[Luspatercept combined with roxadustat in the treatment of refractory myelodysplastic neoplasms with ring sideroblasts: a prospective, randomized, single-center study]. [PDF]
目的 观察罗沙司他联合罗特西普治疗难治性低危骨髓增生异常肿瘤(MDS)伴环状铁粒幼细胞(MDS-RS)的疗效和安全性。 方法 本研究为单中心前瞻性随机对照试验,招募至少经rhEPO治疗后难治的MDS-RS患者,按照1∶2比例随机分配至罗特西普和罗沙司他联合用药组和罗特西普单药组。主要终点为治疗12周红系反应,次要终点包括治疗24周红系反应、治疗12周内脱离输血时间≥8周等。 结果 共入组48例患者,联合用药组(16例)和单药组(32例)在基线人口学特征、实验室指标、IPSS-R危险度、输血负担 ...
Lu XY +5 more
europepmc +2 more sources
研究河流输沙量具有重要的理论和实践意义。近60年在气候变化和人类活动日益增强的背景下,全球众多河流输沙量都发生显著变化。基于全球河流输沙量数据库和区域河流输沙量研究成果,从全球尺度梳理全球河流输沙量现状、输沙量空间分布格局及其影响因素和输沙量变化及其影响因素3方面进行分析研究。结果表明:(1)全球河流年均总输沙量在2×1010 t左右,对全球主要36条河流输沙量数据分析表明大多数河流输沙量显著减少;(2)地质地貌条件是河流输沙量控制性因素,气象水文条件和人类活动对河流间输沙量差异的贡献大致相当;(3 ...
景昭伟, 赵宏飞
doaj +1 more source
Variation Characteristics of Sediment Transport for a Vertical Gauze Sand Barrier During Different Sampling Seasons [PDF]
[Objective] The variation characteristics of sediment transport for different specifications of gauze sand barriers in spring, summer and autumn were obserred continuously in order to provide a scientific basis for further evaluation of the sand-fixing ...
Gao Haiyan +4 more
core +1 more source
Monitoring and Analysis on Ecological Environment in Near-shore Waters of Yellow River Estuary During 2015—2020 [PDF]
[Objective] The water quality of Bohai Sea was monitored from 2015 to 2020, and the correlation between the change of ecological environment in the coastal waters of the Yellow River estuary and sediment and runoff into the sea was analyzed, in order to ...
Li Su, Zhang Xiang
core +1 more source
Dynamic Monitoring of Soil and Water Loss at Wuding River Basin, a Typical Tributary of Middle Reaches of Yellow River [PDF]
[Objective] The distribution and dynamic characteristics of soil and water loss at Wuding River, a typical coarse sediment tributary in the middle reaches of the Yellow River, were analyzed in order to provide a scientific basis for soil and water ...
Zhang Dong, Zhao Hui, Zhao Yuan
core +1 more source
Utilization Potential of Water Resources in Check Dams in Gansu Province [PDF]
[Objective] The potential of check dams to retain silt and utilize water resources were analyzed in order to provide a basis for water resource utilization and management of check dams.
Jin Feng +5 more
core +1 more source
Spatial and Temporal Distribution Characteristics of Water Quality in Beiluo River and Pollution Sources Based on Principal Component Analysis [PDF]
[Objective] The water quality of four monitoring sections of the main stream of the Beiluo River from 2014 to 2020 were evaluated and analyzed in order to provide a basis for further improving the water environment of the river basin.
Li Su, Zhang Xiang
core +1 more source
Characteristics of Sand-driving Wind Regime and Sediment Transport at Northeast Edge of Bayan Wendur Desert [PDF]
[Objective] The characteristics of sand-driving wind and sand-transporting potential are the key indexes for evaluating the regional wind energy environment.
Dang Xiaohong +5 more
core +1 more source
Ecological Protection Effects Provided by Sand Barriers in a Grassland Mining Area [PDF]
[Objective] The wind protection effectiveness of different sand barriers and their effects on surface soil particle size composition, soil nutrients and vegetation growth werer studied in order to provide a theoretical basis for the optimal selection of ...
Cong Longyu +5 more
core +1 more source
Protective Effect of Shelterbelt on Strip Fields in Southwest Margin of Taklimakan Desert [PDF]
[Objectives] The windbreak efficiency of shelterbelts with different permeability on strip fields at the edge of the oasis in the Taklamakan Desert was analyzed in order to provide theoretical guidance for sustainable development of local grid strip ...
Cai Kaixu +3 more
core +1 more source

