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NPTX1在胸腺瘤患者中的表达及诊断价值 [PDF]

open access: yesZhongguo Fei Ai Za Zhi, 2021
背景与目的 胸腺瘤是原发于前纵隔最常见的恶性肿瘤,但对于胸腺瘤的诊断没有特异性的实验室指标。本研究旨在通过mRNA微阵列分析技术筛选出对胸腺瘤诊断有提示作用的肿瘤标志物,并加以证实。 方法 前期对31份胸腺瘤和瘤旁胸腺组织进行mRNA微阵列分析,发现胸腺瘤中神经细胞正五聚体1(neuronal pentraxin 1, NPTX1)基因转录水平上调超过4倍。为进一步验证上述结果,采用实时荧光定量聚合酶链反应(polymerase chain reaction, PCR)法、免疫组化法和酶联免疫吸附测定法(
Xin Du   +4 more
semanticscholar   +2 more sources

尿醛固酮浓度在原发性醛固酮增多症中的筛查价值及质谱法和化学发光法检测的比较 [PDF]

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2020
目的了解尿醛固酮浓度(UAC)对于原发性醛固酮增多症(原醛)的诊断价值;对比研究液相色谱串联质谱法(LC-MS/MS)和化学发光法(CLIA)检测UAC结果的一致性并建立各自的诊断切点。方法纳入2018年10月至2019年8月就诊的高血压查因患者133例,其中原醛患者55例(醛固酮瘤30例,特发性醛固酮增生25例),原发性高血压(EH)患者78例。采用CLIA法及LC-MS/MS法平行检测UAC并比较两种方法的相关性、一致性。构建UAC、尿醛固酮/肾素活性比值(UARR)诊断原醛的受试者工作特征(ROC)
樊静   +7 more
doaj   +2 more sources

一种新联合指标对新生儿体重增重趋势的诊断价值

open access: yes亚洲临床医学杂志, 2021
目的:通过筛选多个孕检指标建立一种新联合指标,并分析包括新联合指标在内的多个指标对新生儿体重增重趋势的诊断价值。方法:选取2018年1月-12月入院的86名孕妇按照其分娩的新生儿出生体重水平,分为新生儿出生体重大于平均体重组(n=43)、及新生儿出生体重小于或等于平均体重水平组(n=43)。比较两组在孕期增重、孕前BMI、宫高、腹围等十六个指标差异;利用ROC曲线下面积分析每个指标的诊断价值并与联合诊断指标的诊断能力比较。结果:①宫高、孕周、孕期增重、腹围在两组间比较差异有统计学意义(P<0.05 ...
涛 姚, 景鹤 白, 军 邢, 静思 陈
semanticscholar   +1 more source

Sustainability of medicinal animal products: Tokay geckos and pangolin scales as traditional Chinese medicine 药用动物制品的可持续性:作为传统中药的大壁虎和穿山甲片

open access: yesIntegrative Conservation, Volume 2, Issue 4, Page 176-186, December 2023., 2023
Public opinion toward pangolin and tokay gecko medicinal trade reveals significant differences in attitude and knowledge aspects but not in the percentage of hypothetical users. It is thus interesting to investigate hypothetical user profiles and the driving factors behind their choices. Setting up legal protection status for species is found to be the
Yifu Wang   +7 more
wiley   +1 more source

Diagnostic value of fractional exhaled nitric oxide in predicting cough variant asthma in children with chronic cough: a systematic review and meta-analysis [PDF]

open access: yes, 2023
Objective·To evaluate the values of fractional exhaled nitric oxide (FeNO) for the diagnosis of cough variant asthma (CVA) in children with chronic cough by systematic review and meta-analysis.Methods·PubMed, Embase, Cochrane Library, Web of Science ...
DANG Xiangyang   +3 more
core   +1 more source

Effect and mechanism of microRNAs on various diabetic wound local cells microRNA对各种糖尿病创面局部细胞的作用及机制

open access: yesJournal of Diabetes, Volume 15, Issue 11, Page 955-967, November 2023., 2023
Highlights For the first time, we have examined the impact of microRNA on diabetic wounds at a cellular level. We have analyzed how a particular microRNA influences different types of cells, uncovering its function and mechanism. This study furthers the discovery of the clinical potential of diverse microRNAs by evaluating their distinct effects and ...
Hongjie Li, Shengyu Jing, Hongbo Xu
wiley   +1 more source

Body‐and movement‐oriented interventions for posttraumatic stress disorder: An updated systematic review and meta‐analysis

open access: yesJournal of Traumatic Stress, Volume 36, Issue 5, Page 835-848, October 2023., 2023
Abstract This study is an update of the meta‐analysis we published in 2019 on the effectiveness of body‐ and movement‐oriented interventions (BMOIs) for adults with posttraumatic stress disorder (PTSD) in decreasing PTSD symptoms and secondary outcomes of depressive symptoms, sleep disturbance, and interoceptive awareness.
Minke M. van de Kamp   +6 more
wiley   +1 more source

Ultrasound-based Thyroid Nodule Malignancy Risk Stratification in Differentiating Benign and Malignant Thyroid Nodules:a Comparative Analysis between the C-TIRADS and ATA Guidelines [PDF]

open access: yes, 2022
BackgroundThe 2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS (C-TIRADS for short) put forward a method for stratifying the malignancy risk of thyroid nodules, but there are few studies about its ...
LI Jian, YIN Yanhua, QI Jianguo, WANG Zhou, REN Yongfeng, WANG Shanshan, ZHANG Weili, WANG Xiaojun, TANG Kun
core   +1 more source

Psychological impact of simple scoring system for predicting early pregnancy outcome in pregnancy of uncertain viability: randomized controlled trial

open access: yesUltrasound in Obstetrics &Gynecology, Volume 61, Issue 5, Page 624-631, May 2023., 2023
ABSTRACT Objective To investigate whether psychological wellbeing of women with an intrauterine pregnancy of uncertain viability can be modified during the waiting period to final diagnosis, by offering predictive information regarding the likely outcome of the pregnancy (chance of ongoing viability). Methods This was a single‐center two‐arm randomized
K. Lawson, T. Bourne, C. Bottomley
wiley   +1 more source

Value of Kyoto gastritis score and modified prediction model in diagnosing Helicobacter pylori infection status under gastroscopy in Chinese population [PDF]

open access: yes, 2023
Objective: To validate the application value of Kyoto gastritis score in diagnosing Helicobacter pylori (Hp) infection status under gastroscopy in Chinses population, and to construct a modified prediction model to improve the diagnostic value of Hp ...
QIAN Danye, MENG Xiangjun, ZHU Liming
core   +1 more source

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