Results 31 to 40 of about 300,590 (210)

1,25-Dihydroxyvitamin D3 Enhances Bovine Mammary Epithelial Innate Immune Responses [PDF]

, 2010
Bovine mammary epithelial cells that were treated with bacterial lipopolysaccharide and 1,25-dihydroxyvitamin D3 showed an increase in the expression of the genes for inducible nitric oxide synthase (iNOS) and S100 calcium binding protein A12 (S100 ...
Nelson, Corwin, Beitz, Donald, Lippolis, John, Reinhardt, Timothy   +3 more
core   +1 more source

Unilateral nephrectomy and 1,25-dihydroxyvitamin D3

Kidney International, 1983
Several renal functions respond to nephron loss by a compensatory adaptation. Whether the production of 1,25(OH)2D3 also adapts to a renal mass reduction is still a matter of controversy. In the present study we have investigated in rats the influence of unilateral nephrectomy, in both the acute (48 hr) and chronic (2 to 6 weeks) state, on plasma 1,25 ...
Taylor, Carol M., Caverzasio, Joseph, Jung, André, Trechsel, Ulrich, Fleisch, Herbert, Bonjour, Jean-Philippe.   +5 more
openaire   +2 more sources

1,25-Dihydroxyvitamin D3 and the Immune System

Experimental Biology and Medicine, 1989
There is substantial evidence that lymphocytes and monocytes are targets for the actions of the hormonal form of vitamin D, 1,25-(OH)2D3 and that 1,25-(OH)2D3 acts to modulate the proliferation, differentiation, and immune functions of these cells. The effects of the hormone on lymphocytes are mediated directly as well as indirectly via the accessory ...
S C, Manolagas, F G, Hustmyer, X P, Yu
openaire   +2 more sources

Calcitriol Prevents Neuroinflammation and Reduces Blood-Brain Barrier Disruption and Local Macrophage/Microglia Activation

Frontiers in Pharmacology, 2020
Multiple sclerosis (MS) is a progressive disease of the central nervous system (CNS) that involves damage to the myelin sheath surrounding axons. MS therapy is based on immunomodulatory drugs that reduce disease recurrence and severity.
Larissa Ragozo Cardoso de Oliveira, Luiza Ayumi Nishiyama Mimura, Thais Fernanda de Campos Fraga-Silva, Larissa Lumi Watanabe Ishikawa, Ana Angélica Henrique Fernandes, Sofia Fernanda Gonçalves Zorzella-Pezavento, Alexandrina Sartori   +6 more
doaj   +1 more source

Exogenous Vitamin D3 Modulates Response of Bovine Macrophages to Mycobacterium avium subsp. paratuberculosis Infection and Is Dependent Upon Stage of Johne’s Disease

Frontiers in Cellular and Infection Microbiology, 2022
Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of ruminant enteritis, targets intestinal macrophages. During infection, macrophages contribute to mucosal inflammation and development of granulomas in the small intestine which ...
Taylor L. T. Wherry, Taylor L. T. Wherry, Rohana P. Dassanayake, Eduardo Casas, Shankumar Mooyottu, John P. Bannantine, Judith R. Stabel   +6 more
doaj   +1 more source

Advances in the study of the correlation between vitamin D-24-hydroxylase and thyroid carcinoma [PDF]

Jichu yixue yu linchuang, 2023
Thyroid carcinoma(TC) is the most common malignant tumor of endocrine system. Patients with vitamin D deficiency have an increased risk of TC. Vitamin D-24-hydroxylase (CYP24A1) is main inactivating enzyme of active vitamin D which may inhibit the ...
CHEN Shijing, FU Jinglan, DENG Yuanyuan, ZHANG Ying, LIU Huixia
doaj   +1 more source

Phosphorylation of the 1,25-dihydroxyvitamin D3 receptor. A primary event in 1,25-dihydroxyvitamin D3 action.

Journal of Biological Chemistry, 1990
1,25-Dihydroxyvitamin D3 is believed to mediate the regulation of calcium metabolism by a steroid hormone receptor mechanism. We now demonstrate that phosphorylation of the 1,25-dihydroxyvitamin D3 receptor occurs rapidly in embryonic chick duodenal organ culture in response to 1,25-dihydroxyvitamin D3.
T A, Brown, H F, DeLuca
openaire   +2 more sources

1,25-Dihydroxyvitamin D3 protects obese rats from metabolic syndrome via promoting regulatory T cell-mediated resolution of inflammation

Acta Pharmaceutica Sinica B, 2018
Vitamin D3 has been found to produce therapeutic effects on obesity-associated insulin resistance and dyslipidemia through its potent anti-inflammatory activity, but the precise immunomodulatory mechanism remains poorly understood.
Wen Jin, Bing Cui, Pingping Li, Fang Hua, Xiaoxi Lv, Jichao Zhou, Zhuowei Hu, Xiaowei Zhang   +7 more
doaj   +1 more source

Toll-Like Receptor Signaling in Bovine Macrophages Increases 1,25-Dihydroxyvitamin D3 Production [PDF]

, 2008
Recognition of pathogen associated molecular patterns by Toll-like receptors (TLR) increases 1α-hydroxylase expression in bovine macrophages. This results in increased conversion of 25-hydroxyvitamin D3 (25(OH)D3) to 1,25- dihydroxyvitamin D3 (1,25(OH)
Nelson, Corwin, Beitz, Donald, Lippolis, John, Reinhardt, Tim   +3 more
core   +1 more source

1,25(OH)2 vitamin D3, and retinoic acid antagonize endothelin-stimulated hypertrophy of neonatal rat cardiac myocytes. [PDF]

, 1996
1,25 (OH)(2) Vitamin D-3 (VD3) and retinoic acid (RA) function as ligands for nuclear receptors which regulate transcription, Though the cardiovascular system is not thought to represent a classical target for these ligands, it is clear that both cardiac
Gardner, D. G., J Wu, Garami, Miklós, Cheng, T., T Cheng, Wu, J., M Garami, D G Gardner   +7 more
core   +1 more source