Results 81 to 90 of about 209,042 (243)
Zhongguo shiyan zhenduanxue, 2008 目的探讨乳腺癌ER、PR、Her-2表达与临床病理特征的相关性。方法采用回顾性分析,统计383例乳腺癌患者ER、PR、Her-2的表达;分析ER、PR、Her-2表达的相关性;及其与乳腺癌临床病理特征的关系。结果①ER、PR、Her-2阳性率分别为60.4%、64.1%、17.2%。②ER与PR表达呈正相关;ER、PR分别与Her-2表达负相关;Her-2与ER、PR共同表达呈负相关 ...
郭欢续, 白欧
doaj
Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]
, 2011 Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG +7 more
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Rare Metals, EarlyView.ABSTRACT The growing concern over human health issues, driven by increasingly severe electromagnetic pollution from 5G communication, has made the urgent development of high‐performance electromagnetic wave (EMW) absorbing materials. Although carbide‐based materials are promising because of their conductive and polarization losses, existing single ...
Chenqiang Duan +9 more
wiley +1 more source
FoxO regulates epithelial-mesenchymal transition reprogramming in non-small lung cancer cell through epigenetic modification [PDF]
, 2015 FoxO是Forkhead转录因子O亚家族成员，它能通过调控一系列下游靶基因的表达参与调控细胞周期停滞、细胞凋亡、新陈代谢和抗氧化应激等多个生物学过程，研究表明FoxO作为一个肿瘤抑制因子参与调控肿瘤形成和转移过程。上皮细胞-间质细胞转变(EMT)作为肿瘤形成和转移过程中的关键环节，最近的研究发现FoxO能参与调控EMT过程，然而具体的机制还未得到全面的阐述。本论文以人非小细胞肺癌细胞株A549为研究体系，探索FoxO与EMT之间的关系，实验结果表明在A549细胞中敲低FoxO能诱导EMT的发生 ...
查俊敏
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Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Organic phosphorus mineralization is a critical process in the phosphorus cycle, governing phosphorus bioavailability for plants. The PhoD gene, which encodes the key enzyme alkaline phosphatase, serves as a valuable biomarker for this process.
Sandhya Mishra +3 more
wiley +1 more source
The study of AKAP95 and Cx43 protein co-regulating cell G1/S phase transition [PDF]
, 2016 本研究分为两部分，第一部分采用免疫组织化学实验，包括肺癌组织中AKAP95和CyclinD3、Akt蛋白表达与临床病理学指标的关系及3种蛋白之间的关联性分析、直肠癌组织中AKAP95、CyclinD1、CyclinE1和Cx43蛋白的关联性分析。通过检测51例肺癌组织和15例癌旁组织中细胞周期蛋白D3(CyclinD3)、蛋白激酶A锚定蛋白95(AKAP95)和丝/苏氨酸激酶(serine/threoninekinase，Akt，亦称蛋白激酶B，PKB)的表达发现，AKAP95 ...
原阳阳
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Methods in Ecology and Evolution, EarlyView.Abstract DNA barcode‐based species identification has become pivotal in biodiversity research. Current barcoding‐based deep learning methods have advantages in species identification but exhibit significant limitations. By using COI barcoding alone, previous studies were unable to fully capture species identification features. Prior methods showed that
Bin Ye +4 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2004 目的 探讨HLA I、β2 m、B7 1分子在肿瘤发生、发展中的作用。方法 流式细胞技术检测胃肿瘤细胞和外周血淋巴细胞HLA I、β2 m、B7 1分子的表达 ;放射免疫技术 （RIA）检测血清中 β2 m的含量。结果 ①胃癌细胞表面HLA I分子表达明显降低。②胃癌细胞表面B7 1分子表达明显降低或缺如。③β2 m在肿瘤细胞上的表达明显增高 ;作相关分析发现 ,β2 m与HLA I的表达呈负相关关系 （r=- 0 4 70 ,P
武焕玲 +4 more
doaj
The Role of Messenger RNA Alternative Polyadenylation During Developmental Gene Expression Regulation and Adapdation of Rice [PDF]
, 2016 水稻（Oryzasativa）不仅是世界上最重要的粮食作物之一，也是单子叶模式植物。水稻品种japonicaNipponbare和indica93-11为两个水稻亚种代表，广泛的种植于我国的南北区域，对环境与气候形成一定的适应性，在我国形成北粳南籼的生产格局。它们各自具有独自的生理特性和生长周期。转录组为特定生理条件下，细胞中全部转录产物的集合。通过对水稻发育过程转录组的研究，可以全面地了解基因表达调控在水稻发育过程中的调节作用以及对环境适应性。多聚腺苷化是基因在转录形成成熟的转录本之前的加工过程之一 ...
付海辉
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Lessons learned from screening potential other effective area‐based conservation measures
Conservation Biology, EarlyView.Abstract Other effective area‐based conservation measures (OECMs) are sites that deliver effective biodiversity outcomes irrespective of their management objectives. These areas are widely expected to play an important role in efforts to protect 30% of Earth by 2030.
Carly N. Cook +15 more
wiley +1 more source