Results 11 to 20 of about 45,563 (170)
Evaluating synthetic substitutes to reduce illegal harvesting and support species recovery
Abstract Providing synthetic substitutes is a widely promoted strategy to shift consumer demand away from wildlife products derived from threatened species. Yet, there is little evidence on whether product substitution prevents illegal or unsustainable harvesting and contributes to the recovery of threatened populations.
Aditya Shekhar Malgaonkar +17 more
wiley +1 more source
Identification of Candidate Plasma Altered miRNA Associated with Bone Metastasis of Lung Cancer [PDF]
目的:应用高通量miRNA芯片及荧光定量PCR技术筛选及鉴定肺癌骨转移血浆中差异表达的miRNA。 方法:搜集2013至2015年在厦门大学附属第一医院入院的45例肺癌病人外周血标本。选取4例肺癌骨转移与4例肺癌无骨转移病人血浆,应用miRNA芯片技术对差异表达的miRNA进行筛选。应用IPA分析差异miRNA参入的信号通路。应用Real-timePCR检测候选差异表达miRNA,进行验证。 结果:通过比对,成功建立了肺癌骨转移与肺癌无骨转移血浆miRNA芯片表达谱,筛选出了12个差异表达miRNA ...
王文一
core
Basic income trials and the politics of scale: A research agenda
Abstract The growing popularity of basic income has led to extensive trials of the policy in numerous settings across the world. However, analysis of the politics of basic income, and in particular the political dynamics preceding and resulting from trial programs, lags. In response, we propose a research agenda that uses political scale to investigate
Jurgen De Wispelaere +2 more
wiley +1 more source
Functions of Periostin in pre-metastatic immunosuppressive niches of breast tumor metastasis [PDF]
在肿瘤发生发展过程中,肿瘤细胞及其相关间质细胞向肿瘤微环境中分泌大量促癌细胞因子以及趋化因子,促使骨髓来源的免疫抑制细胞(myeloid-derivedsuppressorcells,MDSCs)向远处靶器官浸润,形成免疫抑制微环境,为肿瘤细胞的转移提供有利条件,从而促进肿瘤细胞的转移。在乳腺癌肿瘤组织中,细胞外基质蛋白Periostin主要由肿瘤相关成纤维细胞分泌,并参与调控肿瘤的发生发展过程。然而,关于Periostin蛋白在MDSCs介导的转移前微环境形成中的功能尚不清楚 ...
熊珊珊
core
Powerful representation of the poor? German welfare associations' narrative advocacy during COVID‐19
Abstract The COVID‐19 pandemic sparked unprecedented experimentation in the German social assistance system, leading to changes previously considered impracticable by policymakers. This included a sanctions moratorium, easier access to benefits, and temporary cash transfers, all of which were advocated by welfare associations—key organized interests ...
Christopher Smith Ochoa
wiley +1 more source
转移力不同的肺癌克隆细胞中nm23-H1基因产物NDPK 的表达
【目的】比较转移抑制基因nm23-H1 表达产物核苷酸二磷酸激酶(nucleoside diphosphate kinase , NDPK)在转移力 不同的肺癌克隆株中的表达。【方法】通过单细胞克隆技术及裸鼠接种筛选出高转移及低转移的人肺巨细胞癌克隆细胞株及 高转移的人肺腺癌克隆细胞株, 用LSAB 免疫组化法检测nm23-H1 基因产物NDPK 的表达。【结果】NDPK 在高转移及低转 移的人肺巨细胞癌克隆细胞移植瘤及转移瘤中均有表达, 高转移株的阳性细胞数目及强度均高于低转移株和裸鼠正常肺组
张 彬 +3 more
doaj
Research on Influence of China’s Central Transfer Payments on Local Fiscal Expenditure Competion [PDF]
中央与地方的关系问题一直是中国经济体制改革中的重要内容。特别是1994年进行分税制改革后,明确了中央和地方政府之间的收入分配关系,地方政府逐渐拥有了对财政收入的控制权。地方政府对地方经济利益的和官员政绩的追逐等原因,使地方财政支出竞争不断加剧,在刺激了我国经济增长的同时,其负面效应也逐步凸现。中央对地方的财政转移支付[以下文中简化表述为“中央转移支付”]作为联系中央和地方的最直接政策工具,在调节地方财政收支关系方面起着十分重要的作用。因此,研究中央转移支付对地方财政支出竞争的影响,具有十分重要的现实意义。
王艺珊
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ABSTRACT Why did Australia go from the White Australia Policy, which excluded non‐whites, to institutionalizing multiculturalism policy in the 1970s? This question defies traditional political ideologies of the major political parties, which had long supported the White Australia Policy. This article is a rare empirical demonstration of the Five‐Thread
Julius C. S. Mok
wiley +1 more source
目的探讨溶骨性骨代谢生化指标尿Ⅰ型胶原交联氨基末端肽(uNTX)检测在恶性肿瘤骨转移诊断中的价值。方法对24例骨转移患者及34例无骨转移的患者,利用ELISA方法测定uNTX水平。结果骨转移组患者uN-TX明显高于无骨转移组 ...
王玲, 王宏, 邱阳
doaj
Roles of Netrin-1/Slit3 in the metastasis of fibrosarcoma [PDF]
神经导向因子Netrins及Slits是人们在研究神经系统发育过程中被发现的,在神经轴突穿越中线的过程中,Slit/Robo信号与Netrin/DCC信号之间的协调互作对轴突顺利穿越中线并到达对侧靶点至关重要。在近年的研究中发现,Netrins及Slits家族对肿瘤的生长和转移也具有重要的作用,然而关于Netrin-1与Slit3及其相互作用在纤维肉瘤中的作用还鲜有报道。成纤维肉瘤细胞HT1080是高转移性的恶性成纤维肉瘤细胞,是研究肿瘤侵袭转移的常用模型,本论文对Netrin ...
郑龙庆
core

