Results 91 to 100 of about 1,566 (134)
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New 1,2,6-thiadiazine dioxide acyclonucleosides: Synthesis and antiviral evaluation
Bioorganic & Medicinal Chemistry, 1995New acyclonucleosides derived from 1,2,6-thiadiazine dioxide systems have been synthesized. Lipase-mediated deacylation procedure was used to obtain the deprotected derivatives. All the newly prepared compounds were tested as antiviral agents, but none of them showed significant activity.
A I, Esteban +5 more
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ChemInform Abstract: Chemistry of 4‐Dicyanomethylene‐1,2,6‐thiadiazines.
ChemInform, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Panayiotis A. Koutentis, Charles W. Rees
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ChemInform Abstract: Cyclization Chemistry of 4H‐1,2,6‐Thiadiazines.
ChemInform, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Panayiotis A. Koutentis, Charles W. Rees
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An unambiguous synthesis of pyrazoles by sulphur extrusion from 1,2,6-thiadiazines
J. Chem. Soc., Perkin Trans. 1, 1981Di-imines (1) react with thionyl chloride and sulphur monochloride and dichloride giving different 1,2,6-thiadiazine S-oxides (3) and 1,2,6-thiadiazines (4), respectively. These last two compounds lead, by heating, to pyrazoles (6)via thermal extrusion of sulphur oxide or sulphur.
José Barluenga +3 more
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ChemInform Abstract: SYNTHESIS OF NEW 1,2,6‐THIADIAZINES AND 1,3,2,4‐DITHIADIAZINES
Chemischer Informationsdienst, 1984AbstractDie nach Literaturverfahren erhaltenen Schwefeldiimide (I) werden mit dem ebenfalls nach Literaturverfahren dargestellten Benzothiophendioxid (II) basisch zu den Monoac ylderivaten (III) kondensiert, die weiter basenkatalysiert zu den Thiadiazinen (IV) cyclisieren.
W. RIED, R. PAULI
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Substitution chemistry of 3,5-dichloro-4 H -1,2,6-thiadiazine 4,4-ketals
Tetrahedron Letters, 2016Abstract The reactivity of 3,5-dichloro-4H-1,2,6-thiadiazine 4,4-ketals towards nucleophilic substitution or palladium-catalyzed C–C coupling at the C-3/5 positions led to seven new 3,5-disubstituted 4H-1,2,6-thiadiazine ethylene glycol 4,4-ketals and seven 3,5-disubstituted 4H-1,2,6-thiadiazine catechol 4,4-ketals in 83–98% yields.
Kalogirou, Andreas S. +3 more
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Tautomerism of benzo- and cyclopenta-[1,2,6]thiadiazine S,S-dioxides
J. Chem. Soc., Perkin Trans. 2, 1994The synthesis and spectroscopic characterization of fused 1,2,6-thiadiazine S,S-dioxides 1–6 have been carried out. The tautomerism of this heterocyclic system has been studied by means of experimental and theoretical techniques.
Ana Castro, Ana Martínez
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Synthesis and Antiviral Activity of Modified 1,2,6-Thiadiazine Dioxide Acyclonucleosides
Nucleosides and Nucleotides, 1997Abstract Modified 1,2,6-thiadiazine dioxide acyclonucleosides were synthesized using the silylation method. All the compounds were tested as antiviral agents in a wide variety of assay systems. With two compounds, some activity (20, 35 and 14 μg/mL, respectively) was noted against herpes simplex virus, human cytomegalovirus and varicella-zoster virus.
A. I. Esteban, E. De Clercq, A. Martinez
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Tautomerism in Pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-Dioxides
HETEROCYCLES, 1988Etude de la tautomerie des composes du titre en solution par spectroscopies UV, RMN ( 13 C et 15 N) et a l'etat solide par cristallographie par diffraction ...
Carmen Ochoa +4 more
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Reaction of 3,4,4,5-tetrachloro-4H-1,2,6-thiadiazine with benzyltriethylammonium chloride
Tetrahedron Letters, 2018Abstract 3,4,4,5-Tetrachloro-4H-1,2,6-thiadiazine was reacted with BnEt3NCl (10 mol%) to give perchloro-9-thia-1,5,8,10-tetraazaspiro[5.5]undeca-1,4,7,10-tetraene (up to 18% yield), 4,5,6-trichloropyrimidine-2-carbonitrile (up to 44% yield) and four minor side products: 2,7-dichlorothiazolo[5,4-d]pyrimidine-5-carbonitrile, 2-(4-chloro-6H-thiazolo[5,4-
Kalogirou, Andreas S. +5 more
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