Results 71 to 80 of about 84,221 (197)

Regioselectivity of the alkylation of S-substituted 1,2,4-triazoles with dihaloalkanes [PDF]

Chemistry Central Journal, 2016
1,2,4-Triazole3-thiones are good scaffolds for preparation of new lead compounds. Their derivatives attracted the attention of chemists due to their wide spectrum of biological activities. Alkylsulfanyl-1,2,4-triazoles have three nucleophilic sites (nitrogens) ready for reaction with electrophiles. Herein, new regioselective isomers were synthesized by
Axel Duerkop, Ahmed T. A. Boraei, El Sayed H. El Ashry   +2 more
openaire   +3 more sources

1-Phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone

Acta Crystallographica Section E, 2008
In the molecule of the title compound, C10H9N3O, the triazole and phenyl rings are nearly perpendicular to each other, with a dihedral angle of 88.72 (4)°. In the crystal structure, intermolecular C—H...O and C—H...N hydrogen bonds
Özden Özel Güven, Hakan Tahtacı, Simon J. Coles, Tuncer Hökelek   +3 more
doaj   +1 more source

Biological properties of the compounds formed by the combination of the 1,2,4-triazoles, furans and other functional substitutes

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. To study biological properties of the compounds formed by the combination of the 1,2,4-triazoles, furans and other functional substitutes. Methods and results.
D. M. Danilchenko, V. V. Parchenko, O. I. Panasenko, Ye. G. Knysh   +3 more
doaj   +1 more source

1H-1,2,4-Triazole-3-carboxamide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2008
Planar mol-ecules of the title compound, C(3)H(4)N(4)O, are organized into sheets by extensive N-H⋯O and N-H⋯N hydrogen bonding in the (101) plane of the crystal structure. These hydrogen bonds may also stabilize the mol-ecule in the Z form. The title compound is in the amide form, as shown by the C=O bond length [1.252 (2) Å].
openaire   +3 more sources

Physical-chemical properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-il)tio)-1-arylethanons and their reduced systems

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The aim of work is the investigation of properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanones and 2((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanols using modern physical-chemical methods.Materials and ...
O. A. Bihdan
doaj   +1 more source

The synthesis and study of physicochemical properties of 1,2,4-triazole derivatives containing the phenethyl group in position 5

Журнал органічної та фармацевтичної хімії, 2020
During the last decade, national and foreign scientists have been constantly examining an example of studying the physicochemical and biological properties of nitrogen containing heterocycles, particularly with the nucleus of 1,2,4-triazole.
Tetiana V. Ihnatova, Andriy G. Kaplaushenko, Yuliia S. Frolova   +2 more
doaj   +1 more source

Design and Synthesis of Triazole‐Based p‐tert‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu, Selahattin Bozkurt, Ozgur Ceylan   +2 more
wiley   +1 more source

Recent advances on MOF‐based colorimetric sensors

Bulletin of the Korean Chemical Society, EarlyView.
MOF‐based colorimetric sensors are widely explored due to their operational simplicity and outstanding structural tunability. In this review, the recent progress of MOF‐based colorimetric sensors is discussed, focusing on the role of MOFs in chromogenic transduction pathways.
Solmin Lee, Hyejin Yoo, Jin Yeong Kim
wiley   +1 more source

Synthesis and properties of 5-(((5-amino-1,3,4-thiadiazole-2-yl)thio)methyl)-4-phenyl-1,2,4-triazole-3-thione and its some S-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
Increased attention to thiadiazole and 1,2,4-triazole derivatives is determined by the extensive structural modification capabilities of heterocyclic system derivatives and their high pharmacological potential.
A. S. Hotsulia , S. O. Fedotov
doaj   +1 more source

In vitro cytotoxic and in vivo antitumoral activities of some aminomethyl derivatives of 2,4‐dihydro‐3H‐1,2,4‐triazole‐3‐thiones—Evaluation of their acetylcholinesterase and carbonic anhydrase enzymes inhibition profiles

Journal of biochemical and molecular toxicology, 2018
The 1,2,4‐triazole and its derivatives were reported to exhibit various pharmacological activities such as antimicrobial, analgesic, anti‐inflammatory, antitumoural, cytotoxic, and antioxidant properties. In this study, a series of triazole compounds (M1‐
İrfan Timur, Ümit M Koçyiğit, Taner Daştan, S. Sandal, A. O. Çeribaşı, Parham Taslimi, I. Gulcin, M. Koparır, M. Karatepe, M. Çiftçi   +9 more
semanticscholar   +1 more source