Results 41 to 50 of about 5,409 (163)

Random Forest Algrithom for Computer-Aided Alzheimer's Disease Diagnosis [PDF]

open access: yes, 2016
阿尔茨海默症(AD)是世界上最常见的疾病之一。它是一种神经退行性疾病,会使得患者的认知功能出现障碍,记忆力衰退。至目前为止,对其尚未有有效地知了手段。也因此,AD的早期诊断是一个非常重要的研究领域,它吸引了许多研究人员参与到其中来寻找新的有效的诊断方法。 在本文中,我们主要通过随机森林算法,使用被试的MRI图像数据,对其是否可能患有AD病的进行诊断。随机森林算法能够从MRI的高维数据中学习到其低维特征和低维表达,我们使用随机森林算法对AD和正常对照组(NC),AD和轻度认知障碍患者(MCI ...
GAKIZA CANISIUS
core  

Risk Factors of Caregiver Burden in Patients With Cognitive Dysfunction: A Scoping Review

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
This scoping review identifies neuropsychiatric symptoms and behaviors as the core risk factor for caregiver burden in cognitive dysfunction, with functional dependence and female caregivers as key drivers. Findings underscore the need for targeted, multi‐domain interventions to alleviate burden across diverse caregiving contexts.
Liu Jinheng   +5 more
wiley   +1 more source

脑梗死患者认知功能障碍的临床特征与影响因素研究

open access: yesZhongguo shiyan zhenduanxue, 2020
脑梗死是卒中最为常见的一种类型,约占到所有卒中患者的80%,随着医疗技术的提高,病死率显著降低,但脑梗死后很多患者存在日常生活能力障碍,严重影响了患者的生活质量[1]。有研究显示脑梗死后认知功能障碍是影响日常生活能力的主要因素,而脑梗死后认知障碍的表现从轻度障碍到痴呆[2]。脑梗死引起的认知障碍除了血管性因素外,
杨宇, 蒙钟文, 张煜
doaj  

Relationship of Cognitive Function with Emotion and Sleep Architecture in Patients with OSAHS [PDF]

open access: yes, 2022
Background Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a sleep-related breathing disease,which influences patients' sleep quality and emotion regulation due to long-term intermittent hypoxemia and sleep fragmentation.
LIU Yishu, TAN Huiwen, ZENG Yin, XIAO Li
core   +1 more source

Barriers to public engagement with biodiversity conservation

open access: yesConservation Biology, Volume 39, Issue 4, August 2025.
Abstract Addressing biodiversity loss requires public engagement and action, including changes to individual consumption habits, support for on‐the‐ground conservation actions, and advocacy for government action and policy change. Conservation organizations are increasingly focused on encouraging probiodiversity attitudes and behaviors through ...
Emily A. Gregg   +7 more
wiley   +1 more source

多模态磁共振成像在血管性认知障碍诊断中的研究进展 Advances of Multimodality Magnetic Resonance Imaging in the Diagnosis of Vascular Cognitive Impairment

open access: yesZhongguo cuzhong zazhi, 2018
血管性认知障碍(vascular cognitive impairment,VCI)包括从轻度认知功能受损到痴呆的 各种程度的认知功能受损,伴随着脑结构和脑功能的变化。磁共振成像(magnetic resonance imaging, MRI)作为一种广泛应用的诊断工具,可以无创地观察患者脑组织的变化。结合自动分割算法,对采集 到的MRI数据进行分类,在识别血管性认知障碍方面具有广泛的应用前景。本文对近年来MRI在诊断 血管性认知障碍方面的研究进展和新技术进行综述。 Abstract ...
战扬,崔文韬,韩璎
doaj   +1 more source

Early parent‐child interaction and home environments of children exposed prenatally to opioids: A comparison of biological mothers and out‐of‐home caregivers

open access: yesInfant Mental Health Journal: Infancy and Early Childhood, Volume 46, Issue 3, Page 343-358, May 2025.
Abstract Children born to mothers with opioid use disorder (OUD) are at increased risk of maltreatment and out‐of‐home care (OOHC) placement. This study examines the parent‐child interaction quality and home environments of 92 New Zealand children with prenatal opioid exposure (OE) and 106 non‐opioid‐exposed (NE) children.
Samantha J. Lee   +2 more
wiley   +1 more source

脑白质病变与认知障碍关系研究进展

open access: yesZhongguo shiyan zhenduanxue, 2019
WML(脑白质病变)是常见的脑部损害,是小血管疾病的标志,随年龄增长,发病率增加,可以无明显临床症状[1]。研究表明WML引起认知障碍,促进轻度认知障碍的进一步恶化[2]。目前中国是世界上老龄化最严重的国家,与老龄化相伴的认知障碍疾病如AD、血管性痴呆等,已成为老年人认知衰退的主要原因 ...
张亚苹, 何金婷, 徐忠信
doaj  

Effects of ApoE Isoforms Expression on Brain ApoE Lipidation and Amyloid-β Accumulation [PDF]

open access: yes, 2015
在编码人三种不同apoE蛋白亚型(E2、E3和E4)的APOE等位基因(ε2、ε3和ε4)中,APOEε4等位基因是阿尔茨海默病(Alzheimer’sdisease,AD)最重要的遗传风险因子,APOEε2等位基因则具有保护作用。鉴于apoE蛋白亚型对基于调节apoE蛋白表达的AD治疗可能会有不同的影响,我们通过在人APOE基因定位替换(Targetedreplacement,TR)小鼠脑中过表达不同的人apoE亚型,研究脑中表达不同apoE亚型对apoE脂化和β-淀粉样蛋白(Amyloid-β,Aβ)
胡进
core  

Social science integration at state and federal fish and wildlife organizations in the United States

open access: yesConservation Biology, Volume 39, Issue 2, April 2025.
Abstract Increasingly, conservation professionals and scholars recognize the need for more holistic integration of social science in fish and wildlife management. This call is often framed around the complexity of 21st century conservation challenges and changing societal values toward fish and wildlife and its management.
Michael R. Quartuch   +7 more
wiley   +1 more source

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