Results 101 to 110 of about 209,042 (243)

Representation of obligate groundwater‐dwelling copepod diversity in European protected areas

open access: yesConservation Biology, EarlyView.
Abstract Groundwaters sustain diverse surface ecosystems and are populated by metazoan species, mostly invertebrates, that provide fundamental ecological functions and are often of prominent conservation value due to narrow endemism and high phylogenetic rarity.
Francesco Cerasoli   +7 more
wiley   +1 more source

Her-2/neu和CD138在乳腺癌中表达及意义

open access: yesZhongguo shiyan zhenduanxue, 2013
目的检测乳腺癌组织中Her-2/neu和CD138的表达情况,探讨二者在乳腺癌中表达的意义和相互关系。方法应用免疫组化方法(S-P法)观察102例乳腺癌,30例乳腺良性病变组织(15例乳腺良性肿瘤与15例正常乳腺组织)Her-2/neu和CD138的表达。结果①102例乳腺癌组织和30例乳腺良性病变组织中Her-2/neu阳性表达率分别为58%和0%,CD138阳性表达率分别为41%-42%和100%。乳腺癌组织中Her-2/neu阳性表达率显著高于其在良性病变组织的阳性表达率 ...
陈军, 胡永均, 张桃华, 陈玲玲
doaj  

Study on the effects of down-regulating Annexin A3 expression on biological behaviors of lung adenocarcinoma and its molecular mechanism [PDF]

open access: yes, 2015
肺癌是我国第一大癌症,其发病率和死亡率均居恶性肿瘤之首,严重危害人类健康。肺癌按组织学类型可分为鳞癌、腺癌、小细胞癌和大细胞癌。近年来,肺腺癌(lungadenocarcinoma,AdC)的发病率呈逐步上升趋势,且患者死亡率高、预后极差。癌细胞易转移是肺腺癌患者预后差的主要原因,因此,探寻肺腺癌转移的分子机制及其新的治疗靶标,对于提高肺腺癌患者预后意义重大。我们前期研究中,采用定量蛋白质组学技术鉴定出AnnexinA3(Anxa3)为一个新的肺腺癌转移相关分子 ...
刘青青
core  

Calibration of the species threat abatement and restoration metric's threat abatement component in a Costa Rican landscape

open access: yesConservation Biology, EarlyView.
Abstract Achieving global conservation policy goals requires the ability to set and measure progress toward science‐based targets for biodiversity. The species threat abatement and restoration (STAR) metric was developed to enable actors to set science‐based targets for species.
Louise Mair   +17 more
wiley   +1 more source

大肠癌原发灶及粪便标本中基因mRNA表达及其临床意义

open access: yesZhongguo shiyan zhenduanxue, 2012
目的通过对COX-2,CK-20,CD44v6mRNA在结直肠原发灶及病人粪便中的表达,证实粪便中COX-2,CK-20,CD44v6mRNA表达来源于原发灶肿瘤细胞的脱落所致,为临床结直肠癌筛查选择合适的多基因标记物联合检测指标。方法对38例行结肠癌根治术的病人,原发灶及术前收集的粪便标本采用RT-PCR技术对COX-2,CK-20,CD44v6mRNA表达进行检查。结果研究发现,COX-2mRNA在原发灶及粪便中同时阳性表达率为44.7%(17/38),同时阴性表达率为39.5%(15/38 ...
赵金伟   +4 more
doaj  

Expression and Significance of gp96 and Immune-related Gene CTLA-4, CD8 in Lung Cancer Tissues [PDF]

open access: yes, 2010
Background and objective It has been proven that gp96 plays an important role in specific cytotoxic immune response which is involved in anti-tumor effect in the body.
Haiyan ZHENG   +4 more
core  

Attainment Pairing Effects on Cognitive Conflict in Technology‐enhanced EFL Cooperative Tasks

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This study examines how attainment pairing (high‐high versus high‐low versus low‐low attainment) impacts English as a Foreign Language (EFL) learner engagement during technology‐enhanced cooperative writing tasks. Seventy‐eight Chinese university learners formed 39 dyads (13 pairs per group) via Tencent Meeting.
Ying Liu, Allen Thurston
wiley   +1 more source

人脐血T/NK 细胞KIR 分子表达的初步探讨

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2002
【目的】探讨脐血中T 淋巴细胞和自然杀伤(NK)细胞上杀伤性抑制性受体(KIR)的表达特性。【方法】采用流 式细胞仪检测26 份正常分娩新生儿脐血的T/ NK 细胞表面KIR 分子表达(CD158a , CD158b 和CD94), 并与正常外周血比较。 【结果】脐血中T 淋巴细胞和NK 细胞均存在KIR 分子表达;脐血和外周血中T 淋巴细胞CD158 分子表达低于NK 细胞(P
陈 纯, 黄绍良, 魏 菁
doaj  

Cloning and Stress Response of the Cold-Regulated Genes of Adenine Nucleotide Translocase 2, the Chaperonin Containing Tailless Complex Polypeptide α and Stearoyl-CoA Desaturase in the Mud Crab, Scylla paramamosain [PDF]

open access: yes, 2015
腺苷酸转移酶(adeninenucleotidetranslocase,ANT),属于线粒体转运蛋白超家族,是线粒体中最丰富的蛋白质之一,主要作用是介导ADP/ATP在细胞质和线粒体基质之间的运输。伴侣素包含T型复合体(thechaperonincontainingtaillesscomplexpolypeptideα,CCTα)是几乎存在所有生物体中的一类分子伴侣,负责细胞内蛋白的组装和折叠。内质网内的硬脂酰去饱和酶(stearoyl-CoAdesaturase,SCD),是一类含铁离子的限速酶 ...
于坤
core  

Learner‐Focused Strategy Instruction From the Teachers’ and the Learners’ Perspective

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Numerous large‐scale quantitative studies have been conducted to yield a macro‐level picture of the effectiveness of strategy instruction. However, little is understood about learners' actual processing of strategy instruction and interaction with the teachers delivering it.
Isobel Kai‐Hui Wang, Andrew D. Cohen
wiley   +1 more source

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