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Journal of Diabetes, Volume 15, Issue 11, Page 944-954, November 2023., 2023 Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Young Choi +4 more
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Journal of Diabetes, Volume 15, Issue 10, Page 853-865, October 2023., 2023 Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang +9 more
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Journal of Diabetes, Volume 15, Issue 7, Page 545-556, July 2023., 2023 Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
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Journal of Diabetes, Volume 14, Issue 8, Page 524-531, August 2022., 2022 Highlights In this ESCAPE‐extension study, cilostazol treatment reduced the incidence of adverse cardiovascular events in patients with type 2 diabetes when compared with aspirin for a 5.2‐year median follow‐up. During the follow‐up period, no adverse events were noted in the cilostazol group that exceeded those in the aspirin group.
Minji Sohn, Eun Ju Chun, Soo Lim
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Linchuang shenzangbing zazhi, 2014 目的 观察慢性肾脏疾病(chronic kidney disease,CKD)3期开始纠正钙磷代谢紊乱对患者血管钙化的影响。方法 选择本院门诊或住院的CKD 3～4期非透析患者80例,按随机数字表法分为干预组及观察组,每组40例。干预组进行钙磷代谢紊乱严格干预,观察组则给予CKD的常规治疗,观察并比较2组患者的血压、血尿素氮、血肌酐、血钙、血磷、全段甲状旁腺素(intact parathyroid hormone,iPTH)、血红蛋白(hemoglobin,Hb)、血白蛋白等指标,同时通过腹部、骨盆 ...
张新
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Zhongshan Daxue xuebao. Yixue kexue ban, 2019 【目的】探讨吴茱萸次碱对血管平滑肌细胞钙化的作用及机制。【方法】本研究采用大鼠血管平滑肌细胞钙化体外模型，用不同浓度的吴茱萸次碱处理细胞，qRT-PCR检测成骨样分化基因Runx2、BMP2和Osterix的表达和茜素红染色测细胞钙化程度。此外，观察吴茱萸次碱对血管平滑肌细胞Sirt1表达水平的影响以及Sirt1抑制剂对细胞钙化的影响。【结果】茜素红素染色及钙离子浓度定量实验均显示不同浓度的吴茱萸次碱可明显地改善高磷高钙诱导的大鼠血管平滑肌细胞的钙化程度（136±10、75±6、52±6、31±5 ...
邵静, 陈安, 张秀丽, 杨平珍
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Zhongguo shiyan zhenduanxue, 2022 转移性钙化(metastatic calcification,MC)是由于全身性的钙、磷代谢障碍,引起机体血钙或血磷升高,导致钙盐在未受损伤的组织内沉积,随血液循环异位于肾小管、肺泡壁等软组织或血管壁。转移性肺钙化(metastatic pulmonary calcification,MPC)是钙在肺组织中沉积,继发于无肺软组织损伤史的钙代谢异常。最常见的原因为慢性肾功能衰竭,血液透析,器官移植术后,原发性或继发性甲状旁腺功能亢进症,破坏性骨损害等[1-5]。发病率低,国内外报道以个案病例为主 ...
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Linchuang shenzangbing zazhi, 2016 流行病学资料显示,血管钙化与慢性肾脏病(chronic kidney disease,CKD),尤其是维持性透析患者心血管疾病的患病率和病死率密切相关。过氧化物酶体增殖物活化受体γ(peroxisome proliferator-activated receptor gamma,PPARγ)是许多生理和疾病的重要调节因子。近来有研究表明PPARγ通过调节间充质干细胞和造血干细胞在体内骨量稳态中起着双重调节作用 ...
高敏, 毛慧娟
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Linchuang shenzangbing zazhi, 2021 慢性肾脏病-矿物质和骨异常（chronic kidney disease mineral and bone disorder,CKD-MBD）是尿毒症常见而严重的并发症之一。CKD-MBD引起皮下组织和肢端动脉的中层钙化及内膜增生,导致的皮肤坏死和肢端坏疽,即为钙化防御[1],又称钙性尿毒症性小动脉病,是一种少见的、严重的、以系统性小动脉钙化和组织缺血坏死为特征的疾病[2]。在全球透析患者中发病率约1/10 000[3],美国透析患者中发病率约35/10 000[4],严重者可出现坏疽 ...
Zhu Ying +4 more
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Zhongguo shiyan zhenduanxue, 2005 目的 探讨肺硬化性血管瘤 （PulmonarySclerosingHemangioma ,PSH）的CT影像诊断特点。方法 经手术病理证实的 5例肺硬化性血管瘤 ,全部行CT检查。结果 肺硬化性血管瘤CT表现为密度均匀的孤立软组织肿块或结节 ,部分可有浅分叶 ,少数可有沙砾状钙化 ,纵隔、肺门未见异常肿大淋巴结。结论 CT对肺硬化性血管瘤的诊断和鉴别诊断更有价值。
赵素岗 +5 more
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