'I'm Stronger and Healthier. Yeah, and More Fit' Young Strong and Deadly Program Process Evaluation. [PDF]
Fraser A +6 more
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Characteristics and Outcomes After General Anaesthesia in Elderly Patients: A Nationwide Cohort Study. [PDF]
Risager BH +5 more
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
'I Got Dentures in, So at Least I Can Eat Now': Aboriginal and Torres Strait Islander Peoples' Perceptions of and Experiences With Removable Dentures. [PDF]
Aiyar R +6 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Executive Functions Among Kindergarteners in the Capital of Laos: Relations with Socialization Practices and Later Mathematics Skills. [PDF]
Kajiyama Y, Takahashi Y, Moriguchi Y.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The β-glucuronidase activity of ox spleen and the assay of β-glucuronidase preparations [PDF]
openaire +2 more sources
The social origins of identity and bias: Language models, accumulated meaning and positioning. [PDF]
Durrheim K.
europepmc +1 more source

