Results 81 to 90 of about 202 (136)
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Journal of Heterocyclic Chemistry, 1977
AbstractRefluxing the oxime (1) of 2‐methyl‐2H‐1,2‐benzothiazin‐4(3H)one 1,1‐dioxide with tri‐fluoroacetic acid or with boron trifluoride in acetic acid gives the corresponding N‐acyl derivative (2 or 3) of 4‐amino‐2‐methyl‐2H‐1,2‐benzothiazin‐3(4H)one 1,1‐dioxide.
Harold Zinnes +2 more
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AbstractRefluxing the oxime (1) of 2‐methyl‐2H‐1,2‐benzothiazin‐4(3H)one 1,1‐dioxide with tri‐fluoroacetic acid or with boron trifluoride in acetic acid gives the corresponding N‐acyl derivative (2 or 3) of 4‐amino‐2‐methyl‐2H‐1,2‐benzothiazin‐3(4H)one 1,1‐dioxide.
Harold Zinnes +2 more
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The synthesis of substituted 2H-1,2-benzothiazines 1,1-dioxides
Collection of Czechoslovak Chemical Communications, 1986The base-catalyzed rearrangement of the esters of 2H-1,2-benzothiazolin-3-one-2-acetate 1,1-dioxide (IIa - IIc) afforded substituted 2H-1,2-benzothiazine-3-carboxylate 1,1-dioxides IIIa -IIIc. After N-alkylation and aminolysis the antiinflammatory drugs piroxicam and isoxicam were obtained.
Jiří Svoboda +2 more
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The Journal of Organic Chemistry
In this study, a modular approach toward cyclic sulfoximines and sulfondiimines via palladium-catalyzed intramolecular C-H/C-C activation reactions was reported. Various 1,2-benzothiazines including bicyclic, tricyclic, highly fused ones, ones of the seven-membered ring, along with 1,2-benzothiazine 1-imines were accessed in good yields. KIE experiment
Yifan Ren +7 more
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In this study, a modular approach toward cyclic sulfoximines and sulfondiimines via palladium-catalyzed intramolecular C-H/C-C activation reactions was reported. Various 1,2-benzothiazines including bicyclic, tricyclic, highly fused ones, ones of the seven-membered ring, along with 1,2-benzothiazine 1-imines were accessed in good yields. KIE experiment
Yifan Ren +7 more
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Novel Synthesis of a 2H-1,2-Benzothiazine -1,1-Dioxide Derivative
Synthetic Communications, 2000Abstract We report a novel synthesis of 4-chloro-2-cyclohexyl-6,7-dimethoxy-2H-1,2-benzothiazine-1,1-dioxide 6 from 3,4-dimethoxychalcone 1. Chlorosulfonation of 1 followed by amination, then epoxidation under basic conditions with immediate elimination of the benzoyl group and electrophilic chlorination resulted in 6. A mechanism is suggested.
Jatinder P. Bassin +2 more
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ChemInform Abstract: THE SYNTHESIS OF SOME NEW 1,2‐BENZOTHIAZINES
Chemischer Informationsdienst, 1981AbstractDurch Alkylierung des Benzothiazinderivats (I) mit Alkyliodiden (II) entstehen die Alkylderivate des Esters (III), die mit Aminopyridin (IV) zu den Amiden (V) umgesetzt werden.
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Chemischer Informationsdienst, 1973
AbstractAus den 1,2‐Benzothiazinonen (I) erhält man durch Behandlung mit NaH und den Isocyanaten (II) die Carbamoylderivate (III), die auch aus den Estern (V) mit den Aminen (IV) erhalten werden können.
H. ZINNES +5 more
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AbstractAus den 1,2‐Benzothiazinonen (I) erhält man durch Behandlung mit NaH und den Isocyanaten (II) die Carbamoylderivate (III), die auch aus den Estern (V) mit den Aminen (IV) erhalten werden können.
H. ZINNES +5 more
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A novel photoisomerzation of 1,2‐benzothiazine 1,1‐dioxides to 1,3‐benzothiazine 1,1‐dioxides
Journal of Heterocyclic Chemistry, 2007AbstractA novel facile photoconversion of 4‐hydroxy‐1,2‐bezothiazine 1,1‐dioxides (3a‐e) into 4‐oxo‐1,3‐2H‐benzothiazine 1,1‐dioxides (4a‐e) and 4‐hydroxy‐2‐methyl‐N‐(pyridin‐2‐yl)‐2H‐1,2‐benzothiazine‐3‐carboxamide 1,1‐dioxide (PRX) into N‐methyl saccharin (2) upon 254 nm irradiation in methanol or acetonitrile is reported.
Ibrahim Elghamry +2 more
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Synthesis of 1,2-Benzothiazine via Nickel-Catalyzed Electrochemical Intramolecular Amination
Organic LettersConstructing a C-N bond by merging electrochemistry and nickel catalysis is considered a powerful strategy. Herein, we investigate highly efficient intramolecular amination at room temperature with excellent functional group tolerance. Mechanistic studies suggest that the rapid ligand exchange may lead to the NiI/NiIII catalytic cycle.
Zhao-Ran Liu +4 more
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Archives of Pharmacal Research, 1992
A number of 4-hydroxy-2H (or alkyl)-N-(3-aralkyl-2-thio-1-hydantoinyl)-1,2-benzothiazine-3-carboxamide 1,1-dioxides were synthesized through the reaction of 4-hydroxy-2H (or alkyl)-1,2-benzothiazine-3-carboxylic methyl ester 1,1-dioxide and 1-amino-2-thio-3-aralkyl-4-imidazolones in xylene.
Soon-kyoung Kwon, Myoung-suk Park
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A number of 4-hydroxy-2H (or alkyl)-N-(3-aralkyl-2-thio-1-hydantoinyl)-1,2-benzothiazine-3-carboxamide 1,1-dioxides were synthesized through the reaction of 4-hydroxy-2H (or alkyl)-1,2-benzothiazine-3-carboxylic methyl ester 1,1-dioxide and 1-amino-2-thio-3-aralkyl-4-imidazolones in xylene.
Soon-kyoung Kwon, Myoung-suk Park
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New β-aminovinylketonates with annealated 1,2-benzothiazine-1,1-dioxide fragment
Polyhedron, 2004Abstract New β-aminovinylketones with heterocyclic 1,2-benzothiazine-1,1-dioxide and antipyrine moieties (LH) and their 3d-metal (Co II , Ni II , Cu II , Zn II ) chelates have been synthesized. Two types of chelates can be obtained based on the coordination of the LH ligand, depending when an available carbonyl (CO) group of the antipyrine fragment ...
A.D Garnovskii +10 more
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