Results 51 to 60 of about 1,424 (159)
基质金属蛋白酶在口腔黏膜癌变过程中的表达及临床意义 [PDF]
, 2002 摘 要:【目的】观察基质金属蛋白酶-2(MMP-2)、基质金属蛋白酶-9(MMP-9)和基质金属蛋白酶抑制因子-2(TIMP-2) 在口腔黏膜白斑及其癌变组织中的表达, 推断MMP 在白斑癌变过程中的作用。【方法】通过免疫组织化学的方法检测22 例 白斑, 7 例白斑癌变组织以及14 例正常黏膜组织中MMP-2、MMP-9 及TIM P-2 表达的情况。【结果】白斑癌变组的MMP-2 、 MM P-9 表达阳性率分别为85.7 %、100 %, 均高于正常组(P 0.05), MMP-9 ...
潘朝斌, 蔡华雄
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Survival differences between endoscopic treatment and surgical treatment for patients with T1-2N0M0 duodenal neuroendocrine tumor [PDF]
ObjectiveTo compare the long-term survival outcomes of patients with T1-2N0M0 duodenal neuroendocrine tumor (DNET) after endoscopic resection (ER) or surgical resection (SR).
Bin BAI +5 more
core +1 more source
Zhongguo shiyan zhenduanxue, 2008 目的探讨埃兹蛋白（Ezrin）在食管鳞癌组织中的表达及其在诊断食管鳞癌中的价值.方法选择手术切除并经组织病理学检查确诊的食管癌组织标本及癌旁正常组织标本76例,应用免疫组织化学SP法检测Ezrin的表达,并分析Ezrin表达与食管癌患者年龄、性别、病变长度、分化程度、浸润深度和有无淋巴结转移等临床病理因素的相关关系。结果Ezrin阳性表达率在食管癌组织为90.7%,癌旁正常组织为46.1%,两者间差异有统计学意义（χ2=51.05,P0.05）;Ezrin表达与食管癌浸润深度有关（χ2=4.47 ...
翟建文 +3 more
doaj
[Chidamide inhibits proliferation and promotes apoptosis of esophageal squamous cell carcinoma cells by inhibiting the PI3K/Akt and ERK1/2 pathways and increasing DNA damage]. [PDF]
Nan Fang Yi Ke Da Xue Xue Bao, 2023 Gao M, Zhao B, Yang W, Tang J, Liu Y.
europepmc +1 more source
, 2003 目的 测定三叶因子 1(TFF1)在正常及病理条件下胃黏膜中的表达情况 ,探讨TFF1在胃黏膜损伤修复及胃癌抑制中的作用及意义。方法 应用免疫组化方法测定正常及不同病理条件下胃黏膜中TFF1的表达情况 ,通过图像分析软件分析阳性信号平均吸光度值以了解其表达情况。结果 胃炎、胃溃疡及十二指肠球部溃疡患者TFF1表达明显高于正常胃黏膜 (0 .5 1± 0 .0 5 ,0 .5 1± 0 .0 6 ,0 .5 0± 0 .0 6比 0 .4 4± 0 .0 6 ;P值均 0 .0 5 )。结论 ...
任建林 +8 more
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Short-term efficacy of endoscopic submucosal dissection for early carcinoma in the remnant stomach [PDF]
ObjectiveTo explore the short-term efficacy of endoscopic submucosal dissection (ESD) in the treatment of early carcinoma in the remnant stomach. Methods A retrospective study was conducted on 45 patients with early residual gastric cancer underwent ESD ...
Baisheng CHEN +9 more
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Zhongguo shiyan zhenduanxue, 2007 目的观察HLA-G在食道鳞癌组织和癌旁组织中的表达情况,探讨HLA-G在食道鳞癌中表达的临床意义。方法应用免疫组化S-P法,对47例食管癌及其癌旁组织中HLA-G的表达进行免疫组化染色。结果HLA-G在食道鳞癌组织和癌旁组织中表达率分别为78.7%、0%。癌组织中HLA-G主要表达于肿瘤细胞胞浆中。HLA-G的表达与肿瘤大小、浸润程度、病理学分级及淋巴节转移状况无关。结论HLA-G在食道鳞癌中有显著表达,且其表达主要由肿瘤细胞产生。
杨新玲 +4 more
doaj
Inhibition of Proliferation of Esophageal Cancer Cells by Fucoidan Based on Nrf2/ROS Signaling Pathway [PDF]
Objective: To explore the effect of fucoidan on esophageal cancer and analyze its mechanism. Methods: MTT assay was used to analyze the inhibition rate of cell proliferation, Hoechst33258 staining and flow cytometry were used to detect cell apoptosis ...
Hua WU +4 more
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Zhongguo shiyan zhenduanxue, 2020 食管癌为常见的恶性肿瘤之一,临床早期不易被发现,具有较高的发病率和死亡率。研究表明当人体消化系统出现病变时,机体内相关血清指标会随之而改变[1-3]。本文通过监测食管癌患者手术前后血清中鳞状细胞癌抗原(SCC)、癌胚抗原(CEA)、糖类抗原199(CA199)、细胞角蛋白19片段(CYFRA21-1)四种肿瘤标志物水平的变化,探讨以上肿瘤标志物对食管癌诊断以及预后判断的评估价值。
李春霖 +9 more
doaj
Advances in molecular mechanisms of cancer origin and early tumorigenesis [PDF]
A comprehensive understanding of the key molecular events underlying the origin and early evolution of malignant tumors is crucial for cancer prevention, early diagnosis, and the development of intervention strategies.
LIN Dongxin, XIAO Xinyi
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