Advances in Research on Lactate Metabolism Disorders and Their Effect on Immunotherapy in Lung Adenocarcinoma [PDF]
Recent studies have identified that metabolic reprogramming in lung adenocarcinoma cells, particularly lactate metabolism disorders, plays a crucial role in tumor development and immune therapy response.
Cixiang CHEN +6 more
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Application of pyroptosis score in the treatment and prognosis evaluation of gastric cancer. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban, 2023 Li L, Liao A.
europepmc +1 more source
Zhongguo shiyan zhenduanxue, 2021 目的探讨血栓弹力图对脓毒症诱发凝血病(SIC)的诊断及预后评估作用。方法连续收集2018年12月至2020年9月中国康复研究中心急诊科收治的脓毒症患者150例,根据SIC评分系统将患者分为SIC组(64例)和非SIC(86例)组,根据SIC患者的预后分为存活组(21例)和死亡组(43例),分别比较两组间血栓弹力图R值、K值、α角、MA值及CI值,采用受试者工作特征(ROC)曲线评价血栓弹力图各指标对SIC的诊断及预后评估的临床价值。结果与非SIC组相比,SIC组R值、K值显著延长,α角 ...
李俊玉 +6 more
doaj
Research advances in the association of epithelial cell adhesion molecule with lung cancer, breast cancer, and some digestive system tumors [PDF]
Epithelial cell adhesion molecule (EpCAM) was first identified in colon cancer cells and is involved in the regulation of cell adhesion, proliferation, differentiation, migration, and signal transduction.
CUI Jiali, WANG Qing
core +1 more source
Research on T Lymphocyte Subsets and NK Cells Activity in Peripheral Blood of Hypopharyngeal Squamous Cell Carcinoma [PDF]
, 2017 目的:分析下咽鳞状细胞癌患者外周血T淋巴细胞亚群和NK细胞活性情况,旨在为相关研究工作提供参考资料。方法:择取2011年6月-2016年5月本院收治的95例下咽鳞状细胞癌病患为病例组,另取此期间内来本院接受健康检查的72例志愿者为正常组。使用流式细胞仪对病患开展相关检查,分析病例组与正常组的淋巴细胞亚群、NK活性情况以及不同临床分期的下咽癌病患外周血T淋巴细胞亚群以及NK细胞活性之间的关系。结果:与正常组相比,病例组的NK细胞、总B淋巴细胞、总T淋巴细胞、辅助/抑制T细胞、辅助T细胞偏低(P0.05 ...
刘存山 +7 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2018 目的探讨阳性淋巴结对数比(LODDS)分期对Ⅲ期直肠癌患者术后3年无疾病生存(DFS)的评估价值。方法收集我院2010年1月至2014年12月就诊的Ⅲ期直肠癌根治术后患者的临床病理资料及随访数据,受试者工作特性(ROC)曲线计算LODDS的最佳截点值并分组,单因素和多因素分析患者的预后影响因素,ROC曲线下面积(AUC)比较pN分期、LODDS分期对3年DFS的预后评估能力。结果 LODDS分期最佳截点值为-0.3552,单因素分析结果显示:年龄(P=0.015)、癌结节(P=0.000)、神经侵犯 ...
张颖, 周维国, 赵丽波
doaj
Zhejiang Daxue xuebao. Lixue ban, 2015 通过分析1984~2010年影响浙江省台州市的台风灾害资料，以新构建的台风规范化灾情指数评估台州历史台风的灾情等级，比较符合台州市的实际灾情状况.结果表明：台风规范化灾情指数预报模型拟合率较高，拟合误差1级准确率达到了88.00%以上；新指数模型计算简单，评估效果较好，可为政府及相关部门提供定量化、科学化的灾情评估和灾后灾情评估产品.
YANGWanyu(杨万裕) +3 more
doaj +1 more source
Establishment of a prognostic risk scoring model for patients with pancreatic ductal adenocarcinoma based on cell ferroptosis-related genes and its application value [PDF]
Objective To establish a prognostic risk scoring model for patients with pancreatic ductal adenocarcinoma (PDAC) based on cell ferroptosis-related genes, and to investigate its application value.
QING Gong, JING Xue, JIANG Yueping
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血清Lp(a)联合Gensini评分对ACS患者PCI 术后短期预后的评估价值
Zhongguo shiyan zhenduanxue目的 探讨血清脂蛋白(a)(lipoproteina, Lpa)联合Gensini评分对急性冠脉综合征Acute coronary syndrome ACS)患者接受经皮冠脉介入治疗(percutaneous coronary intervention, PCI)后的短期(28天)内预测重大心血管不良事件(MACE)的临床价值，并探讨其是否可作为MACE的预测指标。方法 纳入2023年6月至2024年12月期间，于长春市中心医院行PCI的115例ACS患者，按术后28天内MACE发生与否分为MACE组 ...
付伟旭, 娄冬梅
doaj
Diagnostic value of serum origin recognition complex protein 1 in the progression of HBVrelated liver fibrosis [PDF]
Objective To explore the diagnostic value and significance of human serum origin recognition complex protein 1 (ORC1) in the degree of hepatitis B (HBV)-related liver fibrosis. Methods A total of 269 patients with HBV infection admitted to the Department
HU Bobin +9 more
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