Results 121 to 130 of about 1,047,701 (287)

Does Patient Experience Correlate With Overall Hospital Quality Ratings? [PDF]

J Patient Exp
Badr S, Nahle T, Rahman S, Al Soueidy A, Stefaniak M, Burden M, Rachoin JS.   +6 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Socioeconomic differences in the prevalence, treatment and control of major cardiometabolic risk factors by sex: a cross-sectional study of the UK Biobank. [PDF]

BMJ Public Health
Kelly RK, Harris K, Muntner P, Woodward M.   +3 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The role of visceral obesity surrogate markers in predicting cardiovascular disease: Insights from the CHARLS study. [PDF]

Medicine (Baltimore)
Guo P, Liu Y, Chen G, Jiang Y.
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Christ aux 200 000 bras (camp d’Argelès-sur-Mer)

Cahiers de Civilisation Espagnole Contemporaine, 2017
Rose Duroux
doaj   +1 more source

Hospitalization Burden Estimates of Respiratory Syncytial Virus With Adjustment for Case Underascertainment in Adults Aged 18 to 65 Years in High-Income Countries: A Systematic Review, Meta-Analysis, and Modeling Study. [PDF]

Open Forum Infect Dis
Li Y, Kenmoe S, Begier E, Wahi-Singh P, Wahi-Singh B, Branche AR, Walsh EE, Liang C, Sato R, Gessner BD, Nair H.   +10 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Benchmarking the urinary transplant metabolome of kidney transplant recipients using healthy organ donors. [PDF]

Front Transplant
Shehab NBN, Lammers-Jannink KCM, Riphagen MH, Eskandari SK, Azzi JR, de Borst MH, Bunte K, Bakker SJL, Heiner-Fokkema MR.   +8 more
europepmc   +1 more source