Results 61 to 70 of about 815 (100)

异类叶升麻苷调控PI3K/Akt/mTOR通路抑制人食管鳞状癌ECA109细胞增殖及迁移的机制研究

Zhongguo shiyan zhenduanxue
目的探究异类叶升麻苷基于PI3K/Akt/mTOR信号通路抑制人食管鳞状癌ECA109细胞增殖及迁移的作用机制。方法采用不同浓度异类叶升麻苷处理ECA109细胞，通过CCK-8与克隆形成实验评估细胞增殖活性；根据CCK-8检测结果分为对照组和异类叶升麻苷低（150 μM）、中（300 μM）和高（400 μM）剂量组，通过划痕愈合实验评估细胞迁移能力，Western blot检测细胞PI3K p85、p-PI3K、Akt、p-Akt、mTOR、p-mTOR 蛋白表达及磷酸化水平，RT ...
宋文潇, 孙鹏, 孙少林, 张乐宁, 贾春祎   +4 more
doaj  

[Clinical observation of free rectus femoris flap for repair of surgical defect in pharyngo-laryngeal malignant tumor]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Li W, Chen Z, Wang J, Lan X, Pura Z, Xiong X, Yang L.   +6 more
europepmc   +1 more source

血浆外泌体LncRNA POU3F3与SCCA联合检测对食管鳞癌早期诊断及淋巴结转移风险预测的价值

Zhongguo shiyan zhenduanxue
目的探讨血浆外泌体长链非编码RNA 八聚体结合蛋白3（LncRNA POU3F3）与鳞状细胞癌抗原（SCCA）单项及联合检测在食管鳞状细胞癌（ESCC）早期诊断和淋巴结转移（LNM）风险预测中的临床价值。方法选取120例ESCC患者（其中淋巴结转移组68例，无转移组52例）和60例健康体检者。采用RTq-PCR技术检测血浆外泌体中LncRNA POU3F3的表达水平，化学发光法检测血浆SCCA浓度。通过受试者工作特征（ROC）曲线评估各指标及联合检测的诊断与预测效能。结果ESCC组血浆外泌体lncRNA
张军伟, 庞世杰, 魏晓红, 王军民   +3 more
doaj  

[Research Progress on the Role and Mechanisms of PYCR1 
in Tumorigenesis and Progression]. [PDF]

Zhongguo Fei Ai Za Zhi
Meng Y, Yang Z, Feng H, Li H, Li B.
europepmc   +1 more source

[The Clinical Application and Development of Tumor Biomarkers in China]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Wang C.
europepmc   +1 more source

倾向性评分匹配法对胸段食管鳞癌同期放化疗方案的再评价

Zhongshan Daxue xuebao. Yixue kexue ban, 2015
摘 要: 【目的】 经倾向性评分匹配法(PSM)均衡组间协变量后,对比多西紫杉醇联合顺铂化疗(DP组)同步放疗与顺铂联合氟尿嘧啶化疗(PF组)同步放疗治疗中晚期食管癌的疗效并探讨其预后因素?【方法】 回顾性分析2000年1月至2011年12月共178例就诊于高州市人民医院的中晚期食管癌患者的临床资料,其中DP组79例,PF组99例?对两组患者资料进行倾向性匹配分析,得到组间协变量均衡的样本,并利用新样本作生存分析?【结果】 两组共67对匹配成功, DP组(n = 67)和PF组(n = 67 ...
doaj  

[Exploration of clear surgical margin in human papillomavirus positive oropharyngeal cancer treated with transoral robotic surgery]. [PDF]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Gong H, Xu C, Wu C, Cao P, Chen Y, Wu J, Shi M, Zhang M, Zhou L, Tao L.   +9 more
europepmc   +1 more source

[Role of Receptor Tyrosine Kinase AXL in Cancer Targeted Therapy Drug Resistance]. [PDF]

Zhongguo Fei Ai Za Zhi
Zhan S, Chen P, Lv T, Song Y.
europepmc   +1 more source

[Application of Explainable Deep Learning in Differentiating Benign from Malignant 
Pulmonary Space-occupying Lesions and Classifying Pathological Subtypes of Lung Cancer]. [PDF]

Zhongguo Fei Ai Za Zhi
Li H, Wang Y, Wang Y, He H, Li J, Su Y, Kong F, Liu X, Cheng L, Li Y.   +9 more
europepmc   +1 more source

[A Case of Metastatic Non-small Cell Lung Cancer with Rare BRAF p.L485_T488delinsF Mutation Treated with Dabrafenib and Trametinib]. [PDF]

Zhongguo Fei Ai Za Zhi
Wang Y, Zhao W, Yang C, Zhang R, Wang C, Han C, Li J.   +6 more
europepmc   +1 more source