Results 41 to 50 of about 45,356 (184)

Semicarbazone and Thiosemicarbazone of 5-acetyl-3-(methylsulfanyl)-1,2,4-triazine

open access: yes, 2005
Semicarbazone as well as thiosemicarbazone of 5-acetyl-3-(methylsulfanyl)-1,2,4-triazine were synthesised as reactive intermediates for the synthesis of 1H-pyrazolo[4,3-e][1,2,4]triazine derivatives via acid promoted ring closure [1,2,3].[...
Mariusz Mojzych, Mariusz Mojzych
core   +1 more source

Nitrogen‐Rich 5,5′‐Azotetrazolates: A Broad Spectrum of Technologically Accessible Gas‐Generating Pyrotechnic Materials

open access: yesChemistryOpen, Volume 15, Issue 9, September 2026.
A series of ten 5,5′‐azotetrazolate salts with nitrogen‐rich bases is prepared and assessed as technologically accessible gas‐generating materials. Structural, safety, and ballistic evaluations reveal several compounds combining high bulk density, acceptable sensitivities, and favorable gas‐generation performance, highlighting the potential of ...
Adam Votýpka   +8 more
wiley   +1 more source

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

open access: yesChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira   +8 more
wiley   +1 more source

Influence of diluent alkyl substitution on the extraction of Am(III) and Eu(III) by a 6,6’-bis(1,2,4-triazin-3-yl)-2,2’-bipyridine ligand dissolved in alkylated cyclohexanone Diluents [PDF]

open access: yes, 2012
Several alkylated cyclohexanones were investigated as potential diluents for the selective extraction of Am(III) from Eu(III) from nitric acid solutions by the CyMe4-BTBP ligand.
Harwood, L.M.   +9 more
core   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, Volume 26, Issue 8, August 2026.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

Synthesis and crystal structures of 6- and 8-methyl-3-phenylbenzo[e][1,2,4]triazines

open access: yesActa Crystallographica Section E: Crystallographic Communications
The synthesis and single-crystal X-ray structures of two regioisomeric Blatter radical precursors, 6-methyl-3-phenylbenzo[e][1,2,4]triazine, (I), and 8-methyl-3-phenylbenzo[e][1,2,4]triazine (II), C14H11N3, are reported.
Christos P. Constantinides   +4 more
doaj   +1 more source

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

open access: yesChemBioChem, Volume 27, Issue 13, 14 July 2026.
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne   +3 more
wiley   +1 more source

The redox transformations and nucleophilic replacements as possible metabolic reactions of the drug “Triazaverin”. The chemical modeling of the metabolic processes

open access: yesChimica Techno Acta, 2015
As a model of metabolic transformations of antiviral drug “Triazaverin” and its analogues‑2-alkylthio‑6-nitro‑1,2,4-triazolo[5,1-c][1,2,4]triazine‑7-ones 1a-d examined the oxidation of alkylthio groups to the corresponding sulfoxides 2a-d and sulfones 3a-
N. R. Medvedeva   +3 more
doaj   +1 more source

Comprehensive Phenolic Profiling and Antioxidant Evaluation of Calyx, Rind, and Edible Tissues From Non‐Astringent Persimmons (Diospyros kaki)

open access: yesChemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Tissue‐specific phenolic profiling of non‐astringent persimmons (Fuyu and Jiro) reveals substantial differences in phytochemical composition and antioxidant potential. Persimmon calyx exhibits the highest concentrations of bioactive compounds, highlighting its potential as a valuable by‐product for functional food and nutraceutical applications ...
Huiwen Wang   +4 more
wiley   +1 more source

Annealing 1,2,4-Triazine to Iridium(III) Complexes Induces Luminogenic Behaviour in Bioorthogonal Reactions with Stain Alkynes. [PDF]

open access: yes
Phenanthroline-type ligand containing annealed 1,2,4-triazine ring was used to prepare novel Ir(III) complexes 3 and 4. The complexes are non-luminescent but show luminogenic behaviour following inverse electron demand Diels-Alder (IEDDA) reaction with ...
Marie, Joly   +14 more
core   +2 more sources

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