The relationship of 1,25-dihydroxyvitamin D and radial bone mass [PDF]
We assessed the association between radial bone mass and vitamin D considering age, estrogen sufficiency and thiazide use in 373 women, aged 20-80 years in a geographically defined area. We measured cortical bone mass of the radius, using photon absorptiometry, and serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, using preliminary chromatography ...
Sowers, MaryFran R. +2 more
openaire +5 more sources
Serum 1,25-dihydroxyvitamin D: an outcome prognosticator in human sepsis. [PDF]
In sepsis, the vitamin D active metabolite 1,25-dihydroxyvitamin D (1,25(OH)2D) may play a crucial role by its action to produce cathelicidin and improve endothelial barrier function, such that a deficiency in 1,25(OH)2D is associated with poor outcome ...
H Bryant Nguyen +5 more
doaj +2 more sources
1,25-Dihydroxyvitamin D3 inhibits the differentiation and migration of T(H)17 cells to protect against experimental autoimmune encephalomyelitis. [PDF]
BackgroundVitamin D(3), the most physiologically relevant form of vitamin D, is an essential organic compound that has been shown to have a crucial effect on the immune responses.
Jae-Hoon Chang +4 more
doaj +2 more sources
Skeletal unloading decreases production of 1,25-dihydroxyvitamin D
The plasma concentration of 1,25-dihydroxyvitamin D [1,25(OH)2D] decreases during skeletal unloading and increases when normal weight bearing is restored. To determine whether these changes in plasma 1,25(OH)2D reflect changes in production, metabolic clearance, or both we measured the kinetics of 1,25(OH)2D metabolism in rats whose skeletons were ...
B P, Halloran +4 more
openaire +3 more sources
Evaluation of a 1,25-Dihydroxyvitamin D Enzyme Immunoassay [PDF]
AbstractBackground: Radioactive reagents are used in most assays for measurement of 1,25-dihydroxyvitamin D [1,25(OH)2D]. We evaluated a 1,25(OH)2D enzyme immunoassay (EIA) from IDS Ltd. that uses solid-phase immunoextraction and colorimetric detection and compared results to those of the thymus radioreceptor assay (RRA) for 1,25(OH)2D.Methods: We ...
Isolde, Seiden-Long, Reinhold, Vieth
openaire +2 more sources
TRPV6 Determines the Effect of Vitamin D3 on Prostate Cancer Cell Growth. [PDF]
Despite remarkable advances in the therapy and prevention of prostate cancer it is still the second cause of death from cancer in industrialized countries.
Gordienko, DV +33 more
core +1 more source
Effect of 1,25-dihydroxyvitamin D3-glycosides on the farrowing process and piglet vitality in a free farrowing system [PDF]
Vitamin D improves the reproductive efficiency in animals. This study aimed to examine the effects of 1,25-dihydroxyvitamin D3-gylcosides (1,25-vitD) on the farrowing process in sows and the vitality of their piglets.
Jahn, Laura
core +3 more sources
1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation [PDF]
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Frahm, Thomas +9 more
core +1 more source
Effects of Single Vitamin D Injection (200,000 Units) on Serum Fibroblast Growth Factor 23 and Sclerostin Levels in Subjects with Vitamin D Deficiency [PDF]
BackgroundVitamin D deficiency remains common in all age groups and affects skeletal and non-skeletal health. Fibroblast growth factor 23 is a bone-derived hormone that regulates phosphate and 1,25-dihydroxyvitamin D homeostasis as a counter regulatory ...
Dongdong Zhang +5 more
doaj +1 more source
The future of vitamin D analogs
The active form of vitamin D3, 1,25-dihydroxyvitamin D3, is a major regulator of bone and calcium homeostasis. In addition, this hormone also inhibits the proliferation and stimulates the differentiation of normal as well as malignant cells ...
Carlien eLeyssens +2 more
doaj +1 more source

