Results 91 to 100 of about 10,486,500 (294)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Disease Burden of Osteoarthritis in the World, China, and Regions with Different Socio-demographic Index from 1990 to 2021 [PDF]
Zhongguo quanke yixueBackground Osteoarthritis (OA) seriously endangers the physical and mental health of patients. Currently, systematic studies on the disease burden of OA are limited.
CHEN Xingchao, GAO Zhenhua, XU Shenggang, ZOU Yonggang, QIAN Jun, WEI Jiantong
doaj +1 more source
, 2006 This trifold brochure explains the MY NASA DATA project for K-12 educators and citizen scientists. The brochure covers topics such as What is a microset? What kind of microsets are available? Sample Graphs. Educational Resources and Standards.
Lin Chambers
core
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
A picture paints 5 000 (pages of) words
South African Journal of Radiology, 2000 No abstract available.
Russel Whitehorn
doaj +1 more source
Journal of the American Geriatrics Society, 2019 This commentary comments on the article by Anthony Back et al .
openaire +2 more sources
Creating Reusable Educational Components: Lessons from DLESE [PDF]
, 2002 Reuse of educational materials is integral to many educator tasks, from designing a course to preparing for a lab or class. This article describes a study on the reuse of educational materials in the context of the Digital Library for Earth System ...
Holly Devaul +2 more
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Engagement in Authentic Geoscience Research: Evaluation of Research Experiences of Undergraduates and Secondary Teachers [PDF]
, 2003 This article examines the effects of a program involving authentic research on the participants' interest in research, career plans, and attitudes on science.
Olga Jarrett, Pamela Burnley
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source