Results 31 to 40 of about 14,595,151 (227)

1,25-dihydroxyvitamin D and PTHrP mediated malignant hypercalcemia in a seminoma [PDF]

open access: yes, 2014
Background: Seminomas have been rarely associated with malignant hypercalcemia. The responsible mechanism of hypercalcemia in this setting has been described to be secondary to 1,25-dihydroxyvitamin D secretion. The relationship with PTHrP has not been
Carlos Rodrigo Camara-Lemarroy   +13 more
core   +2 more sources

Advances in the study of the correlation between vitamin D-24-hydroxylase and thyroid carcinoma [PDF]

open access: yesJichu yixue yu linchuang, 2023
Thyroid carcinoma(TC) is the most common malignant tumor of endocrine system. Patients with vitamin D deficiency have an increased risk of TC. Vitamin D-24-hydroxylase (CYP24A1) is main inactivating enzyme of active vitamin D which may inhibit the ...
CHEN Shijing, FU Jinglan, DENG Yuanyuan, ZHANG Ying, LIU Huixia
doaj   +1 more source

Analysis by high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells [PDF]

open access: yes, 1990
HL-60 leukemic cells were differentiated along the neutrophilic pathway with retinoic acid (RA) or along the monocytic pathway with 1,25-dihydroxyvitamin D3 (1,25(OH)2D3).
Seifert, Roland, Jungblut, P. R.
core   +1 more source

Clinical Significance of FGF-23 in Patients with CKD

open access: yesInternational Journal of Nephrology, 2011
FGF23 is a bone-derived hormone that plays an important role in the regulation of phosphate and 1,25-dihydroxy vitamin D metabolism. FGF23 principally acts in the kidney to induce urinary phosphate excretion and suppress 1,25-dihydroxyvitamin D synthesis
Domenico Russo, Yuri Battaglia
doaj   +1 more source

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes. [PDF]

open access: yes, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G.   +7 more
core   +1 more source

Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

open access: yeseLife, 2022
Pregnancy 25-hydroxyvitamin D [25(OH)D] concentrations are associated with maternal and fetal health outcomes. Using physiological human placental perfusion and villous explants, we investigate the role of the placenta in regulating the relationships ...
Brogan Ashley   +26 more
doaj   +1 more source

Is 1,25-Dihydroxyvitamin D Required for Reproduction?

open access: yesExperimental Biology and Medicine, 1989
The role of 1,25-dihydroxyvitamin D (1,25-(OH)2D) in avian and mammalian reproduction is examined. 1,25-Dihydroxyvitamin D is required, in both the avian and mammalian species, for maintenance of normocalcemia, adequate intestinal calcium absorption, bone turnover, and mineral homeostasis throughout the reproductive cycle--just as it is required in the
openaire   +2 more sources

Pregnancy‐ and lactation‐associated osteoporosis: A position statement of the IAPM, IOF, ECTS, ESCEO, IMS, and EMAS

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji   +20 more
wiley   +1 more source

1,25-dihydroxyvitamin D3 and development of tuberculosis in cattle [PDF]

open access: yes, 2003
This report describes the presence and activity of 1,25-dihydroxyvitamin D3 (1,25-D3) in experimental bovine tuberculosis. Animals that went on to develop tuberculous lesions exhibited a rapid transient increase in serum 1,25-D3 within the first 2 weeks ...
Hewinson, R. G.   +4 more
core  

A Case Report of Compound Heterozygous CYP24A1 Mutations Leading to Nephrolithiasis Successfully Treated with Ketoconazole

open access: yesCase Reports in Nephrology and Dialysis, 2017
CYP24A1 is an enzyme that inactivates vitamin D. Loss-of-function mutations in this enzyme are rare but have been linked with idiopathic infantile hypercalcemia as well as adult-onset nephrocalcinosis and nephrolithiasis.
Emma Davidson Peiris, Raghav Wusirika
doaj   +1 more source

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