Results 51 to 60 of about 14,595,151 (227)

Novel mechanisms in the regulation of 5-lipoxygenase gene expression by 1,25-dihydroxyvitamin D3 and transforming growth factor ß [PDF]

, 2004
Die 5 Lipoxygenase (5 LO) ist das Schlüsselenzym in der Synthese von Leukotrienen. Sie wird auf transkriptioneller und posttranskriptioneller Ebene reguliert.
Seuter, Sabine
core  

Biological activity of 24,24-difluoro-1,25-dihydroxyvitamin D3

, 1983
The biological activity of 24,24-difluoro-1,25-dihydroxyvitamin D3 was compared with 1,25-dihydroxyvitamin D3 in the rat. The 24,24-difluoro-1,25-dihydroxyvitamin D3 has a potency of approximately 5-10 times that of 1,25-dihydroxyvitamin D3 in the known ...
S. Okamoto, N. Ikekawa, Y. Tanaka, Y. Kobayashi, H. F. DeLuca   +4 more
core   +1 more source

Restoring Mouth Opening in Systemic Sclerosis: A Scoping Review of Interventions

Oral Diseases, EarlyView.
ABSTRACT Objectives To map and characterize the therapeutic strategies described in the literature for the management of microstomia in patients with systemic sclerosis. Methods This scoping review was conducted in accordance with the PRISMA‐ScR guidelines. Searches were performed in Medline/PubMed, Embase, Scopus, Web of Science, Cochrane Library, and
Beatriz Borba Barros Bernardo, Lucas Nascimento Ribeiro, Luiz Alcino Monteiro Gueiros, Belmiro Cavalcanti do Egito Vasconcelos, Sandra Lúcia Dantas Moraes, Marianne Vasconcelos Carvalho   +5 more
wiley   +1 more source

Hematological parameters by cutoffs of 1,25-Dihydroxyvitamin D.

, 2015
Hb = Hemoglobin; MCH = mean corpuscular/cellular hemoglobin; MCV = mean corpuscular/cell volumeHematological parameters by cutoffs of 1,25-Dihydroxyvitamin D.
Jana B. Ernst (725980), Joachim Kuhn (635688), Armin Zittermann (725983), Tobias Becker (725981), Jan F. Gummert (725982)   +4 more
core   +1 more source

Relationship between vitamin D deficiency and early implant failure and osseointegration

Periodontology 2000, EarlyView.
Abstract Background This systematic review investigated the relationship between pre‐operative vitamin D levels and implant osseointegration and implant‐related outcomes. It also assessed studies involving vitamin D supplementation before implant placement.
Richard J. Miron, Nathan E. Estrin, Ana Paz, Reinhard Gruber, Nima Farshidfar, Yufeng Zhang, Anton Sculean, Thomas G. Wiedemann, Paras Ahmad   +8 more
wiley   +1 more source

Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation

Frontiers in Pharmacology, 2020
Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on immunomodulatory drugs that reduce disease recurrence and severity.
Larissa Ragozo Cardoso de Oliveira, Luiza Ayumi Nishiyama Mimura, Thais Fernanda de Campos Fraga-Silva, Larissa Lumi Watanabe Ishikawa, Ana Angélica Henrique Fernandes, Sofia Fernanda Gonçalves Zorzella-Pezavento, Alexandrina Sartori   +6 more
doaj   +1 more source

Historical aspects of vitamin D

Endocrine Connections, 2022
Vitamin D has many physiological functions including upregulation of intestinal calcium and phosphate absorption, mobilization of bone resorption, renal reabsorption of calcium as well as actions on a variety of pleiotropic functions. It is believed that
Glenville Jones
doaj   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

1,25-Dihydroxyvitamin D3 target cells in immature pancreatic islets

, 1987
Target cells of 1,25-dihydroxyvitamin D3 were identified by autoradiography in islets from rats of different ages. Nuclei of pancreatic islet cells selectively concentrated 1,25-[3H]dihydroxyvitamin D3 but not 25-[3H]hydroxyvitamin D3 or 24,25-[3H ...
M. Sar, H. F. DeLuca, S. A. Clark, W. E. Stumpf   +3 more
core   +1 more source

Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: A nested case-control study [PDF]

, 2014
Vitamin D pathway single nucleotide polymorphisms (SNPs) are potentially useful proxies for investigating whether circulating vitamin D metabolites [total 25-hydroxyvitamin-D, 25(OH)D; 1,25-dihydroxyvitamin, 1,25(OH)2D] are causally related to prostate ...
Hamdy, FC, Bonilla, Carolina, Bonilla, C, Kemp, John P., Donovan, JL, Chris Metcalfe, Martin, Richard M., Mark Lathrop, Neal, DE, Smith, GD, Lathrop, M, Metcalfe, Chris, Lewis, S, Fraser, WD, Carolina Bonilla, Lewis, Sarah, J. Athene Lane, Neal, David E., David E. Neal, Freddie C. Hamdy, Lane, J. Athene, John P. Kemp, Evans, David M., David M. Evans, Lane, JA, William D. Fraser, Kemp, JP, Gilbert, Rebecca, Rebecca Gilbert, Hamdy, Freddie C., Evans, DM, Martin, RM, Gilbert, R, Smith, George Davey, Richard M. Martin, Jenny L. Donovan, Donovan, Jenny L., Metcalfe, C, Lathrop, Mark, Sarah Lewis, Fraser, William D., George Davey Smith   +41 more
core   +1 more source