Results 41 to 50 of about 136,961 (207)

Fundamental study on intra-arterial chemotherapy with direct hemoperfusion [PDF]

open access: yes, 1985
膀胱癌に対する血液吸着を併用した制癌剤大量動注化学療法における制癌剤(CDDP, MMGおよびADM)の体内動態を, イヌ実験モデルを用い比較検討した.1)各制癌剤の血中濃度の経時的推移はほぼ同じ傾向を示し, すなわち末梢静脈血濃度は3薬剤ともに血液吸着併用群が非併用群より低値であり, 全身性副作用の軽減が示唆された.2)各薬剤に対する吸着筒のクリアランスは, 第1吸着筒ではMMGおよびADMでほぼ一定値を保ち, 前者で約82 ml/minおよび後者で約76~79 ml/minであったが ...
中野, 康治
core  

Whole Genome and Single‐Cell RNA Sequencing Reveals Clonal Evolution and Heterogeneity of Secondary Plasma Cell Leukemia: A Case Report

open access: yeseJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Secondary plasma cell leukemia (sPCL) is a rare, aggressive manifestation of multiple myeloma (MM). We report a 75‐year‐old Japanese man with anemia as the chief complaint and IgG‐λ MM that rapidly progressed to sPCL. Whole genome sequencing using Canopy revealed a major clone with a monoallelic TP53 mutation.
Tomotaka Suzuki   +4 more
wiley   +1 more source

Nursing management of drug extravasation during intravenous pumping of potassium chloride in a patient with multiple myeloma (1例多发性骨髓瘤患者静脉泵入氯化钾外渗的护理)

open access: yes中西医结合护理, 2021
This paper summarized the nursing management of drug extravasation during intravenous pumping of potassium chloride in a patient with multiple myeloma.
SONG Lihua (宋丽华), FENG Li (冯丽)
doaj   +1 more source

Relationship between abnormal symptoms of Prader-Willi syndrome model --Snord116 deletion mice and Ghrelin signaling pathway [PDF]

open access: yes, 2016
Prader–Willi综合症是以进食异常和血液Ghrelin异常升高为特征的遗传肥胖症。其病因是Snord116SnoRNA群的表达缺失。我们构建的Snord116del小鼠模型表现出贪食和血液Ghrelin升高等PWS症状。此次研究中,我们繁育野生型(WT)、Snord116del(SW)、Ghrl-/-(WG)、Ghsr-/-(WR)小鼠,并制备[Snord116del,Ghrl-/-](SG)和[Snord116del,Ghsr-/-](SR)双敲除小鼠,对其生长发育 ...
甘利芬
core  

Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin   +4 more
wiley   +1 more source

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie   +2 more
wiley   +1 more source

Hepatitis E Virus Infection Status and New Infection Rate Study of Patients with Maintenance Haemodialysis [PDF]

open access: yes, 2016
目的 明确厦门市维持性血液透析患者戊型肝炎病毒感染现状,探究该人群中戊型肝炎病毒新发感染情况,并分析可能的危险因素,为戊型肝炎的一、二级预防提供参考依据。 方法 2014年8月至2015年5月,研究对象为厦门大学附属中山医院肾内科血液透析室进行维持性血液透析治疗的患者218人,选择同期在该医院体检中心进行健康体检的体检者218人作为对照人群,排除标准为具有血透史、器官移植史和先天性/获得性免疫功能缺陷,匹配条件为年龄和性别。采用病例对照研究设计,以问卷调查的方式收集调查对象的一般资料,以酶联免疫法 ...
陈迪
core  

Recommendations for dealing with waste contaminated with Ebola virus: a Hazard Analysis of Critical Control Points approach [PDF]

open access: yes, 2016
Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks.
Ahmed A Mohamedani   +25 more
core   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

Influence of Traditional Chinese Medicine emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease (中医情志护理干预对终末期肾病透析患者心理及生活质量的影响研究)

open access: yes中西医结合护理
Objective To investigate the influence of Traditional Chinese Medicine (TCM) emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease.
JIA Hengxia (贾恒霞)   +2 more
doaj   +1 more source

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