Results 21 to 30 of about 2,785 (181)
Strain‐Promoted Reaction of 1,2,4‐Triazines with Bicyclononynes [PDF]
AbstractStrain‐promoted inverse electron‐demand Diels–Alder cycloaddition (SPIEDAC) reactions between 1,2,4,5‐tetrazines and strained dienophiles, such as bicyclononynes, are among the fastest bioorthogonal reactions. However, the synthesis of 1,2,4,5‐tetrazines is complex and can involve volatile reagents.
Horner, KA, Valette, NM, Webb, ME
openaire +3 more sources
It describes the regioselectivity studies of 5,6-Dimethyl-1,2,4-triazine-N4-oxide using different electrophiles.
H. Cerecetto +3 more
doaj +1 more source
6-Amino-3,4-dimethyl-1,2,4-triazin-1-ium 2-anilinobenzoate–3-amino-5,6-dimethyl-1,2,4-triazine (1/1)
In the title molecular salt, C5H9N4+·C13H10NO2−·C5H8N4, the asymmetric unit consists of a 6-amino-3,4-dimethyl-1,2,4-triazin-1-ium cation, a 2-anilinobenzoate anion and a neutral 3-amino-5,6-dimethyl-1,2,4-triazine molecule. The typical intramolecular N..
Ramalingam Sangeetha +3 more
doaj +1 more source
The compound (±)-12aR-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione is the intermediate of baloxavir marboxil.
Yiyun Wang +6 more
doaj +1 more source
2-(5,6-Diphenyl-1,2,4-triazin-3-yl)aniline
The title compound, C21H16N4, obtained under standard Suzuki cross-coupling conditions, is a model compound in the synthesis and biological activity evaluation of new aza-analogues of sildenafil containing a pyrazolo[4,3-e][1,2,4]triazine system.
Mariusz Mojzych +2 more
doaj +1 more source
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Heteropolyacides as green and reusable catalysts for the synthesis of [3,4-b][1,3,4] thiadiazines
Synthesis of [3,4-b][1,3,4]thiadiazines from the condensation of 4-amino-6-methyl-3-thioxo-1,2,4-triazine-5(2H)-one (AMTTO) or 4-amino-1,4-dihydro-5-methyle-1,2,4-triazole-5-thione (AMTT) with phenacyl bromide in the presence of a catalytic amount of ...
F. Hakimi +3 more
doaj +1 more source
Clickable nucleoside phosphoramidites can be incorporated into oligonucleotides via solid‐phase synthesis (SPOS), enabling rapid and site‐specific post‐functionalization using bioorthogonal reactions. This review highlights their design, synthetic accessibility, and SPOS incorporation requirements, along with the kinetics and efficiency of post ...
Sébastien Depienne +3 more
wiley +1 more source
In search for highly bioactive barbituric and thiobarbituric acid derivatives, some new barbituric and thiobarbituric acids bearing 1,2,4-triazine moiety and their related systems (5–13) have been obtained from the addition of isocyanate and ...
Abeer N. Al-Romaizan
doaj +1 more source
This review provides an overview of recent developments in metal organic framework (MOF)‐based and MOF‐derived composites for efficient oxygen evolution reaction. This review also emphasizes the structural design of electrocatalyst, active site optimization, and emerging prospects of their use in practical electrolyzer systems.
Bhagyashri B. Kamble +7 more
wiley +1 more source

