Results 21 to 30 of about 3,519 (130)

Protection Effect of Exogenous Fibroblast Growth Factor 21 on the Kidney Injury in Vascular Calcification Rats [PDF]

open access: yes, 2018
Background: Chronic kidney disease (CKD) is closely related to the cardiovascular events in vascular calcification (VC). However, little has known about the characteristics of kidney injury caused by VC.
Cheng, Shu-Juan   +8 more
core   +3 more sources

Application status of cell models in clinical nutrition research [PDF]

open access: yes, 2020
Traditional clinical nutrition research mostly stay at the stage of human and animal experiments. Cell model experiment has gradually become an important way in clinical nutrition research nowadays.
Jian HUANG   +4 more
core   +1 more source

Guidelines for breast cancer diagnosis and treatment by China Anti-cancer Association (2024 edition) [PDF]

open access: yes, 2023
According to the latest data released by the International Agency for Research on Cancer of the World Health Organization (WHO), breast cancer has become the malignant tumor with the highest incidence rate around the world, seriously endangering the ...
The Society of Breast Cancer China Anti-Cancer Association, Breast Oncology Group of the Oncology Branch of the Chinese Medical Association
core   +1 more source

颅内椎动脉与基底动脉血管钙化在CTA上的分布比较 Comparison of Calcification Distribution in Intracranial Vertebral Artery and Basilar Artery on CTA

open access: yesZhongguo cuzhong zazhi, 2018
目的 比较颅内椎动脉与基底动脉血管钙化在计算机断层扫描血管成像(computed tomography angiography,CTA)上的发生率和分布特点。 方法 连续收集2014年2月-2017年10月在本院住院并行头颈部CTA检查的患者资料,通过综合分析 CTA影像资料,比较血管钙化在颅内椎动脉和基底动脉发生率的差异及其在近、远段发生率的差异。 结果 共收集患者93例,其中男64例,女29例,平均年龄(62.8±12.9)岁。血管钙化组的平均年龄 (68.8±10.4)岁,明显高于无血管钙化组的 ...
刘奇,朱先进,赵志强,赵宇,金旻,刘洋,杜彬
doaj   +1 more source

维持性血液透析患者血清OPN和iPTH水平与血管钙化的相关性研究

open access: yesZhongguo shiyan zhenduanxue, 2021
心血管并发症是维持性血液透析(MHD)患者首要的死亡原因,其血管相关性研究已经成为热点[1-2]。血清骨桥蛋白(OPN)、血清全段甲状旁腺素(iPTH)的变化可能参与了维持性血液透析(MHD)患者的血管钙化发生发展,本研究通过观察血清OPN、iPTH、钙、磷等指标与MHD患者血管钙化程度的关系,旨在探讨MHD患者血管钙化的可能诱发因素,报道如下。
王颜   +8 more
doaj  

早期慢性肾脏病患者体内血清白蛋白水平对冠脉钙化的预测价值 [PDF]

open access: yes
目的探讨早期慢性肾脏病(CKD)患者的血清白蛋白水平与冠脉钙化(CAC)的相关性,以及对CAC发生及严重程度的预测价值。方法筛选2019年1月至2022年12月于中山大学孙逸仙纪念医院住院行冠状动脉CTA检查的早期CKD患者391例,收集一般临床资料、血清学检查结果、冠脉CTA检查结果。根据冠脉钙化积分(CACS)将患者分为非冠脉钙化组(CACS=0分)184例,冠脉钙化组(CACS>0分)207例;根据血清白蛋白水平分为三组,即白蛋白<35 g/L组(30例)、35 g/L≤白蛋白< ...
伍卫   +4 more
core   +4 more sources

Progress of HIF-1α and HIF-PHI in vascular calcification of chronic kidney disease [PDF]

open access: yes
Chronic kidney disease has become a major global public health challenge, and cardiovascular disease is the leading cause of death. Vascular calcification is characterized by pathological deposition of calcium and phosphate minerals in the arterial wall,
LI Xiangyou   +4 more
core   +1 more source

Effects of Cinacalcet HCl on Secondary Hyperparathyroidism and Renal Injury in the Uremic Rat [PDF]

open access: yes, 2016
目的 慢性肾脏病患者随着肾脏功能的逐渐减退,早期即可出现钙磷失衡、维生素D缺乏、甲状旁腺激素以及成纤维生长因子FGF23的升高,而这种矿物质代谢紊乱又可促使患者出现继发性甲状旁腺功能亢进以及加重肾脏损伤。目前CaSR激动剂作为有效抑制甲状旁腺增生的临床药物,适用于已发生SHPT的透析患者,为探究其是否也能防治继发性甲状旁腺亢进、矿物质代谢紊乱及肾脏损伤,本研究通过5/6肾大部切除术结合高磷饮食建立尿毒症大鼠模型,分别在造模成功早期预防性给予大鼠西那卡塞干预以及在大鼠慢性肾衰确立后给予盐酸西那卡塞干预 ...
孙青宜
core  

冠脉CT血管造影对急性下壁心肌梗死罪犯血管的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2023
目的 探究冠状动脉CT血管造影(CTA)对急性下壁心肌梗死(AIMI)罪犯血管的诊断价值。方法 选取成都市第三人民医院2019年1月到2021年12月收治的109例疑似AIMI患者,以数字减影血管造影(DSA)诊断结果作为“金标准”,对比分析CTA对AIMI罪犯血管的检出情况及不同罪犯血管的诊断价值。结果 入组患者经临床诊断及冠状动脉造影术检查确诊为AIMI者99例,CTA诊断AIMI患者敏感度为93.94%(93/99),特异度为80.00%(8/10),准确率为92.66%(101/109 ...
陈旖旎, 童琳, 崔彩艳
doaj  

血液透析滤过对终末期肾病患者钙磷代谢及心血管并发症的影响

open access: yesZhongguo shiyan zhenduanxue, 2023
目的 探讨血液透析滤过对终末期肾病患者钙磷代谢及心血管并发症发生的影响。方法 选取2021年1月至2022年1月我院收治的60例终末期肾病血液透析患者,将每周两次血液透析患者设为HD组,每周两次血液透析联合每两周一次血液透析滤过患者设为HDF组。比较两组患者治疗前后钙磷代谢指标变化及心血管并发症发生情况。结果 治疗后,两组患者血钙(Ca)、血磷(P)、甲状旁腺激素(iPTH)水平均较治疗前改善,差异有统计学意义 ...
张帆, 江杨, 龚宇, 罗逊
doaj  

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