Zhongguo shiyan zhenduanxue, 2019 肥胖相关性肾小球病(ORG)发病率随超重及肥胖人群增加而逐年上升,其发病可能与肥胖引起的血流动力学改变、RAAS激活、胰岛素抵抗、脂质异常沉积、炎症相关,进一步导致线粒体氧化应激和细胞因子异常分泌,促进ORG进展。临床上主要表现为缓慢进展的蛋白尿,伴或不伴血尿 ...
温蕊, 周广宇, 赵圆圆, 郭建蕾
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Zhongguo shiyan zhenduanxue, 1998 目的为筛选与糖尿病肾病（ＤＮ）有关的危险因素，并了解各因素在ＤＮ发病中各自独立的作用及相对影响大小。方法采用多元逐步回归的统计方法对１０６例Ⅱ型糖尿病（ＤＭ）患者的临床及生化指标进行分析。结果①存在微量白蛋白尿的患者占总病例数的３０．１％；②Ⅱ型ＤＭ合并异常白蛋白尿组和正常白蛋白尿组相比，前组年龄、病程、体重指数、空腹Ｃ－肽、ａｐｏＢ１００和Ｌｐ（ａ）均高于后组；③与ＤＮ相关的危险因素依次为ａｐｏＢ１００、舒张压、空腹血糖、餐后２ｈＣ－肽、病程、年龄、Ｌｐ（ａ）和餐后２ｈ胰岛素。结论血脂异常、高血压 ...
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