Results 141 to 150 of about 10,198,141 (356)

Earth Matters! [PDF]

open access: yes, 2007
This module features classification activities that will lead students from simple sorting of familiar objects to classifying materials into liquids, gases, and solids.
Keri Garver-Hallau
core  

Overcoming the Limitations of an Urban Setting Through Field-based Earth Systems Inquiry [PDF]

open access: yes, 2004
Disconnection between students and nature in an urban setting thwarts student engagement and impedes geoscience teaching and learning. Conducting field trips is one way to engage students, but the urban environment does not provide an ideal setting with ...
Stuart Birnbaum
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Rising Tides [PDF]

open access: yes, 2007
This journal consists of current oceanography research conducted by NASA, NOAA, and university researchers and educators at NASA It features a collection of articles, classroom activities, readings, teacher/student questions, imagery and more designed ...
Brian Campbell
core   +1 more source

Groups of order at most 6 000 generated by two elements, one of which is an involution, and related structures [PDF]

open access: yesarXiv, 2015
A (2,*)-group is a group that can be generated by two elements, one of which is an involution. We describe the method we have used to produce a census of all (2,*)-groups of order at most 6 000. Various well-known combinatorial structures are closely related to (2,*)-groups and we also obtain censuses of these as a corollary.
arxiv  

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

open access: yesMolecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan   +6 more
wiley   +1 more source

Aster's Hoity Toity Belt [PDF]

open access: yes, 2005
This fictitious story centers on a celestial family of asteroids and their adventures in the "skyborhood." Students will learn about smaller bodies of our solar system and the Dawn mission by identifying some aspects of the story that are true, some that
Jacinta Behne
core  

Long-term impact of HPV vaccination and COVID-19 pandemic on oropharyngeal cancer incidence and burden among men in the USA: A modeling study

open access: yesThe Lancet Regional Health. Americas, 2022
Summary: Background: Oropharyngeal cancer (OPC) incidence is rising rapidly among men in the United States of America (USA). We aimed to project the impact of maintaining the current HPV vaccination uptake and achieving 80% national (Healthy People ...
Haluk Damgacioglu   +6 more
doaj  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

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