Results 101 to 110 of about 1,034,135 (309)

Trends in tuberculosis incidence and mortality and risk factors for death in the Belt and Road partner countries from 1990 to 2021: based on GBD 2021 database

Zhongguo gonggong weisheng
ObjectiveTo understand the trends in tuberculosis (TB) incidence and mortality and the main risk factors for TB deaths in Belt and Road Initiative (BRI) partner countries from 1990 to 2021, thus providing a reference for the rational allocation of health
Yaping LIU, Lin WU, Junping LIU, Yue ZHOU, Xinle YIN, Yiyan TANG, Lihan ZHANG, Yunkai LI, Juan GUAN, Yanfu WANG, Libo LIANG   +10 more
doaj   +1 more source

Igualada: ortofotomapa 1:5 000

, 2018
1 ortofotomapa, imprès, color. Forma part d'un projecte de cartografiar totes les capitals de comarca de la província de Barcelona. Es van fer fotografies aèries en color a escala 1:10 000 de més de 25 nuclis de la província (1974-1977). A l'any 1976 es
Diputació de Barcelona. Servei de Cartografia i Fotogrametria
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Vilafranca del Penedès: ortofotomapa 1:4 000

, 2018
1 ortofotomapa, imprès, color. Forma part d'un projecte de cartografiar totes les capitals de comarca de la província de Barcelona. Es van fer fotografies aèries en color a escala 1:10 000 de més de 25 nuclis de la província (1974-1977). A l'any 1976 es
Diputació de Barcelona. Servei de Cartografia i Fotogrametria
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Venezuela 1:50 000. Series E784: Sheet 6647 II: Cuyagua

, 2012
1 full de la sèrie Venezuela 1:50 000 de la TCP. - Al verso hi ha un anunci comercial d'una empresa índia: Ajanta Fireworks1:50 00037 x 55 cm, en full 49 x 73 ...
Estats Units d'Amèrica. US Army, Topographic Command
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source