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Se pu = Chinese journal of chromatography, 2021 外泌体是由各种类型细胞在正常或非正常生理情况下分泌释放至细胞外且携带多种生物活性分子的细胞外囊泡,在细胞间通讯和免疫应答等生物过程中发挥着重要作用。肝内胆管癌是一种胆道上皮恶性肿瘤,早期无明显临床症状且生存率较低,目前常用的诊断手段包括依赖于影像设备的诊断方式和灵敏度及特异性较低的诊断标志物等,这些手段的不足对发展新的特异性标志物提出了需求。该文对血清中的外泌体进行了分离和表征,并采用液相色谱-质谱技术针对健康组与肝内胆管癌患者组的血清样本和血清外泌体样本进行了无标记定量蛋白质组学分析 ...
Kaige Yang +3 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 2011 【目的】 探讨白细胞介素-17(IL-17)和白细胞介素-23(IL-23)在变应性鼻炎患者血清中的表达及其与血清特异性IgE的相关性【方法】 研究对象分为变应性鼻炎组(24例)和正常对照组(12例)，分别收集受试者的血清，采用瑞典Pharmacia公司UniCAP 100E全自动免疫荧光定量分析系统检测常见吸入性变应原血清特异性IgEELISA法检测血清中IL-17和IL-23表达情况【结果】12例正常对照组者血清sIgE结果均为0级，24例变应性鼻炎患者血清sIgE的浓度为2 ~ 6级IL ...
doaj +1 more source
Lughawiyah: Journal of Arabic Education and Linguistics, 2022 The purpose of this study is to determine the motivation of non-madrasa graduate students to learn Arabic at Department of Arabic Language Education of IAIN Kendari. The type of this research was descriptive qualitative in which data were collected by observation, interview, and documentation.
Rachmad Ramadhan, Kamilatul Ubudiyah
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血清 miR-210 和 miR-375 在非小细胞肺癌患者中的表达变化情况
, 2020 目的：观察非小细胞癌患者中血清 miR-210 和 miR-375 的表达情况。方法：选取 2019 年 5 月至 2020 年 5 月于邯郸市第一医院就诊的 50 例经病理确诊为非小细胞肺癌的患者，将其纳入试验中作为观察组；选取同期于邯郸市第一医院接受体检且正常者 50 例，将其纳入试验中作为对照组。提取研究对象的血清总 RNA，并检测其血清 miR-210 和 miR-375。结果：观察组 miR-210、miR-375 表达量均高于对照组，两组血清中的 miR-210 和 miR-375 ...
朱 会利
semanticscholar +1 more source
高通量固相萃取-超高效液相色谱-串联质谱法测定血清中17种全氟/多氟烷基化合物
Se pu = Chinese journal of chromatography全氟烷基和多氟烷基化合物(PFASs)因其持久性、毒性和容易富集等特点,成为国内外广泛关注的一类新污染物。开展人体内PFASs的生物监测和暴露评估对于评估这些化学物质对人体健康的风险具有重要意义。因此亟需开发准确灵敏、方便快捷的检测方法。本研究采用自制的不需要活化、平衡的直通式HMR固相萃取柱净化样本,结合超高效液相色谱-串联质谱(UHPLC-MS/MS),建立了血清中17种PFASs的检测方法。50 μL血清样本在HMR固相萃取柱中用400 μL乙腈提取(每次200 μL)并净化2次后 ...
Qiang Lin +7 more
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Se pu = Chinese journal of chromatography本研究以我国中部地区某市60名普通成人为研究对象,采用固相萃取结合气相色谱-串联质谱技术(SPE-GC-MS/MS)同时测定人血清样品中97种典型化学污染物的浓度,采用多元线性回归模型分析人口学特征、生活习惯和饮食对血清中化学污染物浓度的影响,结合已知的生物监测当量(BEs)和人类生物监测(HBM)值计算危害商(HQ)和危害指数(HI)来评估化学污染物单一和累积暴露的健康风险。结果表明,在人体血清中主要检出的污染物为有机氯农药(OCPs)、多氯联苯(PCBs)及多环芳烃(PAHs),其中六氯苯(100 ...
Mingye Zhang +8 more
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Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 2, Page 256-269, August 2026.ABSTRACT Objectives The primary aims of this study were to validate externally the diagnostic performance of the Assessment of Different NEoplasias in the adneXa (ADNEX) model for distinguishing between malignant and benign adnexal masses, when used by non‐expert ultrasound examiners in general gynecological settings with a low prevalence of ovarian ...
I. M. Dueholm Hjorth +11 more
wiley +1 more source
People and Nature, Volume 8, Issue 7, Page 2338-2352, July 2026.Abstract Urbanisation is reshaping how people experience wildlife, reducing our shared spaces with local biodiversity. Fewer opportunities for human–wildlife interactions weaken our emotional attachments to nature and precipitate a loss of species knowledge and familiarity.
Sam S. S. Lau +3 more
wiley +1 more source
维持性血液透析患者血清低氧诱导通路相关指标水平与肾性贫血的相关性
Zhongguo shiyan zhenduanxue, 2020 目的研究维持性血液透析(MHD)患者血清低氧诱导通路相关指标表达水平与肾性贫血相关因素分析。方法选取2019年1月-2020年1月于吉林大学第二医院血液净化中心行规律血液透析治疗的MHD患者,根据血红蛋白(Hb)水平及是否应用促红细胞生成素(EPO)分为4组:EPO应答组、EPO低应答组、无贫血组、贫血未治疗组。采用双抗体夹心酶联免疫吸附法测定MHD患者的血清铁调素(Hepcidin)、低氧诱导因子1α(HIF-1α)、低氧诱导因子2α(HIF-2α)、脯氨酰羟化酶(PHD)的表达水平 ...
王金鑫 +5 more
doaj
Enhanced Dual‐Modality CT Imaging for Evaluating Hematogenous Metastasis During Photothermal Therapy
Rare Metals, Volume 45, Issue 7, July 2026.Dual‐modality computed tomography (CT) nanoprobes, BPP, are developed for real‐time microscopic monitoring of microvessel morphology and vascular permeability to provide predictive insights into cancer progression and metastasis. ABSTRACT Dynamic assessment of hematogenous metastasis is crucial for the tumor during photothermal therapy.
Yanhong Sun +7 more
wiley +1 more source