Results 51 to 60 of about 1,178 (146)
Clinical prospects and research strategies of long non-coding RNA encoding micropeptides. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2023 Wang X +5 more
europepmc +1 more source
Progress of Microsatellite (GT/CA)n Repeat Polymorphisms in Non-small Cell Lung Cancer [PDF]
Non-small cell lung cancer (NSCLC) is the most important histological type of lung cancer. This disease affects a large number of patients, and the prognosis of advanced patients is poor.
FU Yuting +4 more
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Zhongguo shiyan zhenduanxue, 2021 在病因和发病机制的TOAST分型中,以大动脉粥样硬化型脑梗死最为常见。随着分子生物学技术的发展,越来越多的microRNA被发现参与机体代谢的各个途径,对动脉粥样硬化斑块形成起到重要调节作用。本文针对大动脉粥样硬化型脑梗死发生、发展的关键环节,综述了microRNA在其中的作用和预测价值。1 miRNA概述微小核糖核苷酸(MicroRNAs),简称miRNA,长度18-25个核苷酸[1],为内源性单链非编码RNA。其通过与特定的信使RNA(mRNAs ...
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Roles of long non-coding RNAs in digestive tract cancer and their clinical application. [PDF]
Zhejiang Da Xue Xue Bao Yi Xue Ban, 2023 Zhang Z, Wang X.
europepmc +1 more source
Current status and future prospects of clinical trials for radioiodine-refractory thyroid cancer [PDF]
Radioiodine-refractory thyroid cancer (RAIR-TC) refers to thyroid cancer that is unable to or difficult to benefit from 131I treatment. The type of RAIR-TC we commonly encounter is differentiated thyroid cancer (DTC), which is originally well ...
LI Ruping, YANG Hui
core +1 more source
Long noncoding RNA and atrial fibrillation. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2021 Yu B, Xie C, Yu S, Hu Y.
europepmc +1 more source
Research progress on the pathogenesis of acute lung injury in sepsis [PDF]
Sepsis is a systemic inflammatory response syndrome caused by severe infection leading to host dysfunction，often involving multiple organs and causing functional failure.
WANG Qin，YU Xu，LI Qingying，LU Yibin
core +2 more sources
骨肉瘤细胞外泌体激活肺组织成纤维细胞炎性信号通路 [PDF]
, 2020 目的本研究旨在研究骨肉瘤细胞来源外泌体对靶器官微环境的调控作用及其分子机制。方法提取骨肉瘤细胞143B外泌体并鉴定，通过PKH26荧光染色后经尾静脉注入裸鼠体内，24 h后提取肝、脾、肺、肾及脑组织，荧光显微镜下计数不同视野红色荧光数量；通过免疫荧光检测不同类型细胞中外泌体摄取情况；143B外泌体与人肺成纤维细胞共培养，荧光显微镜检测摄取情况，进一步利用qPCR检测炎性因子IL-1β、IL-6及TNF-α表达水平，通过蛋白印迹法检测炎性信号通路NF-κB通路p-p65和MAPK通路p-ERK及p ...
刘伟海 +7 more
core
Effect of long non-coding RNA 114227 on gastric cancer cell proliferation and migration. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Gan H +5 more
europepmc +1 more source
长链非编码RNA TUG1通过调节miR-145影响宫颈癌发生发展机制研究
Zhongguo shiyan zhenduanxue目的探讨长链非编码RNA TUG1在调控miR-145表达水平的作用，分析其对于宫颈癌发生发展机制的影响。方法选取2020年1月到2023年12月新疆医科大学第一附属医院患者宫颈癌组织及细胞株，通过RT-PCR实验和qRT-PCR实验，检测长链非编码RNA TUG1、miR-145的表达水平，进行siRNA 转染、CCK-8细胞增殖检测、Annexin V-FITC流式细胞术实验以及细胞克隆形成实验，分析si-TUG1 、anti-miR-145对宫颈癌细胞株的增殖、凋亡及放射照射敏感性的影响 ...
迪 丽达尔·斯地克 +2 more
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