Results 31 to 40 of about 51,319 (173)

Synthesis of Novel 6-Amino-Substituted-1,2,4-Triazines scaffolds as Potential Antibacterial Agents [PDF]

, 2022
MSc (Chemistry)Department of Chemistry1,2,4-Triazine and its derivatives have proven their importance in the biological world since they are used in the treatment of diseases like cancer and HIV/AIDS. Thus this project was aimed at synthesizing novel 1,2,
Mutshaeni, Fhumulani Baldwin
core  

1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives [PDF]

, 2010
Orientation of heterocyclization reactions of functionalized 1,2,4-triazines were studied by effect of substituents in 1,2,4-triazine moieties, type of the solvent used in the reaction and the temperature effect.
Reda Mohammady Abdel-Rahman, Abdel-Rahman, Reda Mohammady, Ali, Tarik El-Sayed, Magdy Ahmed Ibrahim, Makki, Mohammed Saleh Tawfik, Mohammed Saleh Tawfik Makki, Tarik El-Sayed Ali, Ibrahim, Magdy Ahmed   +7 more
core   +1 more source

Synthesis of bis[1,2,4]triazolo[4,3-b:1′,5′-d][1,2,4]triazine, a novel polynitrogenated heterocyclic system

, 2022
2-Aryl [1,2,4]triazolo[1,5-d][1,2,4]triazine-5(6H)-thiones were methylated using methyl iodide in the presence of NaOH to give the corresponding 5-methylthio derivatives.
Nasser Montazeri (11999679), Niousha Nazari (11994504), Farzaneh Tajfirooz (11999682), Majid Mommahed Heravi (9225485)   +3 more
core   +1 more source

A facile synthesis of 1,2,4-triazine fused pyrroline nitroxides as useful paramagnetic building block

Results in Chemistry
In this study, we report an efficient synthesis of 3-amino- or 3-methylsulfanyl-6-oxyl-pyrrolo[3,4-e][1,2,4] triazine radical from O -methyl protected 3,4-dioxopyrrolidine pre-nitroxide.
Yafea Mohsen, Balázs Bognár, József Jekő, Attila Bényei, Tamás Kálai   +4 more
doaj   +1 more source

Reactivity Studies of 5,6-Dimethyl- and 3,5,6-Trimethyl -1,2,4-Triazine–N4-Oxide Against Different Electrophiles

Molecules, 2000
It describes the regioselectivity studies of 5,6-Dimethyl-1,2,4-triazine-N4-oxide using different electrophiles.
H. Cerecetto, M. González, P. Saenz, G. Seoane   +3 more
doaj   +1 more source

Semicarbazone and Thiosemicarbazone of 5-acetyl-3-(methylsulfanyl)-1,2,4-triazine

, 2005
Semicarbazone as well as thiosemicarbazone of 5-acetyl-3-(methylsulfanyl)-1,2,4-triazine were synthesised as reactive intermediates for the synthesis of 1H-pyrazolo[4,3-e][1,2,4]triazine derivatives via acid promoted ring closure [1,2,3].[...
Mariusz Mojzych, Mariusz Mojzych
core   +1 more source

6-Amino-3,4-dimethyl-1,2,4-triazin-1-ium 2-anilinobenzoate–3-amino-5,6-dimethyl-1,2,4-triazine (1/1)

IUCrData, 2017
In the title molecular salt, C5H9N4+·C13H10NO2−·C5H8N4, the asymmetric unit consists of a 6-amino-3,4-dimethyl-1,2,4-triazin-1-ium cation, a 2-anilinobenzoate anion and a neutral 3-amino-5,6-dimethyl-1,2,4-triazine molecule. The typical intramolecular N..
Ramalingam Sangeetha, Kasthuri Balasubramani, Kaliyaperumal Thanigaimani, Ibrahim Abdul Razak   +3 more
doaj   +1 more source

The Reactions of Hydrazines with α-Lactams. Regiochemistry of Hydrazine Addition and Subsequent Ring Closure to N-Aminohydantoins or 1,2,4-Triazine-3,6-diones

, 2016
The Reactions of Hydrazines with α-Lactams. Regiochemistry of Hydrazine Addition and Subsequent Ring Closure to N-Aminohydantoins or 1,2,4-Triazine-3,6 ...
Robert V. Hoffman (3021594), Madhava M. Reddy (3046365), Curtis M. Klumas (3046362), Francisco Cervantes-Lee (2322364)   +3 more
core   +1 more source

3-Nitro-4-Hydroxy-7-Propargylthio-[1,2,4]Triazolo[5,1c][1,2,4]Triazine And 3-Nitro-4-Hydroxy-7-Ethylthio-[1,2,4]Triazolo[5,1c][1,2,4]Triazine with Antiviral Activity

, 2022
Изобретение относится к области органической химии, а именно к 3-нитро-4-гидрокси-1,4-дигидро-7-пропаргилтио-[1,2,4]триазоло[5,1с]-[1,2,4]триазину и 3-нитро-4-гидрокси-1,4-дигидро-7-этилтио-[1,2,4]триазоло[5,1с][1,2,4]-триазину, формул 4-5.
Chupakhin, O. N., Volobueva, A. S., Lantseva, K. S., Чупахин, О. Н., Уломский, Е. Н., Русинов, В. Л., Savateev, K. V., Zarubaev, V. V., Зарубаев, В. В., Дрокин, Р. А., Drokin, R. A., Ланцева, К. С., Rusinov, V. L., Саватеев, К. В., Волобуева, А. С., Чарушин, В. Н., Charushin, V. N., Ulomskij, E. N.   +17 more
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Structure–Activity Relationships in Methyl‐Driven Overhauser Effect DNP

Chemistry – A European Journal, EarlyView.
Dynamic nuclear polarization (DNP) was investigated in a wide array of methyl‐containing Blatter radicals to identify design principles for the synthesis of an Overhauser DNP polarizing agent. Fourteen different radicals were synthesized, which revealed that only radicals possessing sterically unhindered methyl groups in sites of high spin density were
Ananya Mukherji, Emma A. Foley, Shubha S. Gunaga, Thierry Dubroca, Mukaila A. Ibrahim, Jin‐Seok Yi, Nisreen Sharara, Syed Raza, Fadwat Bazzi, Simona Marincean, Dragos F. Flesariu, Panayiotis A. Koutentis, Frédéric Mentink‐Vigier, Takeshi Kobayashi, Christos P. Constantinides, Frédéric A. Perras   +15 more
wiley   +1 more source