Results 151 to 160 of about 11,521 (228)

Insights into Graphene Nanostructures, Fabrication Techniques, Mechanical, and Functional Behavior Characterization

Small Science, EarlyView.
This review comprehensively explores the structural configurations, properties, and applications of graphene variants—including monolayer, multilayer, and functionalized forms (graphene oxide, rGO, composites). It discusses fabrication techniques (mechanical exfoliation, chemical vapor deposition, epitaxy) and advanced mechanical characterization ...
Ashfaqul Hoque Khadem, Camili Brignoni Diaz, Lihua Lou   +2 more
wiley   +1 more source

Recent Synthetic Advances in C–H/N–H Functionalization of 1H‐Pyrazoles: Diverse Strategies Across Variously Substituted Scaffolds

The Chemical Record, EarlyView.
Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür, Asta Žukauskaitė, Algirdas Šačkus, Eglė Arbačiauskienė   +3 more
wiley   +1 more source

Coordination Studies of a Triazole‐Substituted 3H‐1,2,4‐Diazaphosphole: CC and CN Bond Activation Induced by Cobalt(0) and Nickel(0) Complexes

Zeitschrift für anorganische und allgemeine Chemie, EarlyView.
Reactions of a triazole‐substituted 3H‐1,2,4‐diazaphosphole with electron‐rich cobalt and nickel complexes result in the selective cleavage of CC and CN bonds on the triazole, forming chelate complexes with the activated diazaphosphole ligand. The reactivity of the recently reported 3H‐1,2,4‐diazaphosphole 1 toward electron‐rich Ni and Co complexes ...
Sebastian Hauer, Gábor Balázs, Justus Reitz, Max M. Hansmann, Robert Wolf   +4 more
wiley   +1 more source

Molecular Docking Studies and In silico ADMET analysis of 1, 4 disubstituted, 1, 2, 3 Triazole Derivatives as Hemagglutinin and Neuraminidase inhibitors for Antiviral Activity against H1N1 Influenza Virus [PDF]

1,2,3-triazole is a basic aromatic heterocyclic scaffold that is used in a variety of drug discovery applications, including anticancer, anti-inflammatory, antiviral, anti-convulsant, anti-tubercular, antimicrobial, and antidiabetic. 1, 4 Disubstituted 1,
Pavankumar D Chopade, Anwar Rafique Shaikh
core   +2 more sources

Targeting Plasmodium Falciparum Asexual and Sexual Stages with Melatonin‐Based Indole Compounds

ChemistrySelect, Volume 10, Issue 41, November 3, 2025.
This study presents a comprehensive pipeline for screening melatonin‐inspired compounds synthesized via copper(I)‐catalyzed azide‐alkyne cycloaddition (CuAAC) “Click Chemistry” against Plasmodium falciparum. The pipeline evaluates activity against asexual and sexual stages, cytotoxicity, and potential interference with parasite melatonin signaling ...
Abhinab Mohanty, Lamark Carlos I, Euzébio Guimarães Barbosa, Alessandro Kappel Jordão, Celia R. S. Garcia   +4 more
wiley   +1 more source

Thiamine hydrochloride aided mechanochemical reaction: An efficient synthesis of Aryl-1,2,3-triazoles in copper ball milling conditions

Sustainable Chemistry for the Environment
The current study investigates the catalytic efficacy of the natural organo-catalyst Vitamin B1 (Thiamine Hydrochloride i.e. VB1) in the synthesis of Aryl-NH-1,2,3-Triazoles utilizing Cu ball milling conditions.
Pankaj V. Ledade, Jitendra K. Gunjate, Twinkle S. Wankhede, Sami H. Mahmood, Trimurti L. Lambat   +4 more
doaj   +1 more source

Amidine Syntheses from Classic to Contemporary for Medicinal Lead Compounds and Natural Products

European Journal of Organic Chemistry, Volume 28, Issue 40, October 29, 2025.
A revolution is underway in the synthesis of amidines with new methods unlocking complex, highly substituted amidines or closely related derivatives such as N‐sulfonyl amidines. This review surveys recent advances in amidines and related compounds, including methods to install them and bioactive molecules prominently featuring the amidine functionality.
Wyatt R. Swift‐Ramirez, Gregory A. Weiss   +1 more
wiley   +1 more source

Mannose‐Inspired Mesoionic Carbenes: Building Antitumor Palladium(II) Allyl Complexes

European Journal of Inorganic Chemistry, Volume 28, Issue 29, October 16, 2025.
Mannose‐inspired mesoionic carbenes: Building antitumor palladium(II) allyl complexes. A series of palladium(II) complexes bearing mannose‐conjugated mesoionic carbenes has been synthesized and fully characterized. Several of these compounds exhibit potent and selective antiproliferative activity against cisplatin‐resistant ovarian and colon cancer ...
Giovanni Tonon, Martina Scianna, Isabella Caligiuri, Flavio Rizzolio, Fabiano Visentin, Thomas Scattolin   +5 more
wiley   +1 more source

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, Volume 20, Issue 20, October 15, 2025.
Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Synthesis of 1,2,3-triazoles using Grignard reactions through the protection of azides. [PDF]

Front Chem, 2023
Namioka R, Suzuki M, Yoshida S.
europepmc   +1 more source