Results 31 to 40 of about 5,253 (181)

Clinical and genetic characteristics of adult cerebral adrenoleukodystrophy [PDF]

open access: yes, 2023
Objective·To summarize and analyze the clinical and genetic characteristics of adult cerebral adrenoleukodystrophy(ACALD ).Methods·The data of eight patients with ACALD who attended the Shanghai Sixth People′s Hospital, Shanghai Jiao Tong University ...
CAO Li   +7 more
core   +1 more source

多模态磁共振成像在血管性认知障碍诊断中的研究进展 Advances of Multimodality Magnetic Resonance Imaging in the Diagnosis of Vascular Cognitive Impairment

open access: yesZhongguo cuzhong zazhi, 2018
血管性认知障碍(vascular cognitive impairment,VCI)包括从轻度认知功能受损到痴呆的 各种程度的认知功能受损,伴随着脑结构和脑功能的变化。磁共振成像(magnetic resonance imaging, MRI)作为一种广泛应用的诊断工具,可以无创地观察患者脑组织的变化。结合自动分割算法,对采集 到的MRI数据进行分类,在识别血管性认知障碍方面具有广泛的应用前景。本文对近年来MRI在诊断 血管性认知障碍方面的研究进展和新技术进行综述。 Abstract ...
战扬,崔文韬,韩璎
doaj   +1 more source

血管性认知障碍患者的睡眠紊乱与非药物治疗 Sleep Disorder and Non-drug Therapy in Patients with Vascular Cognitive Impairment

open access: yesZhongguo cuzhong zazhi, 2023
血管性认知障碍患者往往伴有睡眠障碍,睡眠的紊乱进一步降低了患者的生活质量,增加了其脑血管事件的风险,也加重了照料者的负担。有效治疗患者的睡眠障碍不仅可以改善其生活质量,对患者的认知及功能康复也有积极影响。本文对血管性认知障碍患者常见的睡眠紊乱进行综述,着重阐述了睡眠障碍非药物治疗方面的研究成果,并对这些治疗方法未来的研究方向以及在血管性认知障碍患者中的应用前景进行了探讨。 Abstract: Patients of vascular cognitive impairment often ...
张心怡, 陈楚歆, 董建宇, 张宁, 王春雪
doaj   +1 more source

The Relationship between Mild Cognitive Impairment (MCI) and Traditional Chinese Medicine Constitution(TCMC); and intervention methods of traditional Chinese medicine ―Literature Review― [PDF]

open access: yes, 2023
departmental bulletin ...
00127135   +11 more
core  

Changes of serum uric acid, bilirubin and homocysteine levels in patients with early Parkinson’s disease [PDF]

open access: yes
目的 观察早期帕金森病并伴有轻度认知功能障碍(PD-MCI)患者血清间接胆红素(IBIL)、尿酸(UA)、同型半胱氨酸(Hcy)及尿酸/同型半胱氨酸比值(UA/Hcy)的变化,探讨其与PD-MCI的关系。 方法  收集158例早期未经药物治疗的帕金森病(PD)患者的人口学及临床资料,应用Hoehn & Yahr分级评估PD严重程度,MDS-UPDRS III评估运动障碍,蒙特利尔认知评估量表(MoCA)评估全面认知功能状态。102例年龄匹配的健康体检者作为对照组。检测各组血清IBIL ...
Li, Zhen-guang   +2 more
core   +2 more sources

Mediating Role of Family Function between Disability Severity and Family Resilience in Home-living Older Adults with Disability in Minority Areas of Xinjiang [PDF]

open access: yes, 2022
BackgroundAs a multi-ethnic and economically underdeveloped region, Xinjiang faces severe challenges coming with an aging population. To promote active aging under the circumstances of unsatisfied comprehensive strength and imperfect home care system, it
ZHANG Mengmeng, WANG Yuhuan, TANG Xueting, ZHAO Shuhua, ZHOU Jia
core   +1 more source

Risk Factors of Caregiver Burden in Patients With Cognitive Dysfunction: A Scoping Review

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
This scoping review identifies neuropsychiatric symptoms and behaviors as the core risk factor for caregiver burden in cognitive dysfunction, with functional dependence and female caregivers as key drivers. Findings underscore the need for targeted, multi‐domain interventions to alleviate burden across diverse caregiving contexts.
Liu Jinheng   +5 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

体智锻炼在全麻史与轻度认知功能障碍关联中的作用 [PDF]

open access: yes
目的探讨老年人全麻史与轻度认知障碍(MCI)患病的关联性,并分析体智锻炼对这一关联性的影响,为早期预防和及时干预MCI提供新思路。方法基于湖北老年记忆队列的基线调查(2018-2023年),老年人完成整套神经心理评估及体格检查,自我报告全麻和手术史;使用logistic回归模型分析老年人全麻与MCI的关联性,此外,分别进行了麻醉史、麻醉次数与体智锻炼的分层及交互作用分析。结果本研究共纳入5 069名65岁及以上老年人,其中农村1 377人(27.1%),女性2 584名(51%),有全麻者1 427人 ...
张秋茹   +4 more
core   +7 more sources

oleoylethanolamide improves spatial cognitive deficits through enhancing hippocampal neurogenesis after cerebral ischemia [PDF]

open access: yes, 2015
我们先前的研究表明油酰乙醇胺(OEA)对急性脑缺血损伤具有神经保护作用。本研究的目的是探讨OEA对脑缺血引起的空间认知障碍,海马长时程增强作用(LTP)的抑制作用和海马神经发生的影响。结果表明:OEA30mg/kg显著改善大鼠脑缺血后空间认知功能障碍,促进海马长时程增强。另外,我们证实OEA通过促进海马神经发生改善脑缺血后的认知障碍。进一步的研究表明,OEA明显增加海马组织脑源性神经营养因子(BDNF)和过氧化物酶体增殖活化受体(PPARα)的表达 ...
杨立朝
core  

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