Results 71 to 80 of about 10,486,500 (294)

The Development of Student Conceptions of the Earth-Sun Relationship in an Inquiry-Based Curriculum [PDF]

open access: yes, 2007
Provides pedagogical insight concerning learners' pre-conceptions and misconceptions about the earth's rotation and the seasons The resource being annotated is: http://www.dlese.org/dds/catalog_SERC-NAGT-000-000-000-644 ...
Lamont-Doherty Earth Observatory, Columbia University
core  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Fermi Paper Model (Formerly GLAST Paper Model) [PDF]

open access: yes, 2009
This paper model provides a short description of the scientific instruments on board GLAST as well as links to other resources about the GLAST instruments. There is also a short description of how GLAST detects gamma-rays with the Large Area Telescope as

core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

КІЛЬКІСНА ХАРАКТЕРИСТИКА ВЛАСНИХ НАЗВ МАТЕРІАЛЬНИХ ОБ’ЄКТІВ

open access: yesЗаписки з українського мовознавства, 2019
У статті з’ясовано, що загальна кількість прагматонімів становить 2 006 000, проте лише 70 000 можуть функціонувати як одиниці мови. Найбільше засвідчено власних назв будинків і подібних споруд (1 260 000), товарів (300 000) і окремих предметів (260 000).
М. М. Торчинський
doaj   +1 more source

Our Mission to Planet Earth: A Guide to Teaching Earth System Science [PDF]

open access: yes, 1994
This teaching guide provides hands-on activities and information related to studying the Earth system. Its primary goal is for children to become familiar with the concept of cycles and to learn that some human activities can cause changes in their ...

core  

Using Concept Maps to Plan an Introductory Structural Geology Course [PDF]

open access: yes, 2004
This report presents the results of incorporating constructivist methods, including concept maps, into an undergraduate structural geology curriculum. A concept map is a visual representation of concepts and their relationship to each other in a body of ...

core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

The Core of Omega Centauri (NGC 5139) Lithograph and In Search of...Stellar Evolution Classroom Activity [PDF]

open access: yes, 2010
This Hubble Space Telescope image reveals a small region inside the massive globular cluster Omega Centauri, which boasts nearly 10 million stars. This colorful assortment of 100,000 stars residing in the crowded core of the cluster is one of the first ...

core  

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