Results 11 to 20 of about 9,041 (170)
Value of 18F-PSMA PET/MRI for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy [PDF]
Objective: To investigate the value and significance of 18F-prostate-specific membrane antigen (18F-PSMA)-1007 PET/MR for early diagnosis of recurrence and metastasis in prostate cancer patients after radical prostatectomy (RP).
ZHOU Yilei, ZHANG Miao, GUO Rui, ZHOU Jinxin, LI Biao, LI Xiang
core +1 more source
Review of role of fatty acid binding protein-4 in obesity-associated tumors [PDF]
Obesity is one of the major factors threatening human health. Excessive fat accumulation not only has detrimental effects on human metabolism and cardiovascular system, but also is highly correlated to the incidence and mortality of various tumors. Fatty
FENG Ming, MENG Jian, WU Ruifang
core +1 more source
双膦酸盐是用于骨骼疾病及钙代谢性疾病治疗的一类药物,主要用于治疗骨质疏松症、佩吉特病、高钙血症等。同时临床研究显示双膦酸盐还可用于多发性骨髓瘤、乳腺癌、肾癌、前列腺癌等疾病的辅助治疗,改善患者的临床结局,尤其是唑来膦酸盐的抗肿瘤效果更具优势,被广泛应用于多种恶性肿瘤的临床研究。本文就双膦酸盐在肿瘤辅助治疗中的临床研究进展进行综述。国家自然科学基金面上项目 ...
何斌 +4 more
core +1 more source
目的本研究通过第二代高通量测序(NGS)检测配对骨肉瘤转移灶和原发灶标本,分析骨肉瘤原发灶与转移灶的基因图谱差异,以期发现促进骨肉瘤发生和转移的相关分子及可能机制。方法12例转移患者的原发灶与转移病灶肿瘤组织样本,使用第二代高通量测序(NGS)进行检测,其中9对panel检测(678个基因)以及3对全外显子检测(WES),分析比较骨肉瘤原发灶与转移灶的基因图谱差异:基因拷贝数变异通过EXCAVATOR检测;DNA层面的融合突变通过Lumpy检测;RNA层面的融合突变通过Defuse + STAR ...
许明贤 +4 more
doaj
Preliminary application of improved 3D printed pathological section box to assisting stitching pathological images of bone tumor [PDF]
Objective·To explore the feasibility of applying improved pathological section boxes based on image post-processing and 3D printing technology to assisting artificial intelligence (AI) in stitching pathological images of bone tumors.Methods·Bone tumor ...
AI Songtao +6 more
core +1 more source
Identification of Candidate Plasma Altered miRNA Associated with Bone Metastasis of Lung Cancer [PDF]
目的:应用高通量miRNA芯片及荧光定量PCR技术筛选及鉴定肺癌骨转移血浆中差异表达的miRNA。 方法:搜集2013至2015年在厦门大学附属第一医院入院的45例肺癌病人外周血标本。选取4例肺癌骨转移与4例肺癌无骨转移病人血浆,应用miRNA芯片技术对差异表达的miRNA进行筛选。应用IPA分析差异miRNA参入的信号通路。应用Real-timePCR检测候选差异表达miRNA,进行验证。 结果:通过比对,成功建立了肺癌骨转移与肺癌无骨转移血浆miRNA芯片表达谱,筛选出了12个差异表达miRNA ...
王文一
core
Current status and treatment direction of the immune microenvironment of castration-resistant prostate cancer [PDF]
With the rapid development of cancer immunology, more and more research focuses on the role of immune cells and signaling molecules in the tumor microenvironment. Prostate cancer is the second most common malignant tumor in men globally.
YANG Wenbo, ZHANG Bin, WU Jiahui, CUI Jie
core +1 more source
ABSTRACT Cost‐effective and efficient non‐noble‐metal catalysts for selective lignin hydrogenolysis remain elusive, representing a significant challenge in biorefinery. Here, we prepared a nitrogen‐doped carbon supported CoNi bimetallic catalyst, which was successfully derived from zeolitic imidazolate framework (ZIF) via high‐temperature pyrolysis ...
Xingwei Luo +3 more
wiley +1 more source
A Systematic Review on Different Treatment Methods of Bone Metastasis from Cancers [PDF]
Background and objective Skeletal metastase is one of the most common complications related to advanced cancer. The aim of this study is to analyze the effectiveness and safety of radiotherapy plus intravenous bisphosphonates versus radiotherapy alone ...
Jinhui TIAN +4 more
core
目的 提高晚期前列腺癌并发症的治疗水平。方法 对 42例晚期前列腺癌患者分别出现的骨痛、贫血、尿路梗阻、顽固性血尿及下肢水肿等并发症分别给予多种止痛剂、博宁、氯化锶、外放射、间断输血、经尿道前列腺电切术等治疗。结果 42例患者中 1 8例死亡 ,2 4例存活 ;结论 ...
王晓峰, 白培明
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