Results 191 to 200 of about 13,327,440 (231)

ChemInform Abstract: Synthesis and Antimicrobial Activity of New 1,2,4‐Triazole‐3‐thiol Metronidazole Derivatives.

ChemInform, 2010
AbstractNovel metronidazole‐substituted 1,2,4‐triazole‐3‐thiole derivatives (III) and (IV) respectively are prepared and tested for their antiparasitic, cytotoxic, antibacterial, and antifungal activity.
Haythem A. Saadeh, Ibrahim M. Mosleh, Amal G. Al‐Bakri, Mohammad S. Mubarak   +3 more
openaire   +1 more source

Synthesis of 5-Ferrocenyl-4-Phenyl-4H-1,2,4-Triazole-3-Thiol and Its Derivatives

Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 1994
Abstract A ferrocenyl thiosemicarbazide was prepared by treatment of ferrocene carboxylic acid hydrazide with phenylisothiocyanate. Cyclization of the thiosemicarbazide gave the 4,5-disubstituted-4H-1,2,4-triazole-3-thiol. Alkylation of 4,5-disubstituted- 4H-1,2,4-triazole-3-thiol with methyl iodide and propyl iodide as alkylating agents led to its ...
Wu Hui, Zhang Yulan, Hu Youhong, Wu Shaozu   +3 more
openaire   +1 more source

Optimization of pyrazole-based compounds with 1,2,4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory, ulcerogenicity, cardiovascular evaluation, and molecular modeling studies.

Bioorganic chemistry (Print), 2021
Khaled R. A. Abdellatif, Eman K. A. Abdelall, H. A. Elshemy, John N. Philoppes, Emad H. M. Hassanein, Nesma M. Kahk   +5 more
semanticscholar   +1 more source

ChemInform Abstract: Highly Regioselective Heterocyclization Reactions of 1H‐1,2,4‐Triazole‐3‐thiols with Chloroacetylenephosphonates.

ChemInform, 2012
AbstractThe process takes place with high regioselectivity to produce fused heterocyclic chlorides (III).
Elena B. Erkhitueva, Albina V. Dogadina, Andrey V. Khramchikhin, Boris I. Ionin   +3 more
openaire   +1 more source

Syntheses of some novel and symmetrical bis(4-amino-4H-1,2,4-triazole-3-thiols)

Journal of Sulfur Chemistry, 2012
A series of bis(4-amino-4H-1,2,4-triazole-3-thiols) 3a–e were prepared by condensation reactions of 2,2′-(phenylmethylene)bis(sulfanediyl)diacetic acids 2a–e with thiocarbohydrazide. The starting diacid 2a–e was prepared by reactions of aromatic aldehydes 1a–e with 2-mercaptoacetic acid.
Sattar Ebrahimi, Masoomeh Sayadi
openaire   +1 more source

Regioselectivity in the glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol

Carbohydrate Research, 2009
The glycosylation of 5-(3-chlorobenzo[b]thien-2-yl)-4H-1,2,4-triazole-3-thiol (1) and its 3-benzylsulfanyl and 3-methylsulfanyl derivatives with different glycosyl halides 2-4 has been studied in presence of base. The S-glycosides 5-7 were obtained in the presence of triethylamine, whereas the respective S,N(4)-bis(glycosyl) derivatives 8-10 were ...
El Sayed H, El Ashry, Ahmed A, Kassem, Hamida M, Abdel-Hamid, Farida, Louis, Sherine A N, Khattab, Mohamed R, Aouad   +5 more
openaire   +2 more sources

Advancements in Coordination Chemistry: A Comprehensive Review on the Synthesis and Characterization of Transition Metal Complexes with 4-Amino-5-pyridyl-4H-1, 2, 4-triazole-3-thiol Ligands

SPU Journal of Science, Technology and Management Research
This review paper offers an in-depth analysis of recent advancements in coordination chemistry, specifically focusing on the production and portrayal of transition metal complexes that incorporate5-pyridyl 4-Amino-3-thiol -4H-1,2,4-triazole ligands ...
H. Patel, Himani Raval
semanticscholar   +1 more source

Electrochemical and Quantum Chemical Studies of 5-[(4-Chlorophenoxy) Methyl]-4H-1,2,4-Triazole-3-Thiol on the Corrosion Inhibition of 6061 Al Alloy in Hydrochloric Acid

Journal of Failure Analysis and Prevention, 2020
K. Raviprabha, R. Bhat
semanticscholar   +1 more source

4-Alkyl-5-aryl-4H-1,2,4-triazole-3-thiols as hypoglycemic agents

Journal of Medicinal Chemistry, 1970
M Y, Mhasalkar, M H, Shah, S T, Nikam, K G, Anantanarayanan, C V, Deliwala   +4 more
openaire   +2 more sources

Design, spectral characterization, thermal, DFT studies and anticancer cell line activities of Co(II), Ni(II) and Cu(II) complexes of Schiff bases derived from 4-amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol.

Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2015
Prateek Tyagi, Prateek Tyagi, S. Chandra, B. S. Saraswat, D. Yadav   +4 more
semanticscholar   +1 more source