Results 111 to 120 of about 1,034,135 (309)

Carte de l'Afrique à l'échelle de 1: 2 000 000. 01, Alger : Afrique (région septentrionale) / dressé et dessiné par... Régnauld de Lannoy de Bissy

, 1887
Échelle(s) : 1:2 000 ...
France. Service géographique de l'armée. Éditeur scientifique, Régnauld de Lannoy de Bissy, Richard de (1844-1906). Cartographe   +1 more
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Prevalencia del síndrome metabólico en pobladores peruanos por debajo de 1 000 y por encima de los 3 000 msnm

Anales de la Facultad de Medicina, 2012
Objetivos: Determinar y comparar la prevalencia del síndrome metabólico y de sus diferentes componentes en población adulta peruana que habita por debajo de 1 000 y por encima de 3 000 msnm.
Jaime Pajuelo, José Sánchez-Abanto, Harold L. Torres, Marianella Miranda   +3 more
doaj  

Carte de l'Afrique à l'échelle de 1:2 000 000. 30, Berbéra : Afrique (région équatoriale) / dressé et dessiné par... Régnauld de Lannoy de Bissy

, 1887
Échelle(s) : 1:2 000 ...
France. Service géographique de l'armée. Éditeur scientifique, Régnauld de Lannoy de Bissy, Richard de (1844-1906). Cartographe   +1 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Carte de l'Afrique à l'échelle de 1:2 000 000. 08, Le Caire : Afrique (région septentrionale) / dressé et dessiné par... Régnauld de Lannoy de Bissy

, 1886
Échelle(s) : 1:2 000 ...
France. Dépôt de la guerre. Éditeur scientifique
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Carte de l'Afrique à l'échelle de 1:2 000 000. 03, Funchal : Afrique (région septentrionale) / [dressé et dessiné par... Régnauld de Lannoy de Bissy]

, 1902
Échelle(s) : 1:2 000 ...
France. Service géographique de l'armée. Éditeur scientifique, Régnauld de Lannoy de Bissy, Richard de (1844-1906). Cartographe   +1 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source