Results 91 to 100 of about 193,004 (295)
Advanced Science, EarlyView.This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng +15 more
wiley +1 more source
Genetic analysis and mapping of ascochyta blight resistance in kabuli chickpea (Cicer arietinum)
The Indian Journal of Agricultural SciencesAscochyta blight is a fungal disease of chickpea (Cicer arietinum L.) caused by Ascochyta rabiei, resulting in up to 100% crop yield loss under favourable conditions.
LOVEPREET KAUR +7 more
doaj +1 more source
Advanced Science, EarlyView.Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
POS-004 ATYPICAL HEMOLYTIC UREMIC SYNDROME IN YOUNG FEMALE: CASE FOR DISCUSSION
, 2022 W.A.E.S. Elrewaihby
openalex +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
Advanced Science, EarlyView.OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Advanced Science, EarlyView.A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen +9 more
wiley +1 more source
Broadband All‐Optical Memtransistor Based on Organic Cocrystals for Noise‐Robust Motion Recognition
Advanced Science, EarlyView.This work presents an all‐optical synaptic transistor using DTT‐TCNQ organic charge transfer cocrystals, achieving broadband bidirectional modulation (395–808 nm) with highly linear synaptic plasticity (nonlinearity coefficients αp = 0.00191, αd = 0.00305).
Zhaohui Cai +8 more
wiley +1 more source
Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias
Advanced Science, EarlyView.Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei +32 more
wiley +1 more source