Results 11 to 20 of about 3,519 (130)
Highlights Preclinical data showed that dipeptidyl peptidase‐4 inhibitors (DPP‐4is) may prevent insulin‐induced atherosclerosis. In patients treated with insulin for type 2 diabetes who underwent ≥2 serial coronary computed tomography angiographies(CCTA), a new obstructive coronary artery disease (OCAD) was less developed on the follow‐up CCTA in those
Young Choi +4 more
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Highlights Few studies have investigated the association of large‐scale biomarkers and pulse wave velocity (PWV) among diabetic patients. This study investigates the relationships of serum laboratory tests with PWV and explored the associations between PWV and all‐cause mortality among diabetic patients.
Yong‐Qi Liang +9 more
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Effect of DBP inhibition on vascular calcification in chronic uremic rats [PDF]
Objective To evaluate the effect of D-site binding protein (DBP) inhibition on vascular calcification in chronic uremic rats. Methods GSE146638 was downloaded from the public database (Gene Expression Omnibus, GEO), and a total of 10 samples from rat of ...
Cao Sujuan, Liu Shuzheng, Yuan Buqi, Yuan Peile, Zhao Songhe, Zhang Yunfang
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Highlights High stress hyperglycemia ratio (SHR) was associated with elevated systematic inflammation in diabetic inpatients with pneumonia on admission. In the absence of hypoglycemia on admission, SHR was of J‐shaped associations with adverse clinical outcomes in diabetic inpatients with pneumonia of different severity.
Bing Liu, Yu Chen, Liping Yu, Min Zhou
wiley +1 more source
Highlights In this ESCAPE‐extension study, cilostazol treatment reduced the incidence of adverse cardiovascular events in patients with type 2 diabetes when compared with aspirin for a 5.2‐year median follow‐up. During the follow‐up period, no adverse events were noted in the cilostazol group that exceeded those in the aspirin group.
Minji Sohn, Eun Ju Chun, Soo Lim
wiley +1 more source
Application of non-invasive methods of radiology to the osteoporosis [PDF]
Early screening and timely treatment can effectively reduce the morbidity and mortality of the osteoporotic fractures, and hence efficient and accurate non-invasive radiological method is crucial.
LIU Chenjun +3 more
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Coronary angiography review in 21 children with Kawasaki disease complicated with coronary artery disease [PDF]
Objective·To analyze the progression of children with severe coronary artery lesions due to Kawasaki disease by coronary artery angiography, and evaluate the diagnostic value of echocardiography in these children.Methods·A retrospective analysis was ...
CUI Qing +5 more
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Effect of phosphate binders on serum FGF-23 levels in maintenance hemodialysis patients with hyperphosphatemia [PDF]
目的:近年来,许多研究显示高水平的FGF-23与肾脏疾病进展、心血管病死率及左心室肥厚相关。饮食磷限制及磷结合剂可用来控制磷酸盐平衡及升高的血清FGF-23水平。本研究的目的在于比较碳酸镧和碳酸钙对于维持性血液透析高磷血症患者血清FGF-23水平的影响。 方法:选取56例在我科行维持性血液透析治疗的慢性肾功能衰竭患者,所有患者维持性血液透析治疗超过3个月,接受血液透析治疗3次/周,每次4h,碳酸氢盐透析液钙离子浓度为2.5mEq/L。研究期间,患者的血液透析治疗方案保持不变。入选患者符合血磷>1 ...
郭晓丹
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老年性骨质疏松和血管钙化均为衰老伴行的退行性疾病,是老龄化社会主要的健康问题之一。近年来大量研究表明,老年性骨质疏松和血管钙化的发生呈正相关。现从流行病学、危险因素、发病机制和临床治疗等方面对二者的相关性逐一综述,从而为进一步的机制研究及临床诊治提供一定的理论参考依据,并寻找新的治疗靶点。福建省自然科学基金 ...
徐军霞, 杨娜
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TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells [PDF]
溶血卵磷脂(lysophosphatidylcholine,lysoPC)是氧化低密度脂蛋白(oxidizedlow-densitylipoprotein,ox-LDL)的主要成分。早期的研究表明,lysoPC可诱导人冠状动脉平滑肌细胞(humancoronaryarterysmoothmusclecells,HCASMCs)凋亡,但具体机制尚不清楚。近期,我们通过细胞活力测定,流式细胞术,共聚焦显微镜及分子生物学手段对lysoPC作用的分子机制进行研究发现,lysoPC可引发细胞外钙离子内流 ...
王渊
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