Zhongshan Daxue xuebao. Yixue kexue ban糖尿病肾脏疾病（DKD）已成为我国慢性肾脏病（CKD）的首位住院病因，也是终末期肾脏病（ESRD）和新增血液透析的主要原因。DKD具有起病隐匿，知晓率低，病情持续进展，预后差等特点，目前仍缺乏治疗的特效药物及方法。准确评估和识别DKD临床预后不良的高风险患者，及早进行干预，对提高DKD患者生存率和生活质量、改善预后具有重要意义。目前DKD预后评估的方法主要包括病理分型、临床指标、数学模型以及生物标志物，多种方法为DKD预后的早期预测及干预提供了手段，但各有利弊。本文对近年研究进展进行综述 ...
李安岚, 盛梅笑
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实时二维剪切波弹性成像评估慢加急性肝衰竭患者的预后 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2017 【目的】探讨实时二维剪切波弹性成像（2D SWE）评估慢加急性乙型肝炎肝衰竭（ACLF-HBV）患者预后的临床 应用价值。【方法】入组对象为2013年10月1日至2015年12月31日我院感染科确诊的312例慢加急性乙型肝炎肝衰竭患 者。观察终点为90 d，根据临床结局分为好转组192例和恶化组120例。入组后3 d内，应用2D SWE进行肝脏硬度测量， 收集患者血常规、凝血、生化等血清学指标，观察患者肝实质回声均匀度、肝包膜光滑度、右肝厚度、胆囊壁厚度、脾脏指 数、腹水指数、门静脉主干内径 ...
金洁玚 +5 more
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The value of combined detection of LDHA and PD-L1 in predicting the efficacy and prognosis of advanced gastric cancer patients treated with PD-1 inhibitor [PDF]
, 2023 Background and purpose: The response rate of gastric cancer patients to programmed death-1 (PD-1) inhibitor is relatively low. Establishing a useful efficacy prediction method to screen the superior gastric cancer patients receiving anti-PD-1 therapy ...
ZUO Xueliang, CHEN Zhiqiang, DONG Runyu, WANG Zhixiong, CAI Juan
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The Study of the Value of High Mobility Group Protein B1 Combined with Acute Physiological Score in the Diagnosis and Prognosis of Children with Severe Pneumonia [PDF]
, 2022 BackgroundSevere pneumonia in children is a common respiratory critical illness, and accurate assessment of its prognosis is the key to reasonable clinical decision-making. High mobility group protein B1 (HMGB1) and acute physiology score (APS) have high
KANG Ping, LI Yi, TANG Yu
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Clinical implication of PD-L2 in the prognosis assessment of HNSCC immunotherapy [PDF]
, 2023 Background and purpose: Programmed death-1 (PD-1) monoclonal antibody therapy plays an increasingly important role in the treatment of head and neck squamous cell carcinoma (HNSCC).
HUANG He, JU Houyu, YANG Wenyi, YAN Ming, REN Guoxin, HU Jingzhou
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Expression of plasma methylated Septin9 gene and its clinical significance in patients with gastric cancer [PDF]
, 2023 Background and purpose: Gastric cancer is one of the most common malignant tumors in our country. The diagnosis and treatment process of gastric cancer lacks of sensitive and specific biomarker.
CHEN Xinning, JIANG Huiqin, YANG Yihui, YU Qian, ZHANG Chunyan, WANG Beili, PAN Baishen, GUO Wei
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, 2017 中枢神经系统（CNS）由大量的神经细胞组成,星形胶质细胞是其中分布最广的一类神经胶质细胞,具有营养支持、调节神经递质及影响突触功能等多种生理功能。星形胶质细胞高表达基因-1（AEG-1）是一种原癌基因,对多种CNS肿瘤细胞的增殖、发展及转移有重要影响。本文从AEG-1对CNS肿瘤的诊断、治疗和预后评估方面的作用进行综述 ...
叶翔, 吴小艳, 许奇平, 邢惠琴
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Study the correlation of FIB-4 and sST2 levels with heart failure [PDF]
, 2023 Objective To investigate the correlation between hepatic fibrosis index-4 （FIB-4） and soluble growth stimulating gene 2 protein （sST2） with the incidence and severity of heart failure.
Tao Xuejiao, Lu Junkun, Chen Jiahui, Gao Yujin
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Correlation between fragmented QRS and the short-term prognosis of patients with acute myocardial infarction [PDF]
, 2014 This study is aimed to investigate the clinical significance and the short-term prognostic value of fragmented QRS (fQRS) for patients with acute myocardial infarction (AMI).
Chih-Chi Hsu +4 more
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Detection of EGFR and COX-2 Expression by Immunohistochemical Method on a Tissue Microarray Section in Lung Cancer and Biological Significance [PDF]
, 2010 Background and objective Epidermal growth factor receptor (EGFR) and cyclooxygenase-2 (COX-2), which can regulate growth, invasion and metastasis of tumor through relevant signaling pathway, have been detected in a variety of solid tumors.
Congzhong ZHU, Juan LIU, Xinyun WANG
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