Results 11 to 20 of about 45,331 (170)

Digital Rights Activism in Multilevel Governance

open access: yesEuropean Policy Analysis, EarlyView.
ABSTRACT Multilevel governance (MLG) without a clear hierarchical structure can create power imbalances among various actors, particularly in settings with overlapping jurisdictions and policy areas. This dynamic is especially pronounced in Internet governance, which faces a complex interplay of domestic laws, state interdependence, and heightened ...
Alison Harcourt
wiley   +1 more source

Conservation Funding at the Local Level 地方层面的保护资金

open access: yesWildlife Letters, EarlyView.
Direct conservation fund transfer to local communities ensures the involvement of these communities in decision‐making and fund utilisation, which will ultimately lead to effective biodiversity conservation. A Cakchiquel family in the hamlet of Patzutzun, Guatemala, 1993. Credits: John Issac. Source: UNEP‐WCMC Internal Resources.
Jithu K Jose
wiley   +1 more source

Jellyfish blooms restructure plankton dynamics and trophic linkages in coastal waters

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Jellyfish blooms are increasing globally in frequency and intensity, introducing complex ecological interactions, yet the mechanisms by which they alter ecosystem structure remain poorly characterized due to a lack of sustained field observations.
Pengpeng Wang   +4 more
wiley   +1 more source

Evaluating synthetic substitutes to reduce illegal harvesting and support species recovery

open access: yesConservation Biology, EarlyView.
Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened species. Yet, there is little evidence on whether product substitution prevents illegal or unsustainable harvesting and contributes to the recovery of threatened populations.
Aditya Shekhar Malgaonkar   +17 more
wiley   +1 more source

Basic income trials and the politics of scale: A research agenda

open access: yesPolicy Studies Journal, EarlyView.
Abstract The growing popularity of basic income has led to extensive trials of the policy in numerous settings across the world. However, analysis of the politics of basic income, and in particular the political dynamics preceding and resulting from trial programs, lags. In response, we propose a research agenda that uses political scale to investigate
Jurgen De Wispelaere   +2 more
wiley   +1 more source

转移力不同的肺癌克隆细胞中nm23-H1基因产物NDPK 的表达

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2000
【目的】比较转移抑制基因nm23-H1 表达产物核苷酸二磷酸激酶(nucleoside diphosphate kinase , NDPK)在转移力 不同的肺癌克隆株中的表达。【方法】通过单细胞克隆技术及裸鼠接种筛选出高转移及低转移的人肺巨细胞癌克隆细胞株及 高转移的人肺腺癌克隆细胞株, 用LSAB 免疫组化法检测nm23-H1 基因产物NDPK 的表达。【结果】NDPK 在高转移及低转 移的人肺巨细胞癌克隆细胞移植瘤及转移瘤中均有表达, 高转移株的阳性细胞数目及强度均高于低转移株和裸鼠正常肺组
张 彬   +3 more
doaj  

Functions of Periostin in pre-metastatic immunosuppressive niches of breast tumor metastasis [PDF]

open access: yes, 2016
在肿瘤发生发展过程中,肿瘤细胞及其相关间质细胞向肿瘤微环境中分泌大量促癌细胞因子以及趋化因子,促使骨髓来源的免疫抑制细胞(myeloid-derivedsuppressorcells,MDSCs)向远处靶器官浸润,形成免疫抑制微环境,为肿瘤细胞的转移提供有利条件,从而促进肿瘤细胞的转移。在乳腺癌肿瘤组织中,细胞外基质蛋白Periostin主要由肿瘤相关成纤维细胞分泌,并参与调控肿瘤的发生发展过程。然而,关于Periostin蛋白在MDSCs介导的转移前微环境形成中的功能尚不清楚 ...
熊珊珊
core  

Powerful representation of the poor? German welfare associations' narrative advocacy during COVID‐19

open access: yesPolicy Studies Journal, EarlyView.
Abstract The COVID‐19 pandemic sparked unprecedented experimentation in the German social assistance system, leading to changes previously considered impracticable by policymakers. This included a sanctions moratorium, easier access to benefits, and temporary cash transfers, all of which were advocated by welfare associations—key organized interests ...
Christopher Smith Ochoa
wiley   +1 more source

尿氨基末端肽在转移性骨肿瘤诊断中的意义

open access: yesZhongguo shiyan zhenduanxue, 2009
目的探讨溶骨性骨代谢生化指标尿Ⅰ型胶原交联氨基末端肽(uNTX)检测在恶性肿瘤骨转移诊断中的价值。方法对24例骨转移患者及34例无骨转移的患者,利用ELISA方法测定uNTX水平。结果骨转移组患者uN-TX明显高于无骨转移组 ...
王玲, 王宏, 邱阳
doaj  

Role of RNA helicase DHX32 in the metastasis of hepatocellular carcinoma [PDF]

open access: yes, 2016
肝细胞癌是全球性的高致死率肿瘤之一,血管侵犯和转移是肝细胞癌患者术后易复发及5年生存率较低的重要原因,有效的抗转移策略无疑能给患者带来福音。因此,越来越多的研究致力于探讨肝细胞癌发生侵袭转移的分子机制,并希望通过找到某些关键分子来干预肿瘤的转移。 DHX32是人类RNA螺旋酶的家族成员之一,最早被发现是在急性淋巴细胞白血病中低表达并参与淋巴细胞的分化,但是它的生物学功能尚未明确。我们课题组前期通过差异基因显示技术发现DHX32在结直肠癌中表达上调,功能研究结果显示DHX32与结直肠癌细胞的增殖 ...
胡情
core  

Home - About - Disclaimer - Privacy