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Zhongshan Daxue xuebao. Yixue kexue ban, 2022 目的本研究通过第二代高通量测序（NGS）检测配对骨肉瘤转移灶和原发灶标本，分析骨肉瘤原发灶与转移灶的基因图谱差异，以期发现促进骨肉瘤发生和转移的相关分子及可能机制。方法12例转移患者的原发灶与转移病灶肿瘤组织样本，使用第二代高通量测序（NGS）进行检测，其中9对panel检测（678个基因）以及3对全外显子检测（WES），分析比较骨肉瘤原发灶与转移灶的基因图谱差异：基因拷贝数变异通过EXCAVATOR检测；DNA层面的融合突变通过Lumpy检测；RNA层面的融合突变通过Defuse + STAR ...
许明贤 +4 more
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Zhongshan Daxue xuebao. Yixue kexue ban, 1987 本文报告自1964～1981年经外科治疗的女性单侧乳腺癌1656例,随访1—18年(中位11年),有128例发生骨转移,骨转移率为7.7％。骨转移的主要部位为脊柱(46.6％),肩胛带(15.1％),骨盆带(10.9％),显示乳腺癌的骨转移与肋间——脊椎静脉系统密切相关。本组术后发生骨转移的中位时间为22个月,发现骨转移后的中位生存时间为7个月。影响乳腺癌术后骨转移的主要因素为乳腺癌的病理组织学类型及区域淋巴结转移情况。作者认为预访和减少乳腺癌骨转移率的切实可行的措施是早期发现、早期诊断、早期治疗 ...
詹友庆
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Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 评估根治性放疗后骨转移鼻咽癌患者在其骨转移病灶接受局部放射治疗的生存结果。 【方法】 选取２００１年２月至２００４年１２月期间，在中山大学肿瘤防治中心接受治疗的２３１例鼻咽癌骨转移病人纳入这项研究，分别采用单因素和多因素分析，对比有无接受骨转移病灶放射治疗病人的生存差异，并确定其独立预后因素。【结果】 与没有接受骨转移放射治疗的一组对比（中位生存时间： １５个月），接受骨转移病灶放射治疗的一组总生存时间明显延长（中位生存时间：２５个月，Ｐ ＜ ０．００１）。与年轻组（≤ ４５岁）、孤立性骨转移（
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常规调强放射治疗技术用于初诊Ⅳb期鼻咽癌骨转移的可行性研究 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2021 目的研究评估常规调强放射治疗技术用于初诊Ⅳb期鼻咽癌骨转移的可行性。方法收集15例已经采取TOMO放射治疗的初诊Ⅳb期鼻咽癌骨转移患者的计划，按照相同的临床剂量学要求，在Eclipse治疗计划系统上对靶区设置固定野的常规IMRT计划，采用滑窗技术，其中对鼻咽部位靶区设置等分角度的9野调强，骨转移靶区设置7野或者9野调强，比较分析对应计划的靶区处方剂量覆盖率、高剂量、均匀指数和适形度指数，统计部分危险器官的关键剂量指标差异，以及表征计划运行效率的机器跳数（MU）与治疗时间差异等 ...
苏灿森, 李云宝, 孙文钊
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马蔺子素对153Sm-EDTMP 治疗鼻咽癌骨转移瘤的影响 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 1998 目的: 探讨马蔺子素提高钐-153 乙二胺四甲撑膦酸( 153 Sm-EDTMP)治疗鼻咽癌(NPC)骨转移的可能性。 方法: NPC 多发性骨转移瘤 40 例,随机分为153Sm-EDTMP 内照射治疗组和马蔺子素与153Sm-EDTMP 联合治疗组各 20 例。结果: 单纯内放疗组显效率为 35%,联合治疗组显效率为 75%;肿瘤无进展生存时间分别为( 3. 8±2. 0)月和( 7. 6±3. 1)月, 2 组比 较差异有显著性(P 0. 05)。结论: 马蔺子素可 以提高153 Sm-EDTMP
樊 卫 曾宗渊
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Equine Veterinary Journal, Volume 55, Issue 2, Page 261-269, March 2023., 2023 Summary Background In clinical practice, early diagnosis of Equine Odontoclastic Tooth Resorption and Hypercementosis (EOTRH) and other resorptive incisor diseases is difficult to achieve. The radiographic appearance of subtle pathological changes has not been described in detail and might be confused with age‐related changes.
Louisa Albers +4 more
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Rare Metals, Volume 45, Issue 8, August 2026.ABSTRACT The electrocatalytic co‐reduction of CO2 and nitrate (NO3− ${\text{NO}}_{3}^{-}$) to synthesize urea presents a sustainable alternative to traditional industrial processes, yet its efficiency is fundamentally limited by the kinetically mismatched activation and coupling of CO2 and NO3− ${\text{NO}}_{3}^{-}$.
Jiayu Liu +9 more
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Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Mechanical dynamic sealing components are usually subjected to the erosion of a hydrothermal environment; thus, the selected service materials must meet stringent requirements for superior self‐lubrication, corrosion resistance, and thermal stability.
Yanchun Zhao +8 more
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Rare Metals, Volume 45, Issue 6, June 2026.ABSTRACT The development of structurally stable anodes with high capacities and long cycle lives is essential for the development of potassium–ion batteries. Conversion‐type anodes have attracted considerable attention in potassium–ion batteries (PIBs) due to their high theoretical capacities.
Jeong Ho Na +7 more
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Rare Metals, Volume 45, Issue 4, April 2026.ABSTRACT Bismuth anode materials are considered promising anode candidates for sodium–ion batteries (SIBs) due to their high theoretical capacity and appropriate working potential. Nevertheless, the significant volume expansion that occurs during the cycling process restricts its broader application in sodium–ion storage. Herein, Bi/Bi2O3 nanoparticles
Jiaju Lu +3 more
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