Optimization of the extraction process of ACE inhibitory peptides from distillery waste and their antioxidant activity [PDF]
ObjectiveThis study aimed to handle distillery waste effectively, research and develop high-value components within distillery waste, and explore its potential application approaches.MethodsProteins were extracted from distillery waste throuth the ...
DONG Liang +3 more
core +1 more source
Selection of Angiotensin I Converting Enzyme Inhibitory Peptides from Enzymatic Hydrolysate of Pinctada martensii Using Surface Plasmon Resonance [PDF]
Surface plasmon resonance (SPR) technology was used to analyze the binding of the three ultrafiltration fractions of the protein hydrolysate of Pinctada martensii (PHPM) with angiotensin I converting enzyme (ACE) as a protein ligand.
XIA Xiaoyu, WEN Caixing, CAO Wenhong, QIN Xiaoming, LI Yujin, LIN Haisheng, CHEN Zhongqin, ZHENG Huina, ZHU Guoping, GAO Jialong
core +1 more source
Optimization of the preparation process of hypotensive peptide of Agrocybe cylindracea [PDF]
ObjectiveThis study aimed to determine the optimal extraction process for antihypertensive peptide from Agrocybe cylindracea to achieve higher yield and enhanced activity.MethodsWith the polypeptide yield and ACE inhibition rate as the evaluation index ...
KANG Jingjing +3 more
core +1 more source
The study on the mechanism of topical propranolol gel in therapy of superficial infantile hemangiomas [PDF]
, 2015 目的：探讨外涂普萘洛尔凝胶对浅表型婴幼儿血管瘤（IHs）患儿血浆碱性成纤维生长因子（bFGF）、基质金属蛋白酶-9(MMP-9)、血管内皮生长因子（VEGF）、肾素和血管紧张素Ⅱ（ATⅡ）水平的影响。初步探讨普萘洛尔凝胶治疗婴幼儿血管瘤的可能机制，以寻找治疗婴幼儿血管瘤高选择性用药，减少不良反应的发生。 方法：选取2013年2月至2014年2月厦门大学附属东方医院普通外科接受普萘洛尔凝胶治疗的33例婴幼儿血管瘤患儿，采用Achauer分级标准评估疗效，酶联免疫吸附试验（ELISA）检测患儿治疗前 ...
唐玉娟
core
Research progress on ACE immobilization and immobilized ACE used for affinity separation and enrichment of food-derived antihypertensive peptides [PDF]
Food-derived ACE inhibitory peptides can regulate blood pressure mildly and specifically by inhibiting the activity of ACE, which has attracted widespread attention and extensive research.
LIU Zhiyu, ZHANG Jingjing
core +1 more source
Zhongguo shiyan zhenduanxue, 2003 目的 探讨儿童持续性蛋白尿与血管紧张素转换酶基因多态性的关系。方法 用PCR方法检测了 186例儿童持续性蛋白尿患儿ACE基因多态性及ACE基因多态性与尿蛋白量、血尿、高血压、氮脂血症的关系。结果 持续性蛋白尿患儿ACE -DD基因频率为 0 .2 0 ,II基因频率为 0 .5 2 ,DI基因频率为 0 .2 8;持续性蛋白尿患儿ACE基因多态性与正常对照组存在明显差异 ;尿蛋白量与ACE基因多态性有关 ,大量蛋白尿多为ACE -II型 ;在紫癜性肾炎组血尿的发生以II型为主 ...
李丽红 +16 more
doaj
Zhongguo shiyan zhenduanxue, 2003 目的 探讨儿童持续性蛋白尿与血管紧张素转换酶基因多态性的关系。方法 用PCR方法检测了 186例儿童持续性蛋白尿患儿ACE基因多态性及ACE基因多态性与尿蛋白量、血尿、高血压、氮脂血症的关系。结果 持续性蛋白尿患儿ACE -DD基因频率为 0 .2 0 ,II基因频率为 0 .5 2 ,DI基因频率为 0 .2 8;持续性蛋白尿患儿ACE基因多态性与正常对照组存在明显差异 ;尿蛋白量与ACE基因多态性有关 ,大量蛋白尿多为ACE -II型 ;在紫癜性肾炎组血尿的发生以II型为主 ...
李丽红 +5 more
doaj
The effect of pentosan polysulfate on diabetic nephropathy renal tubular epithelial cells injury through regulating p38 MAPK signaling pathway [PDF]
, 2016 目的：观察戊糖多硫酸钠是否通过调控P38MAPK干预糖尿病肾病肾小管上皮细胞的损伤。方法：利用不同浓度（10mmol/L～50mmol/L）葡萄糖刺激肾小管上皮细胞（HK-2）48h，应用CCK-8比色法检测肾小管上皮细胞增殖的改变。利用不同时间段（0h～48h）葡萄糖刺激细胞，用Westernblot法检测P38MAPK蛋白的表达水平。分为正常对照组（control组）、高糖组（HG组，葡萄糖30mmol/L)、戊糖多硫酸钠（PPS）组（PPS200µg/mL)、高糖＋戊糖多硫酸钠组（HG＋
张天英
core
应用PCR-RFLP方法检测新生儿HIE患儿的ACE基因多态性
Zhongguo shiyan zhenduanxue, 2005 目的探讨新生儿缺氧缺血性脑病与血管紧张素转换酶基因多态性的相关性。方法设新生儿缺氧缺性脑病患儿为观察组,正常新生儿为对照组。分别提取外周血白细胞DNA,然后用ACE引物进行聚合酶链反应（PCR）,对产物进行电泳,根据限制性片段长度多态性（RFLP）所致不同的迁移率判断基因型。结果检测出ACE基因分为DD、ID、II三种类型。观察组与对照组ACE基因型分布频率不同,观察组ACE基因型以DD型为主,与对照组比较 ...
赵宏霞 +4 more
doaj
Zhongguo shiyan zhenduanxue, 2017 绝经是女性随着年龄增长,卵巢功能衰退,雌激素分泌缺乏的自然进程。在绝经前,与男性相比,女性的雌激素可通过改善血脂和载脂蛋白代谢,调节冠状动脉的舒缩反应及减缓血管紧张素转换酶（ACE）的活性而对血管内皮细胞起保护作用,心血管疾病（CVD）的发病率较男性明显低[1 ...
吴燕, 李晓微, 冯朝辉, 何敏
doaj