Results 1 to 10 of about 8,403 (128)

Pay attention to standardized diagnosis and treatment of corticosteroid-responsive cough [PDF]

open access: yes, 2023
The global prevalence of chronic cough in adults is 9.6%.In 2008, the cough special issue of Lancet published a diagnosis and treatment plan to distinguish the causes of chronic cough based on eosinophilic airway inflammation or sensitivity to ...
SHI Cuiqin, YU Li
core   +1 more source

Research Progress in Food Allergen Labeling Management and Its Enlightenment to China [PDF]

open access: yes, 2023
In recent years, the incidence of food allergy has continued to rise globally. Food allergy has become a global food safety and public health problem.
XIONG Wenwen, ZENG Binghui, WANG Junjuan, HAO Mengzhen, CHE Huilian
core   +1 more source

Effect and mechanism of microRNAs on various diabetic wound local cells microRNA对各种糖尿病创面局部细胞的作用及机制

open access: yesJournal of Diabetes, Volume 15, Issue 11, Page 955-967, November 2023., 2023
Highlights For the first time, we have examined the impact of microRNA on diabetic wounds at a cellular level. We have analyzed how a particular microRNA influences different types of cells, uncovering its function and mechanism. This study furthers the discovery of the clinical potential of diverse microRNAs by evaluating their distinct effects and ...
Hongjie Li, Shengyu Jing, Hongbo Xu
wiley   +1 more source

Body‐and movement‐oriented interventions for posttraumatic stress disorder: An updated systematic review and meta‐analysis

open access: yesJournal of Traumatic Stress, Volume 36, Issue 5, Page 835-848, October 2023., 2023
Abstract This study is an update of the meta‐analysis we published in 2019 on the effectiveness of body‐ and movement‐oriented interventions (BMOIs) for adults with posttraumatic stress disorder (PTSD) in decreasing PTSD symptoms and secondary outcomes of depressive symptoms, sleep disturbance, and interoceptive awareness.
Minke M. van de Kamp   +6 more
wiley   +1 more source

Effective treatment of canine chronic cutaneous lupus erythematosus variants with oclacitinib: Seven cases

open access: yesVeterinary Dermatology, Volume 34, Issue 1, Page 53-58, February 2023., 2023
Background – The treatment of canine chronic cutaneous lupus erythematosus (CCLE) variants generally requires immunosuppression, which often results in potentially severe adverse effects. Janus kinase inhibitors, like oclacitinib, might be a valuable treatment option due to their rapid inhibition of the action of interferons known to be relevant in the
Richard G. Harvey   +3 more
wiley   +1 more source

A masked, randomised clinical trial evaluating the efficacy and safety of lokivetmab compared to saline control in client‐owned dogs with allergic dermatitis

open access: yesVeterinary Dermatology, Volume 32, Issue 5, Page 477-e131, October 2021., 2021
Background – Interleukin (IL)‐31 is an important mediator in canine atopic dermatitis (cAD) and also may be dysregulated in other allergic diseases. Hypothesis/Objectives – To demonstrate the efficacy and safety of lokivetmab (canine anti‐IL‐31 monoclonal antibody) for treatment of pruritus associated with allergic dermatitis in dogs.
Leen Van Brussel   +4 more
wiley   +1 more source

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Chinese (Mandarin) translation

open access: yesDevelopmental Medicine &Child Neurology, Volume 61, Issue 3, Page E1-E35, March 2019., 2019
目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua   +6 more
wiley   +1 more source

超声心动图在ICU冠心病患者介入治疗前后的监测价值分析

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨超声心动图在ICU冠心病患者介入治疗前后的监测价值。方法以本院2017年9月至2018年7月收治、并进行择期PCI治疗的71例冠心病患者为研究组,同期入院体检的70例健康志愿者为对照组,对比两组的超声心动图特征,分析超声心动图参数对冠心病的诊断价值;同时,对比分析研究组治疗前和治疗后3个月的超声心动图特征,分析超声心动图参数对冠心病患者预后的预测价值。结果研究组LVESVI和LVEDVI高于对照组,CI和LVEF低于对照组,差异有统计学意义 ...
刘丽, 张芳, 常琳
doaj  

血清TSGF及DKK-1水平对结直肠癌的诊断价值及与临床病理特征的关系

open access: yesZhongguo shiyan zhenduanxue, 2021
尽管结直肠的筛查、诊断方式不断更新,治疗方式不断改进,但由于结直肠癌早期症状不明显,有些患者一经诊断已进展到中晚期,导致5年生存率不高[1]。目前,结直肠癌的诊断指标为癌胚抗原(CEA)及糖类抗原19-9(CA19-9)等,但其易受多种疾病因素的干扰,导致漏诊时有发生,延误治疗时机[2]。肿瘤特异性生长因子(TSGF)为肿瘤细胞生长、增殖时分泌的一类物质,对肿瘤的诊断有一定价值[3]。分泌型糖蛋白(DKK-1)为Wnt/β-catenin信号通路的抑制蛋白,可抑制肿瘤细胞的增殖、生长和迁移[4 ...
董典博, 董晓燕, 俞海龙
doaj  

Performance of QUiPP App v.2 tool for prediction of preterm birth in asymptomatic high‐risk women attending preterm specialist clinic: external validation study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 64, Issue 1, Page 71-78, July 2024.
ABSTRACT Objective To validate externally the QUiPP App v.2 algorithms in an independent cohort of high‐risk asymptomatic women attending a preterm birth (PTB) surveillance clinic in Ireland. Methods This was a retrospective, single‐center, observational study assessing discrimination and calibration of the QUiPP App v.2 at six predetermined clinical ...
L. Creswell   +4 more
wiley   +1 more source

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