

Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin   +4 more
wiley   +1 more source

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie   +2 more
wiley   +1 more source

Effect of Huolong cupping therapy in the treatment of peripheral neuropathy in patients with multiple myeloma (火龙罐疗法对多发性骨髓瘤周围神经病变的干预效果)

open access: yes中西医结合护理
Objective To investigate the effect of Huolong cupping therapy in the treatment of peripheral neuropathy in patients with multiple myeloma. Methods A total of 60 multiple myeloma patients with peripheral neuropathy were randomly divided into the ...
ZHOU Xia (周霞), CHEN Huan (陈欢)
doaj   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

Construction and application of a non-vomiting management mode in laminar flow ward for hematopoietic stem cell transplantation patients (造血干细胞移植患者层流舱内无呕管理模式的构建及应用)

open access: yes中西医结合护理
Objective To establish a non-vomiting management model of laminar flow ward for patients undergoing hematopoietic stem cell transplantation and analyze its clinical application effect, so as to reduce the incidence of nausea and vomiting and improve the
SU JiLiang (苏继亮)   +2 more
doaj   +1 more source

Machine Learning‐Based Predictive Modeling Maximizes the Efficacy of mTOR/p53 Co‐Targeting Therapy Against AML

open access: yesCancer Science, Volume 116, Issue 11, Page 3040-3051, November 2025.
Although mTOR inhibitors show limited clinical efficacy against AML, this study demonstrates that combining mTOR inhibition with TP53 activation enhances anti‐leukemic effects. We also developed a gene scoring system (Rapa‐11) predicting rapamycin sensitivity and showed that monocytic AMLs with wild‐type TP53 and low Rapa‐11 scores are highly ...
Jingmei Li   +11 more
wiley   +1 more source

The Role of Histone Methyltransferase SETDB1 in Normal and Malignant Hematopoiesis

open access: yesCancer Science, Volume 116, Issue 9, Page 2331-2339, September 2025.
In this review, we discuss the role of SETDB1 in gene regulation, including an overview of its structural features and key cofactors. We also highlight the lineage‐specific roles of SETDB1 in both normal hematopoietic processes and hematological malignancies, emphasizing its function as an immune checkpoint molecule that suppresses natural killer cell ...
Yu‐Hsuan Chang, Susumu Goyama
wiley   +1 more source

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