Results 11 to 20 of about 3,519 (130)

Effect of dipeptidyl peptidase‐4 inhibitor on the progression of coronary artery disease evaluated by computed tomography in patients receiving insulin therapy for type 2 diabetes mellitus DPP‐4抑制剂对接受胰岛素治疗的2型糖尿病患者冠状动脉疾病进展的影响

open access: yesJournal of Diabetes, Volume 15, Issue 11, Page 944-954, November 2023., 2023
Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Young Choi   +4 more
wiley   +1 more source

Associations of blood biomarkers with arterial stiffness in patients with diabetes mellitus: A population‐based study 糖尿病患者血液生物标志物与动脉硬化的关系: 一项基于人群的研究

open access: yesJournal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023
Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang   +9 more
wiley   +1 more source

Effect of DBP inhibition on vascular calcification in chronic uremic rats [PDF]

open access: yes, 2022
Objective To evaluate the effect of D-site binding protein (DBP) inhibition on vascular calcification in chronic uremic rats. Methods GSE146638 was downloaded from the public database (Gene Expression Omnibus, GEO), and a total of 10 samples from rat of ...
Cao Sujuan, Liu Shuzheng, Yuan Buqi, Yuan Peile, Zhao Songhe, Zhang Yunfang
core   +1 more source

Stress hyperglycemia ratio is associated with systemic inflammation and clinical outcomes in diabetic inpatients with pneumonia on admission 糖尿病合并肺炎住院患者的应激性高血糖率与全身性炎症和临床结局相关

open access: yesJournal of Diabetes, Volume 15, Issue 7, Page 545-556, July 2023., 2023
Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
wiley   +1 more source

Cilostazol treatment for preventing adverse cardiovascular events in patients with type 2 diabetes and coronary atherosclerosis: Long‐term follow‐up of the ESCAPE study 西洛他唑治疗预防2型糖尿病合并冠状动脉粥样硬化患者不良心血管事件:ESCAPE研究的长期随访

open access: yesJournal of Diabetes, Volume 14, Issue 8, Page 524-531, August 2022., 2022
Highlights In this ESCAPE‐extension study, cilostazol treatment reduced the incidence of adverse cardiovascular events in patients with type 2 diabetes when compared with aspirin for a 5.2‐year median follow‐up. During the follow‐up period, no adverse events were noted in the cilostazol group that exceeded those in the aspirin group.
Minji Sohn, Eun Ju Chun, Soo Lim
wiley   +1 more source

Application of non-invasive methods of radiology to the osteoporosis [PDF]

open access: yes, 2023
Early screening and timely treatment can effectively reduce the morbidity and mortality of the osteoporotic fractures, and hence efficient and accurate non-invasive radiological method is crucial.
LIU Chenjun   +3 more
core   +1 more source

Coronary angiography review in 21 children with Kawasaki disease complicated with coronary artery disease [PDF]

open access: yes, 2023
Objective·To analyze the progression of children with severe coronary artery lesions due to Kawasaki disease by coronary artery angiography, and evaluate the diagnostic value of echocardiography in these children.Methods·A retrospective analysis was ...
CUI Qing   +5 more
core   +1 more source

Effect of phosphate binders on serum FGF-23 levels in maintenance hemodialysis patients with hyperphosphatemia [PDF]

open access: yes, 2014
目的:近年来,许多研究显示高水平的FGF-23与肾脏疾病进展、心血管病死率及左心室肥厚相关。饮食磷限制及磷结合剂可用来控制磷酸盐平衡及升高的血清FGF-23水平。本研究的目的在于比较碳酸镧和碳酸钙对于维持性血液透析高磷血症患者血清FGF-23水平的影响。 方法:选取56例在我科行维持性血液透析治疗的慢性肾功能衰竭患者,所有患者维持性血液透析治疗超过3个月,接受血液透析治疗3次/周,每次4h,碳酸氢盐透析液钙离子浓度为2.5mEq/L。研究期间,患者的血液透析治疗方案保持不变。入选患者符合血磷>1 ...
郭晓丹
core   +2 more sources

老年性骨质疏松和血管钙化的相关性 [PDF]

open access: yes, 2018
老年性骨质疏松和血管钙化均为衰老伴行的退行性疾病,是老龄化社会主要的健康问题之一。近年来大量研究表明,老年性骨质疏松和血管钙化的发生呈正相关。现从流行病学、危险因素、发病机制和临床治疗等方面对二者的相关性逐一综述,从而为进一步的机制研究及临床诊治提供一定的理论参考依据,并寻找新的治疗靶点。福建省自然科学基金 ...
徐军霞, 杨娜
core   +1 more source

TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells [PDF]

open access: yes, 2016
溶血卵磷脂(lysophosphatidylcholine,lysoPC)是氧化低密度脂蛋白(oxidizedlow-densitylipoprotein,ox-LDL)的主要成分。早期的研究表明,lysoPC可诱导人冠状动脉平滑肌细胞(humancoronaryarterysmoothmusclecells,HCASMCs)凋亡,但具体机制尚不清楚。近期,我们通过细胞活力测定,流式细胞术,共聚焦显微镜及分子生物学手段对lysoPC作用的分子机制进行研究发现,lysoPC可引发细胞外钙离子内流 ...
王渊
core   +1 more source

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